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PTHRP elisa kit :: Human Parathyroid Hormone Related Protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS017831 PTHRP elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Parathyroid Hormone Related Protein (PTHRP), ELISA Kit

★Popular Item★
 Also Known As   

Human Parathyroid Hormone Related Protein ELISA Kit

 Product Gene Name   

PTHRP elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 12; NC_000012.11 (28111017..28124916, complement). Location: 12p12.1-p11.2
 OMIM    168470
 3D Structure    ModBase 3D Structure for P12272
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    31.2 pg/ml - 1000 pg/ml.
 Sensitivity    5.0 pg/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTHRP elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTHRP purchase    MBS017831 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Parathyroid Hormone Related Protein (PTHRP) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 31.2 pg/ml - 1000 pg/ml in biological research samples containing PTHRP, with an estimated sensitivity of 5.0 pg/ml. The ELISA analytical biochemical technique of the MBS017831 kit is based on PTHRP antibody-PTHRP antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTHRP antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTHRP. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PTHRP elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PTHRP (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS017831. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PTHRP. It may not necessarily be applicable to this product.
 NCBI GI #    39995093
 NCBI GeneID    5744
 NCBI Accession #    NP_945317.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_198966.1 [Other Products]
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 UniProt Primary Accession #    P12272 [Other Products]
 UniProt Secondary Accession #    Q15251; Q6FH74 [Other Products]
 UniProt Related Accession #    P12272 [Other Products]
 Molecular Weight    20,194 Da
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 NCBI Official Full Name    parathyroid hormone-related protein isoform 1 preproprotein
 NCBI Official Synonym Full Names    parathyroid hormone-like hormone
 NCBI Official Symbol    PTHLH [Similar Products]
 NCBI Official Synonym Symbols   
HHM; PLP; BDE2; PTHR; PTHRP
[Similar Products]
 NCBI Protein Information    parathyroid hormone-related protein; PTH-rP; osteostatin; PTH-related protein; parathyroid hormone-like related protein
 UniProt Protein Name    Parathyroid hormone-related protein
 UniProt Synonym Protein Names   
Parathyroid hormone-like protein; PLPCleaved into the following 3 chains:PTHrP[1-36]PTHrP[38-94]Osteostatin; Alternative name(s):; PTHrP[107-139]
 UniProt Gene Name    PTHLH [Similar Products]
 UniProt Synonym Gene Names    PTHRP; PTH-rP; PTHrP; PLP [Similar Products]
 UniProt Entry Name    PTHR_HUMAN
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 NCBI Summary for PTHRP    The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PTHRP    PTHrP: a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Three alternatively spliced isoforms have been described.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12p12.1-p11.2

Cellular Component: nucleoplasm; Golgi apparatus; extracellular space; cytoplasm; extracellular region

Molecular Function: peptide hormone receptor binding; hormone activity

Biological Process: epidermis development; negative regulation of transcription factor activity; negative regulation of chondrocyte differentiation; female pregnancy; G-protein signaling, adenylate cyclase activating pathway; osteoblast development; negative regulation of cell proliferation; cAMP metabolic process; epithelial cell differentiation; cell-cell signaling; regulation of gene expression; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation; protein processing; alveolus development; skeletal development; surfactant homeostasis; endochondral ossification; endoderm development

Disease: Brachydactyly, Type E2
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 Research Articles on PTHRP    1. PTHrP increases the promoter activity of the integrin alpha6 and beta4 subunits.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PTHRP elisa kitPathways associated with PTHRP elisa kit
 Reference Product  PubMed Publications
 IHH elisa kit  >20 publications with PTHRP and IHH
 PTH1R elisa kit  >14 publications with PTHRP and PTH1R
 IL6 elisa kit  >2 publications with PTHRP and IL6
 PTH2R elisa kit  >2 publications with PTHRP and PTH2R
 PTCH1 elisa kit  >1 publications with PTHRP and PTCH1
 Products by Pathway  Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 G Alpha (s) Signalling Events Pathway antibodies  G Alpha (s) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Signaling Events Mediated By The Hedgehog Family Pathway antibodies  Signaling Events Mediated By The Hedgehog Family Pathway Diagram
Diseases associated with PTHRP elisa kitOrgans/Tissues associated with PTHRP elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >739 publications with PTHRP and Neoplasms
 Hypercalcemia Antibodies  >610 publications with PTHRP and Hypercalcemia
 Bone Resorption Antibodies  >139 publications with PTHRP and Bone Resorption
 Breast Neoplasms Antibodies  >122 publications with PTHRP and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >112 publications with PTHRP and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >102 publications with PTHRP and Lung Neoplasms
 Lung Diseases Antibodies  >88 publications with PTHRP and Lung Diseases
 Kidney Diseases Antibodies  >67 publications with PTHRP and Kidney Diseases
 Necrosis Antibodies  >48 publications with PTHRP and Necrosis
 Liver Neoplasms Antibodies  >46 publications with PTHRP and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Parathyroid Antibodies  >1195 publications with PTHRP and Parathyroid
 Kidney Antibodies  >144 publications with PTHRP and Kidney
 Lung Antibodies  >128 publications with PTHRP and Lung
 Skin Antibodies  >71 publications with PTHRP and Skin
 Embryonic Tissue Antibodies  >59 publications with PTHRP and Embryonic Tissue
 Prostate Antibodies  >43 publications with PTHRP and Prostate
 Uterus Antibodies  >32 publications with PTHRP and Uterus
 Mammary Gland Antibodies  >31 publications with PTHRP and Mammary Gland
 Brain Antibodies  >28 publications with PTHRP and Brain
 Pancreas Antibodies  >25 publications with PTHRP and Pancreas
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