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PDCD1 elisa kit :: Human PDCD1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2502682
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PDCD1, ELISA Kit

★Popular Item★
 Also Known As   

Human PDCD1 (Programmed Cell Death Protein 1) ELISA Kit

 Product Gene Name   

PDCD1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    109100
 3D Structure    ModBase 3D Structure for Q15116
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human PDCD1. No significant cross-reactivity or interference between Human PDCD1 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human PDCD1 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PDCD1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PDCD1 purchase    MBS2502682 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PDCD1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing PDCD1, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2502682 kit is based on PDCD1 antibody-PDCD1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDCD1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDCD1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PDCD1 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of PDCD1 in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human PDCD1. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human PDCD1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human PDCD1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human PDCD1. You can calculate the concentration of Human PDCD1 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of PDCD1 elisa kit    PDCD1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2502682. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PDCD1. It may not necessarily be applicable to this product.
 NCBI GI #    167857792
 NCBI GeneID    5133
 NCBI Accession #    NP_005009.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_005018.2 [Other Products]
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 UniProt Primary Accession #    Q15116 [Other Products]
 UniProt Secondary Accession #    O00517; Q8IX89 [Other Products]
 UniProt Related Accession #    Q15116 [Other Products]
 Molecular Weight    31,647 Da
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 NCBI Official Full Name    programmed cell death protein 1
 NCBI Official Synonym Full Names    programmed cell death 1
 NCBI Official Symbol    PDCD1 [Similar Products]
 NCBI Official Synonym Symbols   
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
[Similar Products]
 NCBI Protein Information    programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2
 UniProt Protein Name    Programmed cell death protein 1
 UniProt Synonym Protein Names   
CD_antigen: CD279
 Protein Family    Programmed cell death protein
 UniProt Gene Name    PDCD1 [Similar Products]
 UniProt Synonym Gene Names    PD1; Protein PD-1; hPD-1 [Similar Products]
 UniProt Entry Name    PDCD1_HUMAN
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 NCBI Summary for PDCD1    This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PDCD1    PDCD1: a single-pass type I membrane protein. A negative regulator of activated T cells, is upregulated in human and mouse 'exhausted' T cells during persistent viral infection. A marker of angioimmunoblastic T-cell lymphoma and germinal center associated T cells.

Protein type: Apoptosis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q37.3

Cellular Component: integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; signal transducer activity

Biological Process: apoptosis; multicellular organismal development; T cell costimulation; signal transduction; humoral immune response

Disease: Systemic Lupus Erythematosus
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 Research Articles on PDCD1    1. among the follicular helper T cells markers, PD-1 was most frequently expressed in cutaneous T-cell lymphomas
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PDCD1 elisa kitPathways associated with PDCD1 elisa kit
 Reference Product  PubMed Publications
 CD4 elisa kit  >415 publications with PDCD1 and CD4
 CD274 elisa kit  >334 publications with PDCD1 and CD274
 PDCD1LG2 elisa kit  >99 publications with PDCD1 and PDCD1LG2
 PTPN6 elisa kit  >7 publications with PDCD1 and PTPN6
 PTPN11 elisa kit  >7 publications with PDCD1 and PTPN11
 HLA-DR4 elisa kit  >1 publications with PDCD1 and HLA-DR4
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 PD-1 Signaling Pathway antibodies  PD-1 Signaling Pathway Diagram
 T Cell Receptor Signaling Pathway antibodies  T Cell Receptor Signaling Pathway Diagram
 T Cell Receptor Signaling Pathway antibodies  T Cell Receptor Signaling Pathway Diagram
Diseases associated with PDCD1 elisa kitOrgans/Tissues associated with PDCD1 elisa kit
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >146 publications with PDCD1 and Liver Diseases
 Inflammation Antibodies  >115 publications with PDCD1 and Inflammation
 Melanoma Antibodies  >79 publications with PDCD1 and Melanoma
 Necrosis Antibodies  >74 publications with PDCD1 and Necrosis
 Lupus Erythematosus, Systemic Antibodies  >72 publications with PDCD1 and Lupus Erythematosus, Systemic
 Lung Diseases Antibodies  >58 publications with PDCD1 and Lung Diseases
 Lung Neoplasms Antibodies  >38 publications with PDCD1 and Lung Neoplasms
 Adenocarcinoma Antibodies  >35 publications with PDCD1 and Adenocarcinoma
 Kidney Diseases Antibodies  >28 publications with PDCD1 and Kidney Diseases
 Liver Neoplasms Antibodies  >26 publications with PDCD1 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >937 publications with PDCD1 and Blood
 Kidney Antibodies  >36 publications with PDCD1 and Kidney
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