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PSA elisa kit :: Human PSA ELISA Kit

Scan QR to view Datasheet Catalog #    MBS494521 PSA elisa kit
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 Product Name   


★Popular Item★
 Also Known As   


 Product Gene Name   

PSA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    176820
 3D Structure    ModBase 3D Structure for P07288
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 Species Reactivity    Human
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 Samples    Serum and plasma
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 Preparation and Storage    2 - 8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PSA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PSA purchase    MBS494521 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PSA, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PSA. The ELISA analytical biochemical technique of the MBS494521 kit is based on PSA antibody-PSA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PSA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PSA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum and plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PSA elisa kit

   Intended Uses||The Measles IgG Antibody ELISA Test Kit has been designed for the detection and the quantitative determination of specific IgG antibodies against Measles in serum and plasma. For in-vitro diagnostic use

Principle of the Assay: The Measles IgG antibody test kit is based on the principle of the enzyme immunoassay (EIA). Measles antigen is bound on the surface of the microtiter strips. Diluted patient serum or ready-to-use standards are pipetted into the wells of the microtiter plate. A binding between the IgG antibodies of the serum and the immobilized Measles antigen takes place. After a one hour incubation at room temperature, the plate is rinsed with diluted wash solution, in order to remove unbound material. Then ready-to-use anti-human-lgG peroxidase conjugate is added and incubated for 30 minutes. After a further washing step, the substrate (TMB) solution is pipetted and incubated for 20 minutes, inducing the evelopment of a blue dye in the wells. The color development is terminated by the addition of a stop solution, which changes the color from blue to yellow. The resulting dye is measured spectrophotometrically at the wavelength of 450 nm. The concentration of the IgG antibodies is directly proportional to the intensity of the color.
 Product Categories/Family for PSA elisa kit    Oncology; Research Assays; Assay Categories
Sample Manual Insert of MBS494521. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PSA. It may not necessarily be applicable to this product.
 NCBI GI #    4502173
 NCBI GeneID    354
 NCBI Accession #    NP_001639.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001648.2 [Other Products]
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 UniProt Primary Accession #    P07288 [Other Products]
 UniProt Secondary Accession #    Q15096; Q16272; Q86TG8; Q8IXI4; C9JXH3; G3V0H4; G3XAE3 [Other Products]
 UniProt Related Accession #    P07288 [Other Products]
 Molecular Weight    25,116 Da
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 NCBI Official Full Name    prostate-specific antigen isoform 1 preproprotein
 NCBI Official Synonym Full Names    kallikrein-related peptidase 3
 NCBI Official Symbol    KLK3 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    prostate-specific antigen; P-30 antigen; gamma-seminoprotein; kallikrein-3; prostate specific antigen; semenogelase; seminin
 UniProt Protein Name    Prostate-specific antigen
 UniProt Synonym Protein Names   
Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase
 Protein Family    PsaJ-like protein asl3190
 UniProt Gene Name    KLK3 [Similar Products]
 UniProt Synonym Gene Names    APS; PSA; Seminin [Similar Products]
 UniProt Entry Name    KLK3_HUMAN
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 NCBI Summary for PSA    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PSA    PSA: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum. Forms heterodimer with SERPINA5. Inhibited by SERPINA5. Activity is strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. Belongs to the peptidase S1 family. Kallikrein subfamily.

Protein type: Secreted; Secreted, signal peptide; Protease; EC

Chromosomal Location of Human Ortholog: 19q13.41

Cellular Component: extracellular region; nucleus

Molecular Function: protein binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: negative regulation of angiogenesis; cellular protein metabolic process; proteolysis
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 Research Articles on PSA    1. Suggest that the occurrence of PCa is related to the genotype of KLK3 SNPs rs2735839.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PSA elisa kitPathways associated with PSA elisa kit
 Reference Product  PubMed Publications
 TP53 elisa kit  >2 publications with PSA and TP53
 ERBB2 elisa kit  >2 publications with PSA and ERBB2
 IL6 elisa kit  >1 publications with PSA and IL6
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Coregulation Of Androgen Receptor Activity Pathway antibodies  Coregulation Of Androgen Receptor Activity Pathway Diagram
 FOXA1 Transcription Factor Network Pathway antibodies  FOXA1 Transcription Factor Network Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
 Regulation Of Androgen Receptor Activity Pathway antibodies  Regulation Of Androgen Receptor Activity Pathway Diagram
 Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway antibodies  Regulation Of Insulin-like Growth Factor (IGF) Transport And Uptake By Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Diagram
Diseases associated with PSA elisa kitOrgans/Tissues associated with PSA elisa kit
 Disease Name  Pubmed Publications
 Prostatic Neoplasms Antibodies  >79 publications with PSA and Prostatic Neoplasms
 Adenocarcinoma Antibodies  >15 publications with PSA and Adenocarcinoma
 Breast Neoplasms Antibodies  >14 publications with PSA and Breast Neoplasms
 Disease Progression Antibodies  >10 publications with PSA and Disease Progression
 Hyperplasia Antibodies  >9 publications with PSA and Hyperplasia
 Prostatic Hyperplasia Antibodies  >9 publications with PSA and Prostatic Hyperplasia
 Ovarian Neoplasms Antibodies  >7 publications with PSA and Ovarian Neoplasms
 Kidney Diseases Antibodies  >6 publications with PSA and Kidney Diseases
 Neoplasm Metastasis Antibodies  >6 publications with PSA and Neoplasm Metastasis
 Neoplasms, Experimental Antibodies  >6 publications with PSA and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >143 publications with PSA and Prostate
 Brain Antibodies  >5 publications with PSA and Brain
 Bone Antibodies  >5 publications with PSA and Bone
 Salivary Gland Antibodies  >4 publications with PSA and Salivary Gland
 Muscle Antibodies  >2 publications with PSA and Muscle
 Bone Marrow Antibodies  >2 publications with PSA and Bone Marrow
 Nerve Antibodies  >2 publications with PSA and Nerve
 Adrenal Gland Antibodies  >1 publications with PSA and Adrenal Gland
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