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P-Cadherin elisa kit :: Human P-Cadherin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2500111
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

P-Cadherin, ELISA Kit

★Popular Item★
 Also Known As   

Human P-Cadherin (Cadherin, Placental) ELISA Kit

 Product Gene Name   

P-Cadherin elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    114021
 3D Structure    ModBase 3D Structure for P22223
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human P-Cadherin. No significant cross-reactivity or interference between Human P-Cadherin and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human P-Cadherin and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    62.5--4000pg/mL
 Sensitivity    37.5pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of P-Cadherin elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for P-Cadherin purchase    MBS2500111 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the P-Cadherin, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5--4000pg/mL in biological research samples containing P-Cadherin, with an estimated sensitivity of 37.5pg/mL. The ELISA analytical biochemical technique of the MBS2500111 kit is based on P-Cadherin antibody-P-Cadherin antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect P-Cadherin antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, P-Cadherin. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for P-Cadherin elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of P-Cadherin in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human P-Cadherin. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human P-Cadherin and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human P-Cadherin, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human P-Cadherin. You can calculate the concentration of Human P-Cadherin in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of P-Cadherin elisa kit    P-Cadherin elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2500111. Click to request current manual
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NCBI/Uniprot data below describe general gene information for P-Cadherin. It may not necessarily be applicable to this product.
 NCBI GI #    2950172
 NCBI GeneID    1001
 NCBI Accession #    CAA65093.1 [Other Products]
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 UniProt Primary Accession #    P22223 [Other Products]
 UniProt Secondary Accession #    Q05DI6; B2R6F4 [Other Products]
 UniProt Related Accession #    P22223 [Other Products]
 Molecular Weight    86,552 Da
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 NCBI Official Full Name    P-cadherin, partial
 NCBI Official Synonym Full Names    cadherin 3, type 1, P-cadherin (placental)
 NCBI Official Symbol    CDH3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    cadherin-3; calcium-dependent adhesion protein, placental
 UniProt Protein Name    Cadherin-3
 UniProt Synonym Protein Names   
Placental cadherin; P-cadherin
 UniProt Gene Name    CDH3 [Similar Products]
 UniProt Synonym Gene Names    CDHP; P-cadherin [Similar Products]
 UniProt Entry Name    CADH3_HUMAN
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 NCBI Summary for P-Cadherin    This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008]
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 UniProt Comments for P-Cadherin    CDH3: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Interacts with CDCP1. Expressed in some normal epithelial tissues and in some carcinoma cell lines. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Cell adhesion

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: cell-cell adherens junction; cytoplasm; integral to membrane; plasma membrane

Molecular Function: calcium ion binding

Biological Process: response to drug; positive regulation of insulin-like growth factor receptor signaling pathway; intercellular junction assembly and maintenance; wound healing; positive regulation of melanin biosynthetic process; Wnt receptor signaling pathway through beta-catenin; negative regulation of transforming growth factor-beta2 production; hair cycle process; retinal homeostasis; cell-cell adhesion; negative regulation of catagen; positive regulation of monophenol monooxygenase activity; visual perception; keratinization; cell adhesion; homophilic cell adhesion

Disease: Ectodermal Dysplasia, Ectrodactyly, And Macular Dystrophy Syndrome; Hypotrichosis, Congenital, With Juvenile Macular Dystrophy
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 Research Articles on P-Cadherin    1. Positive N-cadherin and P-cadherin expression closely correlated with clinicopathological and biological behaviors, and poor-prognosis of gallbladder cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with P-Cadherin elisa kitPathways associated with P-Cadherin elisa kit
 Reference Product  PubMed Publications
 CDH1 elisa kit  >21 publications with P-Cadherin and CDH1
 CTNNB1 elisa kit  >4 publications with P-Cadherin and CTNNB1
 Products by Pathway  Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Junction Organization Pathway antibodies  Cell Junction Organization Pathway Diagram
 Cell-Cell Communication Pathway antibodies  Cell-Cell Communication Pathway Diagram
 Cell-cell Junction Organization Pathway antibodies  Cell-cell Junction Organization Pathway Diagram
Diseases associated with P-Cadherin elisa kitOrgans/Tissues associated with P-Cadherin elisa kit
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >28 publications with P-Cadherin and Skin Diseases
 Breast Neoplasms Antibodies  >13 publications with P-Cadherin and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >4 publications with P-Cadherin and Neoplasms, Experimental
 Adenoma Antibodies  >4 publications with P-Cadherin and Adenoma
 Lung Neoplasms Antibodies  >4 publications with P-Cadherin and Lung Neoplasms
 Lung Diseases Antibodies  >4 publications with P-Cadherin and Lung Diseases
 Neoplasm Metastasis Antibodies  >4 publications with P-Cadherin and Neoplasm Metastasis
 Ectodermal dysplasia, ectrodactyly, and macular dystrophy Antibodies  >4 publications with P-Cadherin and Ectodermal dysplasia, ectrodactyly, and macular dystrophy
 Inflammation Antibodies  >3 publications with P-Cadherin and Inflammation
 Kidney Diseases Antibodies  >2 publications with P-Cadherin and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >7 publications with P-Cadherin and Skin
 Intestine Antibodies  >5 publications with P-Cadherin and Intestine
 Lung Antibodies  >5 publications with P-Cadherin and Lung
 Liver Antibodies  >5 publications with P-Cadherin and Liver
 Stomach Antibodies  >4 publications with P-Cadherin and Stomach
 Eye Antibodies  >4 publications with P-Cadherin and Eye
 Blood Antibodies  >4 publications with P-Cadherin and Blood
 Embryonic Tissue Antibodies  >4 publications with P-Cadherin and Embryonic Tissue
 Thyroid Antibodies  >3 publications with P-Cadherin and Thyroid
 Kidney Antibodies  >2 publications with P-Cadherin and Kidney
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