NP_083801.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
84,364 Da
NCBI Official Full Name
phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein isoform 1
NCBI Official Synonym Full Names
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
NCBI Official Synonym Symbols
Depdc2; P-Rex2; AI316880; AI553603; D430013K02; 6230420N16Rik; C030045D06Rik [Similar Products]
NCBI Protein Information
phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
UniProt Protein Name
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein
UniProt Synonym Protein Names
DEP domain-containing protein 2
UniProt Synonym Gene Names
UniProt Entry Name
PREX2_MOUSE
UniProt Comments for PREX2
PREX2: Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein- coupled receptors and phosphoinositide 3-kinase. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Phosphatase, regulatory subunit; GEFs, Rac/Rho; GEFs
Cellular Component: plasma membrane
Molecular Function: GTPase activator activity; guanyl-nucleotide exchange factor activity; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity
Biological Process: adult locomotory behavior; dendrite morphogenesis; G-protein coupled receptor protein signaling pathway; phosphoinositide 3-kinase cascade; positive regulation of GTPase activity; regulation of Rho protein signal transduction
Research Articles on PREX2
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with PREX2 elisa kit
Diseases associated with PREX2 elisa kit
Organs/Tissues associated with PREX2 elisa kit
|