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PTX3 elisa kit :: Human PTX3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS825009
 Typical Testing Data/Standard Curve (for reference only)
Unit / Price
96 Tests  /  $470 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

PTX3, ELISA Kit

★Popular Item★
 Also Known As   

Human PTX3 ELISA Kit

 Product Synonym Names    TNFAIP5; TSG14; Pentraxin-related protein PTX3; Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14
 Product Gene Name   

PTX3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    602492
 3D Structure    ModBase 3D Structure for P26022
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 Species Reactivity    Human
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 Specificity    The Human PTX3 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human PTX3 proteins within the range of 312 pg/ml - 20000 pg/ml.
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 Samples    Cell Culture Supernatants, Serum, Plasma
 Assay Type    Quantitative Sandwich
 Sensitivity    <10 pg/ml.
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 Preparation and Storage    Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTX3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTX3 purchase    MBS825009 is a ready-to-use microwell, strip-or-full plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the PTX3, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTX3, with an estimated sensitivity of <10 pg/ml. The ELISA analytical biochemical technique of the MBS825009 kit is based on PTX3 antibody-PTX3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTX3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTX3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Cell Culture Supernatants, Serum, Plasma. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PTX3 elisa kit

   Principle of the Assay: MBS Human PTX3 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Human PTX3 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Human PTX3 coated on a 96-well plate. Standards and samples are pipetted into the wells and PTX3 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Human PTX3 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of PTX3 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.

Background: PTX3 (Pentraxin 3) is a member of the pentraxin superfamily. This super family characterized by cyclic multimeric structure. The PTX3 gene is mapped to 3q25.32. The predicted 381-amino acid PTX3 protein has homology to the pentraxin protein family. Significant levels of PTX3 were detected in plasma of neutropenic patients with systemic A. PTX3 is effective in preventing CMV infection and reactivation, as well as subsequent Aspergillus infection. PTX3 activates the classical pathway of complementactivation and facilitates pathogen recognition by macrophages and DCs.
 Applications Tested/Suitable for PTX3 elisa kit   

Sandwich ELISA (SE)

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  Typical Testing Data/Standard Curve (for reference only) of PTX3 elisa kit    PTX3 elisa kit  Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS825009. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PTX3. It may not necessarily be applicable to this product.
 NCBI GI #    167900484
 NCBI GeneID    5806
 NCBI Accession #    NP_002843.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_002852.3 [Other Products]
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 UniProt Primary Accession #    P26022 [Other Products]
 UniProt Secondary Accession #    Q38M82; B2R6T6 [Other Products]
 UniProt Related Accession #    P26022 [Other Products]
 Molecular Weight    41,976 Da
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 NCBI Official Full Name    pentraxin-related protein PTX3
 NCBI Official Synonym Full Names    pentraxin 3, long
 NCBI Official Symbol    PTX3 [Similar Products]
 NCBI Official Synonym Symbols   
TSG-14; TNFAIP5
[Similar Products]
 NCBI Protein Information    pentraxin-related protein PTX3; pentraxin-3; TNF alpha-induced protein 5; pentaxin-related protein PTX3; tumor necrosis factor alpha-induced protein 5; tumor necrosis factor, alpha-induced protein 5; tumor necrosis factor-inducible protein TSG-14; tumor necrosis factor-inducible gene 14 protein; pentraxin-related gene, rapidly induced by IL-1 beta; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor, alpha-induced protein 5
 UniProt Protein Name    Pentraxin-related protein PTX3
 UniProt Synonym Protein Names   
Pentaxin-related protein PTX3; Tumor necrosis factor alpha-induced protein 5; TNF alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; TSG-14
 Protein Family    Pentraxin-related protein
 UniProt Gene Name    PTX3 [Similar Products]
 UniProt Synonym Gene Names    TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14 [Similar Products]
 UniProt Entry Name    PTX3_HUMAN
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 UniProt Comments for PTX3    PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q25

Cellular Component: extracellular space; extracellular region

Molecular Function: complement component C1q binding; zymosan binding; virion binding

Biological Process: positive regulation of nitric oxide biosynthetic process; negative regulation of virion penetration into host cell; positive regulation of phagocytosis; innate immune response; response to yeast; opsonization; inflammatory response
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 Research Articles on PTX3    1. In the early phase of acute pancreatitis (AP), the concentrations of PTX3 achieved maximum earlier than CRP or SAA, enabling to differentiate between mild, moderate or severe AP in the first day of the disease.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PTX3 elisa kitDiseases associated with PTX3 elisa kit
 Reference Product  PubMed Publications
 FGF2 elisa kit  >22 publications with PTX3 and FGF2
 IL1B elisa kit  >5 publications with PTX3 and IL1B
 C1S elisa kit  >3 publications with PTX3 and C1S
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >344 publications with PTX3 and Inflammation
 Necrosis Antibodies  >91 publications with PTX3 and Necrosis
 Atherosclerosis Antibodies  >78 publications with PTX3 and Atherosclerosis
 Heart Diseases Antibodies  >68 publications with PTX3 and Heart Diseases
 Kidney Diseases Antibodies  >45 publications with PTX3 and Kidney Diseases
 Myocardial Infarction Antibodies  >40 publications with PTX3 and Myocardial Infarction
 Nervous System Diseases Antibodies  >34 publications with PTX3 and Nervous System Diseases
 Heart Failure Antibodies  >30 publications with PTX3 and Heart Failure
 Disease Models, Animal Antibodies  >29 publications with PTX3 and Disease Models, Animal
 Skin Diseases Antibodies  >29 publications with PTX3 and Skin Diseases
Organs/Tissues associated with PTX3 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >156 publications with PTX3 and Vascular
 Heart Antibodies  >77 publications with PTX3 and Heart
 Brain Antibodies  >54 publications with PTX3 and Brain
 Lung Antibodies  >52 publications with PTX3 and Lung
 Kidney Antibodies  >52 publications with PTX3 and Kidney
 Liver Antibodies  >38 publications with PTX3 and Liver
 Muscle Antibodies  >37 publications with PTX3 and Muscle
 Bone Antibodies  >25 publications with PTX3 and Bone
 Connective Tissue Antibodies  >23 publications with PTX3 and Connective Tissue
 Embryonic Tissue Antibodies  >20 publications with PTX3 and Embryonic Tissue
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