Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow PTPRK rightarrow Human PTPRK  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Luciferase Antibody
 • CD5 Antigen-like (CD5L) ELISA Kit
 • HSL Antibody
 • HeLa Slide
 • Micrococcus luteus Polynucleotide phosphorylase Antibody
 • Beta-amyloid protein 42 (Beta-APP42) ELISA Kit
 • NGAL ELISA Kit
 • IgG (H&L) (min x Rat, Human, Bov, Hrs, Rabbit) Antibody
 • MMP-13 ELISA Kit
 • Bisphosphoglycerate Mutase (BPGM) ELISA Kit
 • Adaptin ear-binding coat-associated protein 1 (Necap1) Recombinant Protein
 • KLK3 Antibody
 • PGHS-1 Protein
 • IgG Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

PTPRK elisa kit :: Human PTPRK ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2509443
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PTPRK, ELISA Kit

★Popular Item★
 Also Known As   

Human PTPRK (Protein Tyrosine Phosphatase Receptor Type K) ELISA Kit

 Product Gene Name   

PTPRK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    602545
 3D Structure    ModBase 3D Structure for Q15262
Section Bar
 Species Reactivity    Human
Section Bar
 Specificity    This kit recognizes natural and recombinant Human PTPRK. No significant cross-reactivity or interference between Human PTPRK and analogues was observed.
Section Bar
 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
Section Bar
 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTPRK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTPRK purchase    MBS2509443 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PTPRK, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing PTPRK, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2509443 kit is based on PTPRK antibody-PTPRK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTPRK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTPRK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Related Product Information for PTPRK elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human PTPRK concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to PTPRK. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for PTPRK and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain PTPRK, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of PTPRK. You can calculate the concentration of PTPRK in the samples by comparing the OD of the samples to the standard curve.
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of PTPRK elisa kit    PTPRK elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS2509443. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for PTPRK. It may not necessarily be applicable to this product.
 NCBI GI #    219519675
 NCBI GeneID    5796
 NCBI Accession #    AAI44514.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q15262 [Other Products]
 UniProt Secondary Accession #    Q14763; Q5TG10; Q5TG11; B2RTQ8; B7ZMG0 [Other Products]
 UniProt Related Accession #    Q15262 [Other Products]
 Molecular Weight    164,613 Da
Table BarTOPTable Bar
 NCBI Official Full Name    PTPRK protein
 NCBI Official Synonym Full Names    protein tyrosine phosphatase, receptor type, K
 NCBI Official Symbol    PTPRK [Similar Products]
 NCBI Official Synonym Symbols   
R-PTP-kappa
[Similar Products]
 NCBI Protein Information    receptor-type tyrosine-protein phosphatase kappa; dJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa , protein tyrosine phosphatase kappa; protein-tyrosine phosphatase kappa; protein-tyrosine phosphatase, receptor type, kappa
 UniProt Protein Name    Receptor-type tyrosine-protein phosphatase kappa
 Protein Family    Receptor-type tyrosine-protein phosphatase
 UniProt Gene Name    PTPRK [Similar Products]
 UniProt Synonym Gene Names    PTPK; Protein-tyrosine phosphatase kappa; R-PTP-kappa [Similar Products]
 UniProt Entry Name    PTPRK_HUMAN
Section Bar
 NCBI Summary for PTPRK    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for PTPRK    PTPRK: a receptor tyrosine phosphatase involved in processes including cell contact and adhesion, growth, tumor invasion, and metastasis. Is a negative regulator of EGFR signaling. Forms complexes with beta-catenin and gamma-catenin, and may modulate the phosphorylation status of beta-catenin. Absent or down-regulated in multiple melanoma cell lines and some melanoma tumors. The gene lies in a region frequently deleted in hematological neoplasms, melanomas, ovary carcinomas, and many other solid tumors. Can play a dual role of tumor suppressor and tumor promoter in mammary epithelial cells. Overexpression results in inhibition of basal proliferation and EGFR signaling in cancer cells. A key regulator of EGFR tyrosine phosphorylation and function in human keratinocytes. TGF-beta 1 stimulates its expression, which may be important for the inhibition of keratinocyte proliferation. Belongs to the protein-tyrosine phosphatase family, receptor class 2B subfamily. Four isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor protein phosphatase, tyrosine; EC 3.1.3.48; Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 6q22.2-q22.3

Cellular Component: cell surface; adherens junction; photoreceptor outer segment; cell soma; integral to plasma membrane; axon; dendrite; integral to membrane; intercellular junction

Molecular Function: protein binding; gamma-catenin binding; beta-catenin binding; transmembrane receptor protein tyrosine phosphatase activity; protein tyrosine phosphatase activity; protein kinase binding

Biological Process: focal adhesion formation; negative regulation of cell proliferation; cell migration; transforming growth factor beta receptor signaling pathway; cell adhesion; signal transduction; protein amino acid dephosphorylation; negative regulation of transcription, DNA-dependent; negative regulation of cell migration; negative regulation of cell cycle
Table BarTOPTable Bar
 Research Articles on PTPRK    1. PTPRK showed lower mRNA expression in duodenal mucose of celiac disease patients.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with PTPRK elisa kitPathways associated with PTPRK elisa kit
 Reference Product  PubMed Publications
 EGFR elisa kit  >9 publications with PTPRK and EGFR
 CTNNB1 elisa kit  >5 publications with PTPRK and CTNNB1
 PTPRM elisa kit  >4 publications with PTPRK and PTPRM
 ERBB2 elisa kit  >3 publications with PTPRK and ERBB2
 SMAD2 elisa kit  >1 publications with PTPRK and SMAD2
 Products by Pathway  Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
Diseases associated with PTPRK elisa kitOrgans/Tissues associated with PTPRK elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >3 publications with PTPRK and Carcinoma
 Neoplasms, Experimental Antibodies  >3 publications with PTPRK and Neoplasms, Experimental
 Nervous System Diseases Antibodies  >3 publications with PTPRK and Nervous System Diseases
 Breast Neoplasms Antibodies  >3 publications with PTPRK and Breast Neoplasms
 Melanoma Antibodies  >3 publications with PTPRK and Melanoma
 Adenocarcinoma Antibodies  >2 publications with PTPRK and Adenocarcinoma
 Inflammation Antibodies  >2 publications with PTPRK and Inflammation
 Prostatic Neoplasms Antibodies  >2 publications with PTPRK and Prostatic Neoplasms
 Lung Neoplasms Antibodies  >1 publications with PTPRK and Lung Neoplasms
 Necrosis Antibodies  >1 publications with PTPRK and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >6 publications with PTPRK and Brain
 Bone Antibodies  >5 publications with PTPRK and Bone
 Thymus Antibodies  >4 publications with PTPRK and Thymus
 Lung Antibodies  >4 publications with PTPRK and Lung
 Kidney Antibodies  >2 publications with PTPRK and Kidney
 Prostate Antibodies  >2 publications with PTPRK and Prostate
 Connective Tissue Antibodies  >1 publications with PTPRK and Connective Tissue
 Mammary Gland Antibodies  >1 publications with PTPRK and Mammary Gland
 Skin Antibodies  >1 publications with PTPRK and Skin
 Esophagus Antibodies  >1 publications with PTPRK and Esophagus
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions