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PR3AB elisa kit :: Human Proteinase 3 antibody ELISA Kit

Scan QR to view Datasheet Catalog #    MBS728775
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells-(Competitive)  /  $455 +1 FREE 8GB USB
48-Strip-Wells-(Sandwich)  /  $455 +1 FREE 8GB USB
96-Strip-Wells-(Competitive)  /  $660 +1 FREE 8GB USB
96-Strip-Wells-(Sandwich)  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells-(Competitive)  /  $2,925 +3 FREE 8GB USB
5x96-Strip-Wells-(Sandwich)  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells-(Competitive)  /  $5,490 +6 FREE 8GB USB
10x96-Strip-Wells-(Sandwich)  /  $5,490 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Proteinase 3 antibody (PR3AB), ELISA Kit

 Also Known As   

Human Proteinase 3 antibody ELISA Kit

 Product Gene Name   

PR3AB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    177020
 3D Structure    ModBase 3D Structure for P24158
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 Species Reactivity    Human
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive or Sandwich
 Detection Range    0.5-10ng/mL
 Sensitivity    0.1ng/mL
 Highest Standards    10ng/mL
 Concentration of Standards    Concentration of Standards
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PR3AB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PR3AB purchase    MBS728775 is a ready-to-use microwell, strip plate Competitive or Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Proteinase 3 antibody (PR3AB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.5-10ng/mL in biological research samples containing PR3AB, with an estimated sensitivity of 0.1ng/mL. The ELISA analytical biochemical technique of the MBS728775 kit is based on PR3AB antibody-PR3AB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PR3AB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PR3AB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for PR3AB elisa kit    Signal Transduction
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 Typical Testing Data/Standard Curve (for reference only) of PR3AB elisa kit    PR3AB elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS728775. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PR3AB. It may not necessarily be applicable to this product.
 NCBI GI #    1335280
 NCBI Accession #    CAA39203.1 [Other Products]
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 UniProt Primary Accession #    P24158 [Other Products]
 UniProt Secondary Accession #    P15637; P18078; Q4VB08; Q4VB09; Q6LBM7; Q6LBN2; Q9UD25; Q9UQD8 [Other Products]
 Molecular Weight    27,807 Da
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 NCBI Official Full Name    proteinase 3
 UniProt Protein Name    Myeloblastin
 UniProt Synonym Protein Names   
AGP7; C-ANCA antigen; Leukocyte proteinase 3; PR-3; PR3; Neutrophil proteinase 4; NP-4; P29; Wegener autoantigen
 UniProt Gene Name    PRTN3 [Similar Products]
 UniProt Synonym Gene Names    MBN; PR-3; PR3; NP-4 [Similar Products]
 UniProt Entry Name    PRTN3_HUMAN
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 UniProt Comments for PR3AB    PRTN3: Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters. Belongs to the peptidase S1 family. Elastase subfamily.

Protein type: EC; Protease; Cell cycle regulation

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: extracellular matrix; extracellular space; plasma membrane; cytosol

Molecular Function: enzyme binding; serine-type peptidase activity; serine-type endopeptidase activity

Biological Process: negative regulation of phagocytosis; collagen catabolic process; positive regulation of cell proliferation; proteolysis; blood coagulation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with PR3AB elisa kitOrgans/Tissues associated with PR3AB elisa kit
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >375 publications with PR3AB and Lung Diseases
 Inflammation Antibodies  >153 publications with PR3AB and Inflammation
 Kidney Diseases Antibodies  >122 publications with PR3AB and Kidney Diseases
 Necrosis Antibodies  >78 publications with PR3AB and Necrosis
 Disease Models, Animal Antibodies  >36 publications with PR3AB and Disease Models, Animal
 Brain Diseases Antibodies  >32 publications with PR3AB and Brain Diseases
 Lupus Erythematosus, Systemic Antibodies  >31 publications with PR3AB and Lupus Erythematosus, Systemic
 Intestinal Diseases Antibodies  >30 publications with PR3AB and Intestinal Diseases
 Fibrosis Antibodies  >30 publications with PR3AB and Fibrosis
 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Antibodies  >20 publications with PR3AB and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >643 publications with PR3AB and Blood
 Bone Marrow Antibodies  >26 publications with PR3AB and Bone Marrow
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