NP_066295.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,284 Da
NCBI Official Full Name
protein SSX5 isoform a
NCBI Official Synonym Full Names
SSX family member 5
NCBI Protein Information
protein SSX5
UniProt Protein Name
Protein SSX5
NCBI Summary for SSX5
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. While some of the related SSX genes are involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas, this gene does not appear to be involved in such translocations. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2013]
UniProt Comments for SSX5
Ssxb8: Could act as a modulator of transcription. Belongs to the SSX family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cancer Testis Antigen (CTA)
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: nucleus
Molecular Function: nucleic acid binding; protein binding; transcription corepressor activity
Biological Process: regulation of transcription, DNA-templated; transcription, DNA-dependent
Research Articles on SSX5
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Diseases associated with SSX5 elisa kit
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