NP_006228.3
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
42,697 Da
NCBI Official Full Name
POU domain, class 4, transcription factor 1
NCBI Official Synonym Full Names
POU class 4 homeobox 1
NCBI Protein Information
POU domain, class 4, transcription factor 1; brain-3A; homeobox/POU domain protein RDC-1; brain-specific homeobox/POU domain protein 3A
UniProt Protein Name
POU domain, class 4, transcription factor 1
UniProt Synonym Protein Names
Brain-specific homeobox/POU domain protein 3A; Brain-3A; Brn-3A; Homeobox/POU domain protein RDC-1; Oct-T1
UniProt Synonym Gene Names
UniProt Entry Name
PO4F1_HUMAN
NCBI Summary for POU4F1
This gene encodes a member of the POU-IV class of neural transcription factors. This protein is expressed in a subset of retinal ganglion cells and may be involved in the developing sensory nervous system. This protein may also promote the growth of cervical tumors. A translocation of this gene is associated with some adult acute myeloid leukemias. [provided by RefSeq, Mar 2012]
UniProt Comments for POU4F1
POU4F1: Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons. Belongs to the POU transcription factor family. Class- 4 subfamily.
Protein type: Transcription factor; DNA-binding; Cell development/differentiation
Chromosomal Location of Human Ortholog: 13q31.1
Cellular Component: neuron projection; nuclear chromatin
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding
Biological Process: transcription from RNA polymerase II promoter; trigeminal nerve development; central nervous system neuron differentiation; positive regulation of apoptosis; negative regulation of transcription from RNA polymerase II promoter; habenula development; peripheral nervous system neuron development; cell migration in hindbrain; proprioception during equilibrioception; regulation of neurogenesis; synaptogenesis; suckling behavior; axonogenesis; neuron fate specification; positive regulation of transcription from RNA polymerase II promoter; mesoderm development; negative regulation of neuron apoptosis; sensory system development
Research Articles on POU4F1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with POU4F1 elisa kit
Pathways associated with POU4F1 elisa kit
Diseases associated with POU4F1 elisa kit
Organs/Tissues associated with POU4F1 elisa kit
|