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PRDX1 elisa kit :: Human PRDX1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2502078
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PRDX1, ELISA Kit

★Popular Item★
 Also Known As   

Human PRDX1 (Peroxiredoxin 1) ELISA Kit

 Product Gene Name   

PRDX1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2502078 COA    COA PDF
 OMIM    176763
 3D Structure    ModBase 3D Structure for Q06830
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinantHumanPRDX1. No significant cross-reactivity or interference between HumanPRDX1 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    15.625-1000pg/mL
 Sensitivity    9.375pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PRDX1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PRDX1 purchase    MBS2502078 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PRDX1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.625-1000pg/mL in biological research samples containing PRDX1, with an estimated sensitivity of 9.375pg/mL. The ELISA analytical biochemical technique of the MBS2502078 kit is based on PRDX1 antibody-PRDX1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRDX1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRDX1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PRDX1 elisa kit

   Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanPRDX1concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to PRDX1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PRDX1and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PRDX1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of PRDX1.You can calculate the concentration of PRDX1in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of PRDX1 elisa kit    PRDX1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2502078. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PRDX1. It may not necessarily be applicable to this product.
 NCBI GI #    32455266
 NCBI GeneID    5052
 NCBI Accession #    NP_859048.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_181697.2 [Other Products]
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 UniProt Primary Accession #    Q06830 [Other Products]
 UniProt Secondary Accession #    P35703; Q2V576; Q5T154; Q5T155; B5BU26; D3DPZ8 [Other Products]
 UniProt Related Accession #    Q06830 [Other Products]
 Molecular Weight    22,110 Da
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 NCBI Official Full Name    peroxiredoxin-1
 NCBI Official Synonym Full Names    peroxiredoxin 1
 NCBI Official Symbol    PRDX1 [Similar Products]
 NCBI Official Synonym Symbols   
PAG; PAGA; PAGB; PRX1; PRXI; MSP23; NKEFA; TDPX2; NKEF-A
[Similar Products]
 NCBI Protein Information    peroxiredoxin-1; natural killer cell-enhancing factor A; natural killer-enhancing factor A; proliferation-associated gene A; proliferation-associated gene protein; thioredoxin peroxidase 2; thioredoxin-dependent peroxide reductase 2
 UniProt Protein Name    Peroxiredoxin-1
 UniProt Synonym Protein Names   
Natural killer cell-enhancing factor A; NKEF-A; Proliferation-associated gene protein; PAG; Thioredoxin peroxidase 2; Thioredoxin-dependent peroxide reductase 2
 Protein Family    Peroxiredoxin
 UniProt Gene Name    PRDX1 [Similar Products]
 UniProt Synonym Gene Names    PAGA; PAGB; TDPX2; NKEF-A; PAG [Similar Products]
 UniProt Entry Name    PRDX1_HUMAN
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 NCBI Summary for PRDX1    This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]
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 UniProt Comments for PRDX1    PRDX1: a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). May have a proliferative effect and play a role in cancer development or progression.

Protein type: Nuclear receptor co-regulator; EC 1.11.1.15; Oxidoreductase

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: extracellular space; peroxisomal matrix; mitochondrial matrix; cytoplasm; melanosome; nucleolus; cytosol; nucleus

Molecular Function: protein binding; protein homodimerization activity; peroxidase activity; thioredoxin peroxidase activity; heme binding

Biological Process: cell proliferation; regulation of stress-activated MAPK cascade; retinal homeostasis; erythrocyte homeostasis; response to reactive oxygen species; removal of superoxide radicals; hydrogen peroxide catabolic process; natural killer cell mediated cytotoxicity; skeletal development; regulation of NF-kappaB import into nucleus
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 Research Articles on PRDX1    1. MicroRNA-510 promotes cell and tumor growth by targeting peroxiredoxin1 in breast cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PRDX1 elisa kitPathways associated with PRDX1 elisa kit
 Reference Product  PubMed Publications
 MYC elisa kit  >9 publications with PRDX1 and MYC
 SRXN1 elisa kit  >6 publications with PRDX1 and SRXN1
 TXN elisa kit  >3 publications with PRDX1 and TXN
 TLR4 elisa kit  >2 publications with PRDX1 and TLR4
 MAP3K5 elisa kit  >1 publications with PRDX1 and MAP3K5
 UBC elisa kit  >1 publications with PRDX1 and UBC
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
Diseases associated with PRDX1 elisa kitOrgans/Tissues associated with PRDX1 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >34 publications with PRDX1 and Carcinoma
 Lung Diseases Antibodies  >21 publications with PRDX1 and Lung Diseases
 Inflammation Antibodies  >16 publications with PRDX1 and Inflammation
 Liver Diseases Antibodies  >14 publications with PRDX1 and Liver Diseases
 Lung Neoplasms Antibodies  >14 publications with PRDX1 and Lung Neoplasms
 Nervous System Diseases Antibodies  >11 publications with PRDX1 and Nervous System Diseases
 Necrosis Antibodies  >11 publications with PRDX1 and Necrosis
 Disease Models, Animal Antibodies  >11 publications with PRDX1 and Disease Models, Animal
 Lung Injury Antibodies  >8 publications with PRDX1 and Lung Injury
 Breast Neoplasms Antibodies  >8 publications with PRDX1 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >32 publications with PRDX1 and Blood
 Lung Antibodies  >27 publications with PRDX1 and Lung
 Liver Antibodies  >26 publications with PRDX1 and Liver
 Brain Antibodies  >20 publications with PRDX1 and Brain
 Vascular Antibodies  >17 publications with PRDX1 and Vascular
 Muscle Antibodies  >12 publications with PRDX1 and Muscle
 Kidney Antibodies  >10 publications with PRDX1 and Kidney
 Nerve Antibodies  >9 publications with PRDX1 and Nerve
 Heart Antibodies  >7 publications with PRDX1 and Heart
 Embryonic Tissue Antibodies  >6 publications with PRDX1 and Embryonic Tissue
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