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NFE2L2 elisa kit :: Human Nuclear factor erythroid 2-related factor 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS289787
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $430 +1 FREE 8GB USB
96-Strip-Wells  /  $570 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,515 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,520 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Nuclear factor erythroid 2-related factor 2 (NFE2L2), ELISA Kit

★Popular Item★
 Also Known As   

Human Nuclear factor erythroid 2-related factor 2 ELISA Kit

 Product Synonym Names    Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2; NFE2L2; NRF2
 Product Gene Name   

NFE2L2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS289787 Testing Data    Testing Data PDF
 OMIM    600492
 3D Structure    ModBase 3D Structure for Q16236
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 Species Reactivity    Human
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 Assay Type    Sandwich
 Detection Range    0.312-20 ng/mL
 Sensitivity    0.184 ng/mL
 Intra-Assay CV    <=8.1%
 Inter-Assay CV    <=10.2%
 Recovery    99%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of NFE2L2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for NFE2L2 purchase    MBS289787 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Nuclear factor erythroid 2-related factor 2 (NFE2L2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.312-20 ng/mL in biological research samples containing NFE2L2, with an estimated sensitivity of 0.184 ng/mL. The ELISA analytical biochemical technique of the MBS289787 kit is based on NFE2L2 antibody-NFE2L2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NFE2L2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NFE2L2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for NFE2L2 elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Standard Curve/Testing Data of NFE2L2 elisa kit    NFE2L2 elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS289787. Click to request current manual
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NCBI/Uniprot data below describe general gene information for NFE2L2. It may not necessarily be applicable to this product.
 NCBI GI #    224028257
 NCBI GeneID    4780
 NCBI Accession #    NP_001138884.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001145412.3 [Other Products]
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 UniProt Primary Accession #    Q16236 [Other Products]
 UniProt Secondary Accession #    Q53RW6; Q59HH2; Q96F71; B2RBU2; B4E338; E9PGJ7 [Other Products]
 UniProt Related Accession #    Q16236 [Other Products]
 Molecular Weight    65,356 Da
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 NCBI Official Full Name    nuclear factor erythroid 2-related factor 2 isoform 2
 NCBI Official Synonym Full Names    nuclear factor, erythroid 2 like 2
 NCBI Official Symbol    NFE2L2 [Similar Products]
 NCBI Official Synonym Symbols   
NRF2; HEBP1
[Similar Products]
 NCBI Protein Information    nuclear factor erythroid 2-related factor 2
 UniProt Protein Name    Nuclear factor erythroid 2-related factor 2
 UniProt Synonym Protein Names   
HEBP1; Nuclear factor, erythroid derived 2, like 2
 Protein Family    Nuclear factor erythroid 2-related factor
 UniProt Gene Name    NFE2L2 [Similar Products]
 UniProt Synonym Gene Names    NRF2; NF-E2-related factor 2; NFE2-related factor 2 [Similar Products]
 UniProt Entry Name    NF2L2_HUMAN
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 NCBI Summary for NFE2L2    This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for this gene. [provided by RefSeq, Sep 2015]
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 UniProt Comments for NFE2L2    NRF2: a transcription factor that regulates basal expression and antioxidant induction of a transcription factor for NAD(P)H:quinone oxidoreductase-1 (NQO1) and other detoxifying genes. Targeted for proteasomal degradation by INrf2. Oxidative stress causes its phosphorylation and release from INrf2.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 2q31

Cellular Component: centrosome; chromatin; cytoplasm; cytosol; nucleus; plasma membrane

Molecular Function: DNA binding; protein binding; protein domain specific binding; transcription factor activity

Biological Process: cell redox homeostasis; cellular response to glucose starvation; inflammatory response; positive regulation of blood coagulation; positive regulation of glucose import; positive regulation of transcription from RNA polymerase II promoter; proteasomal ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-independent protein catabolic process; protein ubiquitination; regulation of embryonic development; transcription from RNA polymerase II promoter; unfolded protein response
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 Research Articles on NFE2L2    1. Myrosinase treated glucoerucin induces the nuclear translocation of Nrf2 in HT-29 cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with NFE2L2 elisa kitPathways associated with NFE2L2 elisa kit
 Reference Product  PubMed Publications
 HMOX1 elisa kit  >1277 publications with NFE2L2 and HMOX1
 KEAP1 elisa kit  >893 publications with NFE2L2 and KEAP1
 JUN elisa kit  >498 publications with NFE2L2 and JUN
 CUL3 elisa kit  >73 publications with NFE2L2 and CUL3
 MAFK elisa kit  >32 publications with NFE2L2 and MAFK
 MAFG elisa kit  >25 publications with NFE2L2 and MAFG
 GSTA2 elisa kit  >24 publications with NFE2L2 and GSTA2
 MAFF elisa kit  >4 publications with NFE2L2 and MAFF
 UBC elisa kit  >4 publications with NFE2L2 and UBC
 EIF2AK3 elisa kit  >1 publications with NFE2L2 and EIF2AK3
 Products by Pathway  Pathway Diagram
 AhR Pathway antibodies  AhR Pathway Diagram
 Keap1-Nrf2 Pathway antibodies  Keap1-Nrf2 Pathway Diagram
 Oxidative Stress Pathway antibodies  Oxidative Stress Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram
Diseases associated with NFE2L2 elisa kitOrgans/Tissues associated with NFE2L2 elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >752 publications with NFE2L2 and Inflammation
 Nervous System Diseases Antibodies  >420 publications with NFE2L2 and Nervous System Diseases
 Necrosis Antibodies  >349 publications with NFE2L2 and Necrosis
 Liver Diseases Antibodies  >334 publications with NFE2L2 and Liver Diseases
 Drug-Induced Liver Injury Antibodies  >149 publications with NFE2L2 and Drug-Induced Liver Injury
 Kidney Diseases Antibodies  >148 publications with NFE2L2 and Kidney Diseases
 Fibrosis Antibodies  >135 publications with NFE2L2 and Fibrosis
 Liver Neoplasms Antibodies  >123 publications with NFE2L2 and Liver Neoplasms
 Gastrointestinal Diseases Antibodies  >121 publications with NFE2L2 and Gastrointestinal Diseases
 Heart Diseases Antibodies  >119 publications with NFE2L2 and Heart Diseases
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >726 publications with NFE2L2 and Liver
 Blood Antibodies  >589 publications with NFE2L2 and Blood
 Lung Antibodies  >490 publications with NFE2L2 and Lung
 Brain Antibodies  >437 publications with NFE2L2 and Brain
 Vascular Antibodies  >316 publications with NFE2L2 and Vascular
 Kidney Antibodies  >260 publications with NFE2L2 and Kidney
 Muscle Antibodies  >257 publications with NFE2L2 and Muscle
 Heart Antibodies  >241 publications with NFE2L2 and Heart
 Skin Antibodies  >146 publications with NFE2L2 and Skin
 Intestine Antibodies  >105 publications with NFE2L2 and Intestine
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