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SPG7 elisa kit :: Human Paraplegin (SPG7) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9394847 SPG7 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Paraplegin (SPG7), ELISA Kit

★Popular Item★
 Also Known As   

Human Paraplegin (SPG7) ELISA Kit

 Product Gene Name   

SPG7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    Y16610 mRNA
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SPG7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SPG7 purchase    MBS9394847 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Paraplegin (SPG7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SPG7. The ELISA analytical biochemical technique of the MBS9394847 kit is based on SPG7 antibody-SPG7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SPG7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SPG7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for SPG7. It may not necessarily be applicable to this product.
 NCBI GI #    3273089
 NCBI Accession #    CAA76314.1 [Other Products]
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 UniProt Secondary Accession #    O75756; Q2TB70; Q58F00; Q96IB0 [Other Products]
 Molecular Weight    53,940 Da
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 NCBI Official Full Name    paraplegin
 UniProt Protein Name    Paraplegin
 UniProt Synonym Protein Names   
Spastic paraplegia 7 protein
 Protein Family    Paraplegin
 UniProt Gene Name    SPG7 [Similar Products]
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 UniProt Comments for SPG7    SPG7: Putative ATP-dependent zinc metalloprotease. Defects in SPG7 are the cause of spastic paraplegia autosomal recessive type 7 (SPG7). Spastic paraplegia is a degenerative spinal cord disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. SPG7 is a complex form. Additional clinical features are cerebellar syndrome, supranuclear palsy, and cognitive impairment, particularly disturbance of attention and executive functions. Defects in SPG7 may cause autosomal recessive osteogenesis imperfecta (OI). Osteogenesis imperfecta defines a group of connective tissue disorders characterized by bone fragility and low bone mass. Clinical features of SPG7-related osteogenesis imperfecta include recurrent fractures, mild bone deformities, delayed tooth eruption, normal hearing and white sclera. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Chaperone; EC 3.4.24.-; Membrane protein, integral; Membrane protein, multi-pass; Mitochondrial; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: mitochondrion

Molecular Function: ATP-dependent peptidase activity; metalloendopeptidase activity; peptidase activity; protein binding; unfolded protein binding

Biological Process: cell adhesion; mitochondrion organization and biogenesis; nervous system development

Disease: Spastic Paraplegia 7, Autosomal Recessive
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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