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PRDX3 elisa kit :: Human Peroxiredoxin 3 (PRDX3) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2601074
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $260 +1 FREE 8GB USB
96-Strip-Wells  /  $405 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Peroxiredoxin 3 (PRDX3), ELISA Kit

★Popular Item★
 Also Known As   

Human Peroxiredoxin 3 (PRDX3) ELISA Kit

 Product Gene Name   

PRDX3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    604769
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 Species Reactivity    Human
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 Specificity    No cross-reaction with other factors.
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 Samples    Serum, plasma or cell culture supernatant
 Assay Type    Quantitative Sandwich
 Detection Range    200 ng/ml-0.312 ng/ml
 Sensitivity    Up to 0.06 ng/ml.
 Intra-assay Precision    <= 8%
 Inter-assay Precision    <= 12%
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PRDX3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PRDX3 purchase    MBS2601074 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Peroxiredoxin 3 (PRDX3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 200 ng/ml-0.312 ng/ml in biological research samples containing PRDX3, with an estimated sensitivity of Up to 0.06 ng/ml. The ELISA analytical biochemical technique of the MBS2601074 kit is based on PRDX3 antibody-PRDX3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PRDX3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PRDX3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma or cell culture supernatant. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PRDX3 elisa kit

   Principle of the Assay: This experiment use double-sandwich elisa technique and the ELISA Kit provided is typical. The pre-coated antibody is human PRDX3 monoclonal antibody and the detecting antibody is polyclonal antibody with biotin labeled. Samples and biotin labeling antibody are added into ELISA plate wells and washed out with PBS or TBS. Then Avidin-peroxidase conjugates are added to ELISA wells in order; Use TMB substrate for coloring after reactant thoroughly washed out by PBS or TBS. TMB turns into blue in peroxidase catalytic and finally turns into yellow under the action of acid. The color depth and the testing factors in samples are positively correlated.
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 Typical Standard Curve/Testing Data of PRDX3 elisa kit    PRDX3 elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS2601074. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PRDX3. It may not necessarily be applicable to this product.
 NCBI GI #    114205468
 NCBI GeneID    10935
 NCBI Accession #    AAI11398.1 [Other Products]
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 UniProt Secondary Accession #    P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4; B2R7Z0; D3DRC9; E9PH29 [Other Products]
 UniProt Related Accession #    P30048 [Other Products]
 Molecular Weight    25,839 Da
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 NCBI Official Full Name    Peroxiredoxin 3
 NCBI Official Synonym Full Names    peroxiredoxin 3
 NCBI Official Symbol    PRDX3 [Similar Products]
 NCBI Official Synonym Symbols   
AOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III
[Similar Products]
 NCBI Protein Information    thioredoxin-dependent peroxide reductase, mitochondrial; peroxiredoxin-3; peroxiredoxin III; protein MER5 homolog; antioxidant protein 1
 UniProt Protein Name    Thioredoxin-dependent peroxide reductase, mitochondrial
 UniProt Synonym Protein Names   
Antioxidant protein 1; AOP-1; HBC189; Peroxiredoxin III; Prx-III; Peroxiredoxin-3; Protein MER5 homolog
 Protein Family    Thioredoxin-dependent peroxide reductase
 UniProt Gene Name    PRDX3 [Similar Products]
 UniProt Synonym Gene Names    AOP1; AOP-1; Prx-III [Similar Products]
 UniProt Entry Name    PRDX3_HUMAN
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 NCBI Summary for PRDX3    This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation, differentiation, and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PRDX3    PRDX3: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Belongs to the AhpC/TSA family.

Protein type: Oxidoreductase; EC 1.11.1.15

Chromosomal Location of Human Ortholog: 10q25-q26

Cellular Component: mitochondrion; mitochondrial matrix; early endosome; cytoplasm; IkappaB kinase complex; cytosol

Molecular Function: protein C-terminus binding; identical protein binding; protein binding; thioredoxin peroxidase activity; caspase inhibitor activity; alkyl hydroperoxide reductase activity; protein kinase binding; kinase binding

Biological Process: mitochondrion organization and biogenesis; negative regulation of kinase activity; response to lipopolysaccharide; negative regulation of caspase activity; activation of NF-kappaB transcription factor; response to reactive oxygen species; peptidyl-cysteine oxidation; regulation of mitochondrial membrane potential; response to hydrogen peroxide; hydrogen peroxide catabolic process; positive regulation of cell proliferation; myeloid cell differentiation; response to oxidative stress; negative regulation of apoptosis; maternal placenta development
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 Research Articles on PRDX3    1. Data indicate that engineered Prx2 and Prx3 variants C-terminal residues modulate the extent of hyperoxidation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PRDX3 elisa kitPathways associated with PRDX3 elisa kit
 Reference Product  PubMed Publications
 MYC elisa kit  >5 publications with PRDX3 and MYC
 MAX elisa kit  >3 publications with PRDX3 and MAX
 FANCG elisa kit  >2 publications with PRDX3 and FANCG
 IKBKB elisa kit  >1 publications with PRDX3 and IKBKB
 ATOX1 elisa kit  >1 publications with PRDX3 and ATOX1
 ABRA elisa kit  >1 publications with PRDX3 and ABRA
 RPS6KC1 elisa kit  >1 publications with PRDX3 and RPS6KC1
 Products by Pathway  Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
 Detoxification Of Reactive Oxygen Species Pathway antibodies  Detoxification Of Reactive Oxygen Species Pathway Diagram
 Selenium Pathway antibodies  Selenium Pathway Diagram
 Validated Targets Of C-MYC Transcriptional Activation Pathway antibodies  Validated Targets Of C-MYC Transcriptional Activation Pathway Diagram
Organs/Tissues associated with PRDX3 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >31 publications with PRDX3 and Blood
 Brain Antibodies  >16 publications with PRDX3 and Brain
 Liver Antibodies  >14 publications with PRDX3 and Liver
 Lung Antibodies  >9 publications with PRDX3 and Lung
 Heart Antibodies  >9 publications with PRDX3 and Heart
 Muscle Antibodies  >8 publications with PRDX3 and Muscle
 Prostate Antibodies  >6 publications with PRDX3 and Prostate
 Nerve Antibodies  >6 publications with PRDX3 and Nerve
 Bone Antibodies  >6 publications with PRDX3 and Bone
 Vascular Antibodies  >6 publications with PRDX3 and Vascular
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