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PKR2 elisa kit :: Human PKR2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2513123
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Human PKR2 (Prokineticin Receptor 2) ELISA Kit

 Product Gene Name   

PKR2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    244200
 3D Structure    ModBase 3D Structure for Q8NFJ6
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human PKR2. No significant cross-reactivity or interference between Human PKR2 and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human PKR2 and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.313-20ng/mL
 Sensitivity    Min: 0.188ng/mL; Max: 20ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PKR2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PKR2 purchase    MBS2513123 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PKR2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313-20ng/mL in biological research samples containing PKR2, with an estimated sensitivity of Min: 0.188ng/mL; Max: 20ng/mL. The ELISA analytical biochemical technique of the MBS2513123 kit is based on PKR2 antibody-PKR2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PKR2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PKR2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PKR2 elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of PKR2 in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human PKR2. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human PKR2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human PKR2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human PKR2. You can calculate the concentration of Human PKR2 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of PKR2 elisa kit    PKR2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2513123. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PKR2. It may not necessarily be applicable to this product.
 NCBI GI #    21426829
 NCBI GeneID    128674
 NCBI Accession #    NP_658986.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_144773.2 [Other Products]
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 UniProt Primary Accession #    Q8NFJ6 [Other Products]
 UniProt Secondary Accession #    Q2M3C0; Q5TDY1; Q9NTT0; A5JUU1 [Other Products]
 UniProt Related Accession #    Q8NFJ6 [Other Products]
 Molecular Weight    43,996 Da
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 NCBI Official Full Name    prokineticin receptor 2
 NCBI Official Synonym Full Names    prokineticin receptor 2
 NCBI Official Symbol    PROKR2 [Similar Products]
 NCBI Official Synonym Symbols   
HH3; KAL3; PKR2; GPRg2; GPR73b; GPR73L1; dJ680N4.3
[Similar Products]
 NCBI Protein Information    prokineticin receptor 2; G protein-coupled receptor 73-like 1; PK-R2
 UniProt Protein Name    Prokineticin receptor 2
 UniProt Synonym Protein Names   
G-protein coupled receptor 73-like 1; GPR73b; GPRg2
 UniProt Gene Name    PROKR2 [Similar Products]
 UniProt Synonym Gene Names    GPR73L1; PKR2; PK-R2 [Similar Products]
 UniProt Entry Name    PKR2_HUMAN
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 NCBI Summary for PKR2    Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor for prokineticins. The encoded protein is similar in sequence to GPR73, another G protein-coupled receptor for prokineticins. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PKR2    PROKR2: Receptor for prokineticin 2. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. Defects in PROKR2 are the cause of Kallmann syndrome type 3 (KAL3); also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin- releasing hormone-synthesizing neurons. KAL3 patients have variable degrees of olfactory and reproductive dysfunction, but do not show any of the occasional clinical anomalies reported in Kallmann syndrome such as renal agenesis, cleft lip and/or palate, selective tooth agenesis, and bimanual synkinesis. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR

Chromosomal Location of Human Ortholog: 20p12.3

Cellular Component: integral to membrane; plasma membrane

Molecular Function: neuropeptide Y receptor activity

Biological Process: circadian rhythm; neuropeptide signaling pathway

Disease: Hypogonadotropic Hypogonadism 3 With Or Without Anosmia
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 Research Articles on PKR2    1. Study corroborates the clinical relevance of the EG-VEGF system in human early pregnancy, and provides evidence for the gene-gene interactions of EG-VEGF and PROKR variants.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PKR2 elisa kitPathways associated with PKR2 elisa kit
 Reference Product  PubMed Publications
 PROK2 elisa kit  >86 publications with PKR2 and PROK2
 GNRHR elisa kit  >27 publications with PKR2 and GNRHR
 KISS1R elisa kit  >17 publications with PKR2 and KISS1R
 TAC3 elisa kit  >17 publications with PKR2 and TAC3
 PROK1 elisa kit  >17 publications with PKR2 and PROK1
 TACR3 elisa kit  >16 publications with PKR2 and TACR3
 GNRH1 elisa kit  >11 publications with PKR2 and GNRH1
 KISS1 elisa kit  >5 publications with PKR2 and KISS1
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Other Pathway antibodies  GPCRs, Other Pathway Diagram
 Gastrin-CREB Signalling Pathway Via PKC And MAPK antibodies  Gastrin-CREB Signalling Pathway Via PKC And MAPK Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
Diseases associated with PKR2 elisa kitOrgans/Tissues associated with PKR2 elisa kit
 Disease Name  Pubmed Publications
 Kallmann Syndrome Antibodies  >59 publications with PKR2 and Kallmann Syndrome
 Nervous System Diseases Antibodies  >17 publications with PKR2 and Nervous System Diseases
 Inflammation Antibodies  >4 publications with PKR2 and Inflammation
 Neurobehavioral Manifestations Antibodies  >2 publications with PKR2 and Neurobehavioral Manifestations
 Hypertension Antibodies  >2 publications with PKR2 and Hypertension
 Craniofacial Abnormalities Antibodies  >2 publications with PKR2 and Craniofacial Abnormalities
 Skin Neoplasms Antibodies  >2 publications with PKR2 and Skin Neoplasms
 Hypertrophy Antibodies  >1 publications with PKR2 and Hypertrophy
 Fetal Growth Retardation Antibodies  >1 publications with PKR2 and Fetal Growth Retardation
 Nerve Degeneration Antibodies  >1 publications with PKR2 and Nerve Degeneration
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >22 publications with PKR2 and Brain
 Muscle Antibodies  >5 publications with PKR2 and Muscle
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