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PAX8 elisa kit :: Human Paired box protein Pax-8 (PAX8) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9341150 PAX8 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
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 Product Name   

Paired box protein Pax-8 (PAX8), ELISA Kit

★Popular Item★
 Also Known As   

Human Paired box protein Pax-8 (PAX8) ELISA Kit

 Product Synonym Names    paired box 8; paired domain gene 8
 Product Gene Name   

PAX8 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 2; NC_000002.11 (113973574..114036498, complement). Location: 2q13
 OMIM    167415
 3D Structure    ModBase 3D Structure for Q06710
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    31.2 pg/ml - 1000 pg/ml.
 Sensitivity    5.0 pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PAX8 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PAX8 purchase    MBS9341150 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Paired box protein Pax-8 (PAX8) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2 pg/ml - 1000 pg/ml in biological research samples containing PAX8, with an estimated sensitivity of 5.0 pg/ml. The ELISA analytical biochemical technique of the MBS9341150 kit is based on PAX8 antibody-PAX8 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PAX8 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PAX8. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PAX8 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PAX8 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9341150. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PAX8. It may not necessarily be applicable to this product.
 NCBI GI #    5803117
 NCBI GeneID    7849
 NCBI Accession #    NP_003457.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003466.3 [Other Products]
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 UniProt Primary Accession #    Q06710 [Other Products]
 UniProt Secondary Accession #    Q09155; Q16337; Q16338; Q16339; Q4ZG35; Q96J49 [Other Products]
 UniProt Related Accession #    Q06710 [Other Products]
 Molecular Weight    48,218 Da
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 NCBI Official Full Name    paired box protein Pax-8 isoform PAX8A
 NCBI Official Synonym Full Names    paired box 8
 NCBI Official Symbol    PAX8 [Similar Products]
 NCBI Protein Information    paired box protein Pax-8; paired domain gene 8
 UniProt Protein Name    Paired box protein Pax-8
 Protein Family    Paired box protein
 UniProt Gene Name    PAX8 [Similar Products]
 UniProt Entry Name    PAX8_HUMAN
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 NCBI Summary for PAX8    This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2010]
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 UniProt Comments for PAX8    PAX8: Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. Interacts with WWTR1. Expressed in the excretory system, thyroid gland and Wilms tumors. 5 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2q13

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein binding; DNA binding; transcription factor activity; thyroid-stimulating hormone receptor activity

Biological Process: inner ear morphogenesis; anatomical structure morphogenesis; central nervous system development; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; pronephros development; regulation of apoptosis; ureteric bud branching; thyroid gland development; mesonephros development; positive regulation of transcription from RNA polymerase II promoter; kidney development; urogenital system development

Disease: Hypothyroidism, Congenital, Nongoitrous, 2
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 Research Articles on PAX8    1. PAX8 was expressed in 61% of cases. There was no association between PAX8 and tumor stage, optimal debulking and disease recurrence for ovarian serous carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PAX8 elisa kitPathways associated with PAX8 elisa kit
 Reference Product  PubMed Publications
 NKX2-1 elisa kit  >22 publications with PAX8 and NKX2-1
 WBP2 elisa kit  >1 publications with PAX8 and WBP2
 SMAD3 elisa kit  >1 publications with PAX8 and SMAD3
 ID2 elisa kit  >1 publications with PAX8 and ID2
 Products by Pathway  Pathway Diagram
 Id Signaling Pathway antibodies  Id Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Thyroid Cancer Pathway antibodies  Thyroid Cancer Pathway Diagram
 Thyroid Cancer Pathway antibodies  Thyroid Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
 Transcriptional Misregulation In Cancer Pathway antibodies  Transcriptional Misregulation In Cancer Pathway Diagram
Diseases associated with PAX8 elisa kitOrgans/Tissues associated with PAX8 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >234 publications with PAX8 and Neoplasms
 Thyroid cancer, follicular Antibodies  >95 publications with PAX8 and Thyroid cancer, follicular
 Kidney Diseases Antibodies  >41 publications with PAX8 and Kidney Diseases
 Nervous System Diseases Antibodies  >21 publications with PAX8 and Nervous System Diseases
 Breast Neoplasms Antibodies  >18 publications with PAX8 and Breast Neoplasms
 Lung Neoplasms Antibodies  >15 publications with PAX8 and Lung Neoplasms
 Hyperplasia Antibodies  >14 publications with PAX8 and Hyperplasia
 Lung Diseases Antibodies  >13 publications with PAX8 and Lung Diseases
 Disease Models, Animal Antibodies  >11 publications with PAX8 and Disease Models, Animal
 Pancreatic Neoplasms Antibodies  >10 publications with PAX8 and Pancreatic Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >365 publications with PAX8 and Thyroid
 Kidney Antibodies  >96 publications with PAX8 and Kidney
 Brain Antibodies  >43 publications with PAX8 and Brain
 Lung Antibodies  >26 publications with PAX8 and Lung
 Eye Antibodies  >16 publications with PAX8 and Eye
 Ovary Antibodies  >13 publications with PAX8 and Ovary
 Lymph Node Antibodies  >13 publications with PAX8 and Lymph Node
 Bladder Antibodies  >12 publications with PAX8 and Bladder
 Pancreas Antibodies  >10 publications with PAX8 and Pancreas
 Testis Antibodies  >8 publications with PAX8 and Testis
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