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PECAM1/CD31 elisa kit :: Human PECAM1/CD31 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2514587
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PECAM1/CD31, ELISA Kit

★Popular Item★
 Also Known As   

Human PECAM1/CD31 (Platelet/Endothelial Cell Adhesion Molecule 1) ELISA Kit

 Product Gene Name   

PECAM1/CD31 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    173445
 3D Structure    ModBase 3D Structure for P16284
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human PECAM1/CD31. No significant cross-reactivity or interference between Human PECAM1/CD31 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human PECAM1/CD31 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    31.25--2000pg/mL
 Sensitivity    18.75pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PECAM1/CD31 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PECAM1/CD31 purchase    MBS2514587 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PECAM1/CD31, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.25--2000pg/mL in biological research samples containing PECAM1/CD31, with an estimated sensitivity of 18.75pg/mL. The ELISA analytical biochemical technique of the MBS2514587 kit is based on PECAM1/CD31 antibody-PECAM1/CD31 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PECAM1/CD31 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PECAM1/CD31. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PECAM1/CD31 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of PECAM1/CD31 in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human PECAM1/CD31. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human PECAM1/CD31 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human PECAM1/CD31, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human PECAM1/CD31. You can calculate the concentration of Human PECAM1/CD31 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of PECAM1/CD31 elisa kit    PECAM1/CD31 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2514587. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PECAM1/CD31. It may not necessarily be applicable to this product.
 NCBI GI #    313760624
 NCBI GeneID    5175
 NCBI Accession #    NP_000433.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_000442.4 [Other Products]
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 UniProt Primary Accession #    P16284 [Other Products]
 UniProt Secondary Accession #    Q6LDA9; Q8TBH1; Q96RF5; Q96RF6; Q9NP65; Q9NPB7; Q9NPG9; Q9NQS9; Q9NQT0; A8K3S7; D3DU31 [Other Products]
 UniProt Related Accession #    P16284 [Other Products]
 Molecular Weight    81,378 Da
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 NCBI Official Full Name    platelet endothelial cell adhesion molecule
 NCBI Official Synonym Full Names    platelet/endothelial cell adhesion molecule 1
 NCBI Official Symbol    PECAM1 [Similar Products]
 NCBI Official Synonym Symbols   
CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
[Similar Products]
 NCBI Protein Information    platelet endothelial cell adhesion molecule; CD31 antigen
 UniProt Protein Name    Platelet endothelial cell adhesion molecule
 UniProt Synonym Protein Names   
EndoCAM; GPIIA'; PECA1; CD_antigen: CD31
 UniProt Gene Name    PECAM1 [Similar Products]
 UniProt Synonym Gene Names    PECAM-1 [Similar Products]
 UniProt Entry Name    PECA1_HUMAN
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 NCBI Summary for PECAM1/CD31    The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
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 UniProt Comments for PECAM1/CD31    PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: extracellular space; platelet alpha granule membrane; integral to membrane; plasma membrane; cell junction

Molecular Function: protein binding

Biological Process: platelet activation; extracellular matrix organization and biogenesis; platelet degranulation; diapedesis; cell recognition; blood coagulation; signal transduction; cell adhesion; leukocyte migration; phagocytosis
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 Research Articles on PECAM1/CD31    1. PECAM is a sialic acid binding lectin and that this binding property supports endothelial cell survival.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PECAM1/CD31 elisa kitDiseases associated with PECAM1/CD31 elisa kit
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >630 publications with PECAM1/CD31 and Cardiovascular Diseases
 Inflammation Antibodies  >502 publications with PECAM1/CD31 and Inflammation
 Necrosis Antibodies  >404 publications with PECAM1/CD31 and Necrosis
 Neoplasms, Experimental Antibodies  >264 publications with PECAM1/CD31 and Neoplasms, Experimental
 Lung Diseases Antibodies  >246 publications with PECAM1/CD31 and Lung Diseases
 Heart Diseases Antibodies  >231 publications with PECAM1/CD31 and Heart Diseases
 Breast Neoplasms Antibodies  >209 publications with PECAM1/CD31 and Breast Neoplasms
 Lung Neoplasms Antibodies  >193 publications with PECAM1/CD31 and Lung Neoplasms
 Liver Diseases Antibodies  >179 publications with PECAM1/CD31 and Liver Diseases
 Liver Neoplasms Antibodies  >156 publications with PECAM1/CD31 and Liver Neoplasms
Organs/Tissues associated with PECAM1/CD31 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >3432 publications with PECAM1/CD31 and Vascular
 Blood Antibodies  >3024 publications with PECAM1/CD31 and Blood
 Muscle Antibodies  >690 publications with PECAM1/CD31 and Muscle
 Embryonic Tissue Antibodies  >511 publications with PECAM1/CD31 and Embryonic Tissue
 Lung Antibodies  >440 publications with PECAM1/CD31 and Lung
 Heart Antibodies  >355 publications with PECAM1/CD31 and Heart
 Skin Antibodies  >341 publications with PECAM1/CD31 and Skin
 Brain Antibodies  >325 publications with PECAM1/CD31 and Brain
 Connective Tissue Antibodies  >247 publications with PECAM1/CD31 and Connective Tissue
 Kidney Antibodies  >239 publications with PECAM1/CD31 and Kidney
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