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PROCR elisa kit :: Human Protein C Receptor, Endothelial ELISA Kit

Scan QR to view Datasheet Catalog #    MBS721058
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells-(Competitive)  /  $470 +1 FREE 8GB USB
48-Strip-Wells-(Sandwich)  /  $470 +1 FREE 8GB USB
96-Strip-Wells-(Competitive)  /  $675 +1 FREE 8GB USB
96-Strip-Wells-(Sandwich)  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells-(Competitive)  /  $2,850 +3 FREE 8GB USB
5x96-Strip-Wells-(Sandwich)  /  $2,850 +3 FREE 8GB USB
10x96-Strip-Wells-(Competitive)  /  $5,340 +6 FREE 8GB USB
10x96-Strip-Wells-(Sandwich)  /  $5,340 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protein C Receptor, Endothelial (PROCR), ELISA Kit

 Also Known As   

Human Protein C Receptor, Endothelial ELISA Kit

 Product Gene Name   

PROCR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    600646
 3D Structure    ModBase 3D Structure for Q9UNN8
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 Species Reactivity    Human
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 Assay Type    Competitive or Sandwich
 Highest Standards    25ng/mL
 Concentration of Standards    Concentration of Standards
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of PROCR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PROCR purchase    MBS721058 is a ready-to-use microwell, strip plate Competitive or Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protein C Receptor, Endothelial (PROCR) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PROCR. The ELISA analytical biochemical technique of the MBS721058 kit is based on PROCR antibody-PROCR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PROCR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PROCR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for PROCR elisa kit    Cardiovascular
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 Typical Testing Data/Standard Curve (for reference only) of PROCR elisa kit    PROCR elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS721058
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NCBI/Uniprot data below describe general gene information for PROCR. It may not necessarily be applicable to this product.
 NCBI GI #    48146013
 NCBI Accession #    CAG33229.1 [Other Products]
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 UniProt Primary Accession #    Q9UNN8 [Other Products]
 UniProt Secondary Accession #    Q14218; Q6IB56; Q96CB3; Q9ULX1; B2RC04 [Other Products]
 Molecular Weight    26,671 Da
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 NCBI Official Full Name    PROCR
 UniProt Protein Name    Endothelial protein C receptor
 UniProt Synonym Protein Names   
Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201
 Protein Family    Endothelial protein C receptor
 UniProt Gene Name    PROCR [Similar Products]
 UniProt Synonym Gene Names    EPCR; APC receptor [Similar Products]
 UniProt Entry Name    EPCR_HUMAN
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 NCBI Summary for PROCR    The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]
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 UniProt Comments for PROCR    EPCR: a single-pass type I membrane protein. Binds activated protein C (APC), a serine protease that regulates thrombin (IIa) production. Plays a pivotal role in preventing blood coagulation through binding of activated protein C. Expressed strongly in the endothelial cells of arteries and veins in heart and lung, less intensely in capillaries in the lung and skin, and not at all in the endothelium of small vessels of the liver and kidney. The binding of APC to EPCR and PAR-1 increases invasion and chemotaxis.

Protein type: Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20q11.2

Cellular Component: centrosome; cell surface; focal adhesion; integral to plasma membrane; extracellular region; plasma membrane

Molecular Function: protein binding; receptor activity

Biological Process: antigen processing and presentation; immune response; negative regulation of coagulation; blood coagulation; leukocyte migration
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PROCR elisa kitDiseases associated with PROCR elisa kit
 Reference Product  PubMed Publications
 APC elisa kit  >73 publications with PROCR and APC
 THBD elisa kit  >8 publications with PROCR and THBD
 PROC elisa kit  >6 publications with PROCR and PROC
 CCL2 elisa kit  >3 publications with PROCR and CCL2
 CAV1 elisa kit  >3 publications with PROCR and CAV1
 F2R elisa kit  >2 publications with PROCR and F2R
 F2RL1 elisa kit  >1 publications with PROCR and F2RL1
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >79 publications with PROCR and Inflammation
 Cardiovascular Diseases Antibodies  >66 publications with PROCR and Cardiovascular Diseases
 Necrosis Antibodies  >31 publications with PROCR and Necrosis
 Nervous System Diseases Antibodies  >21 publications with PROCR and Nervous System Diseases
 Disease Models, Animal Antibodies  >13 publications with PROCR and Disease Models, Animal
 Heart Diseases Antibodies  >12 publications with PROCR and Heart Diseases
 Breast Neoplasms Antibodies  >9 publications with PROCR and Breast Neoplasms
 Kidney Diseases Antibodies  >8 publications with PROCR and Kidney Diseases
 Hemorrhage Antibodies  >7 publications with PROCR and Hemorrhage
 Lung Neoplasms Antibodies  >5 publications with PROCR and Lung Neoplasms
Organs/Tissues associated with PROCR elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >154 publications with PROCR and Blood
 Vascular Antibodies  >110 publications with PROCR and Vascular
 Lung Antibodies  >21 publications with PROCR and Lung
 Brain Antibodies  >13 publications with PROCR and Brain
 Bone Antibodies  >12 publications with PROCR and Bone
 Heart Antibodies  >11 publications with PROCR and Heart
 Kidney Antibodies  >10 publications with PROCR and Kidney
 Embryonic Tissue Antibodies  >9 publications with PROCR and Embryonic Tissue
 Muscle Antibodies  >9 publications with PROCR and Muscle
 Umbilical Cord Antibodies  >9 publications with PROCR and Umbilical Cord
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