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PTBP2 elisa kit :: Human Polypyrimidine tract-binding protein 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS280521 PTBP2 elisa kit
Unit / Price
48-Strip-Wells  /  $425 +1 FREE 8GB USB
96-Strip-Wells  /  $720 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,160 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,055 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Polypyrimidine tract-binding protein 2 (PTBP2), ELISA Kit

 Also Known As   

Human Polypyrimidine tract-binding protein 2 (PTBP2) ELISA Kit

 Product Gene Name   

PTBP2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    AF176085 mRNA
 3D Structure    ModBase 3D Structure for Q9UKA9
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human PTBP2. No significant cross-reactivity or interference between Human PTBP2 and analogues was observed.
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 Samples    Serum, Plasma, Other biological fluids
 Assay Type    Sandwich
 Sample Volume    1-200 uL
 Precision    Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
 Detection Wavelength    450 nm
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 Preparation and Storage    Store at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PTBP2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PTBP2 purchase    MBS280521 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Polypyrimidine tract-binding protein 2 (PTBP2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTBP2. The ELISA analytical biochemical technique of the MBS280521 kit is based on PTBP2 antibody-PTBP2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTBP2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTBP2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PTBP2 elisa kit

   Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate PTBP2 in samples. An antibody specific for PTBP2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPTBP2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PTBP2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PTBP2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI/Uniprot data below describe general gene information for PTBP2. It may not necessarily be applicable to this product.
 NCBI GI #    665821280
 NCBI GeneID    58155
 NCBI Accession #    NP_001287914.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001300985.1 [Other Products]
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 UniProt Primary Accession #    Q9UKA9 [Other Products]
 UniProt Secondary Accession #    Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76 [Other Products]
 UniProt Related Accession #    Q9UKA9 [Other Products]
 Molecular Weight    38,336 Da
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 NCBI Official Full Name    polypyrimidine tract-binding protein 2 isoform 1
 NCBI Official Synonym Full Names    polypyrimidine tract binding protein 2
 NCBI Official Symbol    PTBP2 [Similar Products]
 NCBI Official Synonym Symbols   
nPTB; PTBLP; brPTB
[Similar Products]
 NCBI Protein Information    polypyrimidine tract-binding protein 2
 UniProt Protein Name    Polypyrimidine tract-binding protein 2
 UniProt Synonym Protein Names   
Neural polypyrimidine tract-binding protein; Neurally-enriched homolog of PTB; PTB-like protein
 Protein Family    Polypyrimidine tract-binding protein
 UniProt Gene Name    PTBP2 [Similar Products]
 UniProt Synonym Gene Names    NPTB; PTB; PTBLP [Similar Products]
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 NCBI Summary for PTBP2    The protein encoded by this gene binds to intronic polypyrimidine clusters in pre-mRNA molecules and is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein (PTB) but most of its isoforms are expressed primarily in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
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 UniProt Comments for PTBP2    PTBP2: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre- mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA processing; RNA-binding

Chromosomal Location of Human Ortholog: 1p21.3

Cellular Component: cell soma; growth cone; spliceosomal complex

Molecular Function: mRNA binding; RNA binding

Biological Process: cerebellum development; mRNA splice site selection; negative regulation of RNA splicing; regulation of neural precursor cell proliferation; spinal cord development
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 Research Articles on PTBP2    1. It has been established that PTBP1 and PTBP2 are members of a family of cryptic exon repressors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PTBP2 elisa kitPathways associated with PTBP2 elisa kit
 Reference Product  PubMed Publications
 PTBP1 elisa kit  >13 publications with PTBP2 and PTBP1
 Products by Pathway  Pathway Diagram
 MRNA Processing Pathway antibodies  MRNA Processing Pathway Diagram
Diseases associated with PTBP2 elisa kitOrgans/Tissues associated with PTBP2 elisa kit
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >2 publications with PTBP2 and Adenocarcinoma
 Congenital Abnormalities Antibodies  >1 publications with PTBP2 and Congenital Abnormalities
 Mental Disorders Antibodies  >1 publications with PTBP2 and Mental Disorders
 Cardiovascular Diseases Antibodies  >1 publications with PTBP2 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >1 publications with PTBP2 and Disease Models, Animal
 Inflammation Antibodies  >1 publications with PTBP2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with PTBP2 and Brain
 Testis Antibodies  >4 publications with PTBP2 and Testis
 Bone Antibodies  >3 publications with PTBP2 and Bone
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