NP_001247421.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
71,049 Da
NCBI Official Full Name
radixin isoform 1
NCBI Official Synonym Full Names
radixin
NCBI Official Synonym Symbols
NCBI Protein Information
radixin
UniProt Protein Name
Radixin
UniProt Entry Name
RADI_HUMAN
NCBI Summary for RDX
Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
UniProt Comments for RDX
Radixin: a cytoskeletal protein of the ERM family which includes ezrin and moiesin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. May play a crucial role in the binding of the barbed end of actin filaments to the plasma membrane.
Protein type: Motility/polarity/chemotaxis; Cytoskeletal
Chromosomal Location of Human Ortholog: 11q23
Cellular Component: extracellular space; focal adhesion; T-tubule; ruffle; stereocilium; cytoskeleton; extrinsic to membrane; apical part of cell; lamellipodium; cytoplasm; plasma membrane; cleavage furrow; filopodium
Molecular Function: protein binding; actin binding
Biological Process: microvillus biogenesis; apical protein localization; actin filament capping
Disease: Deafness, Autosomal Recessive 24
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Products associated with RDX elisa kit
Pathways associated with RDX elisa kit
Diseases associated with RDX elisa kit
Organs/Tissues associated with RDX elisa kit
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