Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource rightarrow ELISA Kit rightarrow RABGEF1 rightarrow Human RABGEF1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • Papillomavirus 16 E6 Recombinant Protein
 • ChimCMV1 Recombinant Protein
 • ZNF18 Antibody
 • Vitamin D binding (VTDB) Native Protein
 • amyloid beta peptide 1-40 (Abeta1-40) ELISA Kit
 • Period Circadian Protein 2 (PER2) ELISA Kit
 • NTCP Antibody
 • galactosidase, beta 1 (GLB1) ELISA Kit
 • Sonic HedgeHog (mSHH) Recombinant Protein
 • Superoxide Dismutases (SOD) ELISA Kit
 • Hsd11b1 Antibody
 • deoxynucleotidyltransferase , terminal, interacting protein 2... ELISA Kit
 • Cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) ELISA Kit
 • PKC delta (pY52) (PRKCD) Antibody
 downarrow more ...
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

RABGEF1 elisa kit :: Human RAB guanine nucleotide exchange factor (GEF) 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9325962 RABGEF1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1), ELISA Kit

★Popular Item★
 Also Known As   

Human Rab5 GDP/GTP exchange factor, RABGEF1 ELISA Kit

 Product Synonym Names    Human Rab5 GDP/GTP exchange factor (RABGEF1) ELISA kit; FLJ32302; RABEX5; rabex-5; OTTHUMP00000210543; Rab5 GDP/GTP exchange factor; RAB guanine nucleotide exchange factor (GEF) 1
 Product Gene Name   

RABGEF1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    609700
 3D Structure    ModBase 3D Structure for Q9UJ41
Section Bar
 Species Reactivity    Human
Section Bar
 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
Section Bar
 Assay Type    Sandwich
 Detection Range    0.25 ng/ml - 8 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RABGEF1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RABGEF1 purchase    MBS9325962 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the RAB guanine nucleotide exchange factor (GEF) 1 (RABGEF1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 ng/ml - 8 ng/ml in biological research samples containing RABGEF1, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9325962 kit is based on RABGEF1 antibody-RABGEF1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RABGEF1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RABGEF1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar

Related Product Information for RABGEF1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RABGEF1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9325962. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for RABGEF1. It may not necessarily be applicable to this product.
 NCBI GI #    559098403
 NCBI GeneID    27342
 NCBI Accession #    NP_001273989.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001287060.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q9UJ41 [Other Products]
 UniProt Secondary Accession #    Q3HKR2; Q3HKR3; Q53FG0; B4DZM7 [Other Products]
 UniProt Related Accession #    Q9UJ41 [Other Products]
 Molecular Weight    79,371 Da
Table BarTOPTable Bar
 NCBI Official Full Name    rab5 GDP/GTP exchange factor isoform a
 NCBI Official Synonym Full Names    RAB guanine nucleotide exchange factor (GEF) 1
 NCBI Official Symbol    RABGEF1 [Similar Products]
 NCBI Official Synonym Symbols   
RAP1; RABEX5; rabex-5
[Similar Products]
 NCBI Protein Information    rab5 GDP/GTP exchange factor; rabaptin-5-associated exchange factor for Rab5
 UniProt Protein Name    Rab5 GDP/GTP exchange factor
 UniProt Synonym Protein Names   
RAP1; Rabaptin-5-associated exchange factor for Rab5; Rabex-5
 Protein Family    Rab5 GDP/GTP exchange factor
 UniProt Gene Name    RABGEF1 [Similar Products]
 UniProt Synonym Gene Names    RABEX5 [Similar Products]
 UniProt Entry Name    RABX5_HUMAN
Section Bar
 NCBI Summary for RABGEF1    RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM, Mar 2010]
Section Bar
 UniProt Comments for RABGEF1    RABGEF1: Rab effector protein acting as linker between gamma- adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. Interacts with RGS14; the interaction is GTP-dependent. Heterodimer with RABEP1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Interacts with RAB21, and with 100-fold lower affinity also with RAB22. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2. Interacts with ubiquitinated EGFR. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; GAPs, Rab

Chromosomal Location of Human Ortholog: 7q11.21

Cellular Component: recycling endosome; early endosome; vesicle

Molecular Function: protein binding; DNA binding; zinc ion binding; ubiquitin-protein ligase activity; Rab guanyl-nucleotide exchange factor activity; Rab GTPase binding

Biological Process: negative regulation of protein amino acid phosphorylation; negative regulation of mast cell degranulation; negative regulation of inflammatory response; protein ubiquitination; negative regulation of Ras protein signal transduction; negative regulation of receptor-mediated endocytosis; endocytosis; protein targeting to membrane; negative regulation of leukocyte migration
Table BarTOPTable Bar
 Research Articles on RABGEF1    1. RABEX-5 mRNA expression is a strong predictor of poor prognosis in prostate cancer patients treated by radical prostatectomy.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with RABGEF1 elisa kitDiseases associated with RABGEF1 elisa kit
 Reference Product  PubMed Publications
 RABEP1 elisa kit  >7 publications with RABGEF1 and RABEP1
 RAB33B elisa kit  >1 publications with RABGEF1 and RAB33B
 GGA1 elisa kit  >1 publications with RABGEF1 and GGA1
 Disease Name  Pubmed Publications
 Gastrointestinal Diseases Antibodies  >2 publications with RABGEF1 and Gastrointestinal Diseases
 Proteinuria Antibodies  >1 publications with RABGEF1 and Proteinuria
 Kidney Diseases Antibodies  >1 publications with RABGEF1 and Kidney Diseases
 Hyperplasia Antibodies  >1 publications with RABGEF1 and Hyperplasia
Organs/Tissues associated with RABGEF1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with RABGEF1 and Brain
 Lymph Node Antibodies  >1 publications with RABGEF1 and Lymph Node
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions