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PAN3 elisa kit :: Human PAN3 poly (A) specific ribonuclease subunit homolog (S. cerevisiae) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9320141 PAN3 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PAN3 poly (A) specific ribonuclease subunit homolog (S. cerevisiae), ELISA Kit

 Also Known As   

Human PAB-dependent poly, PAN3 ELISA Kit

 Product Synonym Names    Human PAB-dependent poly (PAN3) ELISA kit; RP11-179F17.3; OTTHUMP00000018179; PAB-dependent poly (A) -specific ribonuclease subunit 3; PABP-dependent poly (A) nuclease 3; PABP1-dependent poly A-specific ribonuclease subunit PAN3; PAN3 poly (A) specific ribonuclease subunit homolog (S. cerevisiae)
 Product Gene Name   

PAN3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q58A45
 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PAN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PAN3 purchase    MBS9320141 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PAN3 poly (A) specific ribonuclease subunit homolog (S. cerevisiae) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PAN3. The ELISA analytical biochemical technique of the MBS9320141 kit is based on PAN3 antibody-PAN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PAN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PAN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PAN3. It may not necessarily be applicable to this product.
 NCBI GI #    281427224
 NCBI GeneID    255967
 NCBI Accession #    NP_787050.6 [Other Products]
 NCBI GenBank Nucleotide #    NM_175854.7 [Other Products]
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 UniProt Primary Accession #    Q58A45 [Other Products]
 UniProt Secondary Accession #    Q0D2P2; Q5HYG6; Q5T515; Q5T516; Q5TBA0; Q76E13; A0N0X1; A1A4Y8; A1A4Y9; B1ALF1; B7Z3W7 [Other Products]
 UniProt Related Accession #    Q58A45 [Other Products]
 Molecular Weight    95,613 Da
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 NCBI Official Full Name    PAB-dependent poly(A)-specific ribonuclease subunit PAN3
 NCBI Official Synonym Full Names    PAN3 poly(A) specific ribonuclease subunit
 NCBI Official Symbol    PAN3 [Similar Products]
 NCBI Protein Information    PAB-dependent poly(A)-specific ribonuclease subunit PAN3; PAB-dependent poly(A)-specific ribonuclease subunit PAN3; PAB1P-dependent poly(A)-nuclease; PABP-dependent poly(A) nuclease 3; PAN deadenylation complex subunit 3; PAN3 poly(A) specific ribonuclease subunit homolog; PAB-dependent poly(A)-specific ribonuclease subunit 3; PABP1-dependent poly A-specific ribonuclease subunit PAN3
 UniProt Protein Name    PAB-dependent poly(A)-specific ribonuclease subunit PAN3
 UniProt Synonym Protein Names   
PAB1P-dependent poly(A)-nuclease; PAN deadenylation complex subunit 3; hPan3
 UniProt Gene Name    PAN3 [Similar Products]
 UniProt Synonym Gene Names    hPan3 [Similar Products]
 UniProt Entry Name    PAN3_HUMAN
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 UniProt Comments for PAN3    PAN3: Functions in cytoplasmic mRNA decay. As part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity. Belongs to the protein kinase superfamily. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 13q12.2

Cellular Component: cytosol

Molecular Function: protein binding; poly(A)-specific ribonuclease activity; metal ion binding; transferase activity, transferring phosphorus-containing groups; ATP binding

Biological Process: deadenylation-dependent decapping; poly(A) tail shortening; gene expression; protein targeting; mRNA catabolic process, deadenylation-dependent decay
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 Research Articles on PAN3    1. hPan2 and hPan3 have roles in mRNA decay and exhibit cytoplasmic co-localization
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PAN3 elisa kitDiseases associated with PAN3 elisa kit
 Products by Pathway  Pathway Diagram
 Deadenylation Of MRNA Pathway antibodies  Deadenylation Of MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 Disease Name  Pubmed Publications
 Leukemia, Lymphoid Antibodies  >1 publications with PAN3 and Leukemia, Lymphoid
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