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PTK7 elisa kit :: Human PTK7 protein tyrosine kinase 7 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS937713
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PTK7 protein tyrosine kinase 7, ELISA Kit

★Popular Item★
 Also Known As   

Human Inactive tyrosine-protein kinase 7, PTK7 ELISA Kit

 Product Synonym Names    Human Inactive tyrosine-protein kinase 7 (PTK7) ELISA kit; CCK4; colon carcinoma kinase-4; PTK7 protein tyrosine kinase 7
 Product Gene Name   

PTK7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS937713 Testing Data    Testing Data PDF
 OMIM    601890
 3D Structure    ModBase 3D Structure for Q13308
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human PTK7. No significant cross-reactivity or interference between human PTK7 and analogues was observed.
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 Samples    serum, plasma, tissue homogenates, cell lysates.
 Assay Type    Sandwich (Quantitative)
 Detection Range    12.5 pg/ml-800 pg/ml.
 Sensitivity    Typically less than 3.125 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTK7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTK7 purchase    MBS937713 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PTK7 protein tyrosine kinase 7, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 12.5 pg/ml-800 pg/ml in biological research samples containing PTK7, with an estimated sensitivity of Typically less than 3.125 pg/ml. The ELISA analytical biochemical technique of the MBS937713 kit is based on PTK7 antibody-PTK7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTK7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTK7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Typical Testing Data/Standard Curve (for reference only) of PTK7 elisa kit    PTK7 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS937713. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PTK7. It may not necessarily be applicable to this product.
 NCBI GI #    393715082
 NCBI GeneID    5754
 NCBI Accession #    NP_001257327.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001270398.1 [Other Products]
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 UniProt Primary Accession #    Q13308 [Other Products]
 UniProt Secondary Accession #    Q13417; Q5T650; Q6IQ54; Q8NFA5; Q8NFA6; Q8NFA7; Q8NFA8; A8K974; B7Z477; E9PFZ5 [Other Products]
 UniProt Related Accession #    Q13308 [Other Products]
 Molecular Weight    118,392 Da
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 NCBI Official Full Name    inactive tyrosine-protein kinase 7 isoform e
 NCBI Official Synonym Full Names    protein tyrosine kinase 7
 NCBI Official Symbol    PTK7 [Similar Products]
 NCBI Official Synonym Symbols   
CCK4; CCK-4
[Similar Products]
 NCBI Protein Information    inactive tyrosine-protein kinase 7; colon carcinoma kinase 4; PTK7 protein tyrosine kinase 7; tyrosine-protein kinase-like 7; pseudo tyrosine kinase receptor 7
 UniProt Protein Name    Inactive tyrosine-protein kinase 7
 UniProt Synonym Protein Names   
Colon carcinoma kinase 4; CCK-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7
 Protein Family    Inactive tyrosine-protein kinase
 UniProt Gene Name    PTK7 [Similar Products]
 UniProt Synonym Gene Names    CCK4; CCK-4 [Similar Products]
 UniProt Entry Name    PTK7_HUMAN
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 NCBI Summary for PTK7    This gene encodes a member of the receptor protein tyrosine kinase family of proteins that transduce extracellular signals across the cell membrane. The encoded protein lacks detectable catalytic tyrosine kinase activity, is involved in the Wnt signaling pathway and plays a role in multiple cellular processes including polarity and adhesion. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
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 UniProt Comments for PTK7    CCK4: Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis. Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Protein kinase, TK; Membrane protein, integral; Kinase, protein; EC 2.7.10.1; Protein kinase, tyrosine (receptor); TK group; CCK4 family

Chromosomal Location of Human Ortholog: 6p21.1-p12.2

Cellular Component: focal adhesion; integral to plasma membrane; intercellular junction

Molecular Function: protein binding; protein-tyrosine kinase activity; ATP binding

Biological Process: cell migration; peptidyl-tyrosine phosphorylation; wound healing; convergent extension; actin cytoskeleton reorganization; neural tube closure; establishment of epithelial cell polarity; establishment of planar polarity; Wnt receptor signaling pathway through beta-catenin; signal transduction; cell adhesion
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 Research Articles on PTK7    1. This work defines PTK7 as a highly and specifically expressed gene in adenocarcinoma and a potential therapeutic target in this subset of NSCLC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PTK7 elisa kitOrgans/Tissues associated with PTK7 elisa kit
 Disease Name  Pubmed Publications
 Neural Tube Defects Antibodies  >7 publications with PTK7 and Neural Tube Defects
 Leukopenia Antibodies  >1 publications with PTK7 and Leukopenia
 Central Nervous System Diseases Antibodies  >1 publications with PTK7 and Central Nervous System Diseases
 Bone Marrow Diseases Antibodies  >1 publications with PTK7 and Bone Marrow Diseases
 Intellectual Disability Antibodies  >1 publications with PTK7 and Intellectual Disability
 Abnormalities, Multiple Antibodies  >1 publications with PTK7 and Abnormalities, Multiple
 Syndrome Antibodies  >1 publications with PTK7 and Syndrome
 Brain Diseases Antibodies  >1 publications with PTK7 and Brain Diseases
 Neoplasm Metastasis Antibodies  >1 publications with PTK7 and Neoplasm Metastasis
 Abnormalities, Drug-Induced Antibodies  >1 publications with PTK7 and Abnormalities, Drug-Induced
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >11 publications with PTK7 and Brain
 Lung Antibodies  >8 publications with PTK7 and Lung
 Embryonic Tissue Antibodies  >7 publications with PTK7 and Embryonic Tissue
 Blood Antibodies  >5 publications with PTK7 and Blood
 Bone Antibodies  >4 publications with PTK7 and Bone
 Liver Antibodies  >4 publications with PTK7 and Liver
 Stomach Antibodies  >3 publications with PTK7 and Stomach
 Thymus Antibodies  >3 publications with PTK7 and Thymus
 Vascular Antibodies  >3 publications with PTK7 and Vascular
 Pancreas Antibodies  >2 publications with PTK7 and Pancreas
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