NP_001094077.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
50,707 Da
NCBI Official Full Name
protein Z-dependent protease inhibitor
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
NCBI Official Synonym Symbols
NCBI Protein Information
protein Z-dependent protease inhibitor; serpin A10; PZ-dependent protease inhibitor; serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
UniProt Protein Name
Protein Z-dependent protease inhibitor
UniProt Synonym Protein Names
Serpin A10
UniProt Synonym Gene Names
UniProt Entry Name
ZPI_HUMAN
NCBI Summary for ZPI
The protein encoded by this gene belongs to the serpin family. It is predominantly expressed in the liver and secreted in plasma. It inhibits the activity of coagulation factors Xa and XIa in the presence of protein Z, calcium and phospholipid. Mutations in this gene are associated with venous thrombosis. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, May 2010]
UniProt Comments for ZPI
SERPINA10: Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Belongs to the serpin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14q32.13
Cellular Component: extracellular space
Molecular Function: serine-type endopeptidase inhibitor activity; heparin binding
Biological Process: regulation of acrosome reaction; blood coagulation
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Products associated with ZPI elisa kit
Diseases associated with ZPI elisa kit
Organs/Tissues associated with ZPI elisa kit
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