NP_001119603.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
139,562 Da
NCBI Official Full Name
DNA polymerase subunit gamma-1
NCBI Official Synonym Full Names
DNA polymerase gamma, catalytic subunit
NCBI Official Synonym Symbols
PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B [Similar Products]
NCBI Protein Information
DNA polymerase subunit gamma-1
UniProt Protein Name
DNA polymerase subunit gamma-1
UniProt Synonym Protein Names
Mitochondrial DNA polymerase catalytic subunit; PolG-alpha
UniProt Synonym Gene Names
NCBI Summary for POLg1
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for POLg1
Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
Research Articles on POLg1
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Products associated with POLg1 elisa kit
Pathways associated with POLg1 elisa kit
Diseases associated with POLg1 elisa kit
Organs/Tissues associated with POLg1 elisa kit
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