NP_001191385.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
12,251 Da
NCBI Official Full Name
RB-associated KRAB zinc finger protein
NCBI Official Synonym Full Names
RB-associated KRAB zinc finger
NCBI Official Synonym Symbols
NCBI Protein Information
RB-associated KRAB zinc finger protein; zinc finger protein 769; RB-associated KRAB repressor
UniProt Protein Name
RB-associated KRAB zinc finger protein
UniProt Synonym Protein Names
RB-associated KRAB repressor; hRBaK; Zinc finger protein 769
UniProt Synonym Gene Names
UniProt Entry Name
RBAK_HUMAN
NCBI Summary for RBAK
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus. [provided by RefSeq, Mar 2011]
UniProt Comments for RBAK
RBAK: May repress E2F-dependent transcription. May promote AR- dependent transcription. Belongs to the krueppel C2H2-type zinc-finger protein family.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 7p22.1
Cellular Component: nucleus
Molecular Function: nucleic acid binding; zinc ion binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; negative regulation of transcription, DNA-dependent
Research Articles on RBAK
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Products associated with RBAK elisa kit
Diseases associated with RBAK elisa kit
Organs/Tissues associated with RBAK elisa kit
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