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RASGRF2 elisa kit :: Human Ras protein-specific guanine nucleotide-releasing factor 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9333238 RASGRF2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ras protein-specific guanine nucleotide-releasing factor 2 (RASGRF2), ELISA Kit

★Popular Item★
 Also Known As   

Human Ras-specific guanine nucleotide-releasing factor 2, RASGRF2 ELISA Kit

 Product Synonym Names    Human Ras-specific guanine nucleotide-releasing factor 2 (RASGRF2) ELISA kit; DKFZp781H1715; GRF2; RAS-GRF2; ; Ras protein-specific guanine nucleotide-releasing factor 2
 Product Gene Name   

RASGRF2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    606614
 3D Structure    ModBase 3D Structure for O14827
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    0.25 ng/ml - 8 ng/ml
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RASGRF2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RASGRF2 purchase    MBS9333238 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ras protein-specific guanine nucleotide-releasing factor 2 (RASGRF2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 ng/ml - 8 ng/ml in biological research samples containing RASGRF2, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9333238 kit is based on RASGRF2 antibody-RASGRF2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RASGRF2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RASGRF2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for RASGRF2 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of RASGRF2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9333238. Click to request current manual
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NCBI/Uniprot data below describe general gene information for RASGRF2. It may not necessarily be applicable to this product.
 NCBI GI #    38505170
 NCBI GeneID    5924
 NCBI Accession #    NP_008840.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006909.2 [Other Products]
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 UniProt Primary Accession #    O14827 [Other Products]
 UniProt Secondary Accession #    Q9UK56; B9EG89 [Other Products]
 UniProt Related Accession #    O14827 [Other Products]
 Molecular Weight    140,764 Da
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 NCBI Official Full Name    ras-specific guanine nucleotide-releasing factor 2
 NCBI Official Synonym Full Names    Ras protein-specific guanine nucleotide-releasing factor 2
 NCBI Official Symbol    RASGRF2 [Similar Products]
 NCBI Official Synonym Symbols   
GRF2; RAS-GRF2
[Similar Products]
 NCBI Protein Information    ras-specific guanine nucleotide-releasing factor 2; ras guanine nucleotide exchange factor 2
 UniProt Protein Name    Ras-specific guanine nucleotide-releasing factor 2
 UniProt Synonym Protein Names   
Ras guanine nucleotide exchange factor 2
 Protein Family    Ras-specific guanine nucleotide-releasing factor
 UniProt Gene Name    RASGRF2 [Similar Products]
 UniProt Synonym Gene Names    GRF2; Ras-GRF2 [Similar Products]
 UniProt Entry Name    RGRF2_HUMAN
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 NCBI Summary for RASGRF2    RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011]
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 UniProt Comments for RASGRF2    RASGRF2: Functions as a calcium-regulated nucleotide exchange factor activating both Ras and RAC1 through the exchange of bound GDP for GTP. Preferentially activates HRAS in vivo compared to RRAS based on their different types of prenylation. Functions in synaptic plasticity by contributing to the induction of long term potentiation.

Protein type: GEFs; GEFs, Ras

Chromosomal Location of Human Ortholog: 5q13

Cellular Component: endoplasmic reticulum membrane; plasma membrane; cytosol

Molecular Function: calmodulin binding; Rho guanyl-nucleotide exchange factor activity

Biological Process: synaptic transmission; regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; small GTPase mediated signal transduction
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 Research Articles on RASGRF2    1. these results suggest that betaarrestin1 regulates rasgrf2 gene expression and Rac activation to affect membrane protrusion and cell migration and invasion.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RASGRF2 elisa kitDiseases associated with RASGRF2 elisa kit
 Products by Pathway  Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 CREB Phosphorylation Through The Activation Of Ras Pathway antibodies  CREB Phosphorylation Through The Activation Of Ras Pathway Diagram
 Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies  Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram
 G Alpha (12/13) Signalling Events Pathway antibodies  G Alpha (12/13) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 NRAGE Signals Death Through JNK Pathway antibodies  NRAGE Signals Death Through JNK Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >8 publications with RASGRF2 and Neoplasms
 Cell Transformation, Neoplastic Antibodies  >2 publications with RASGRF2 and Cell Transformation, Neoplastic
 Lung Neoplasms Antibodies  >1 publications with RASGRF2 and Lung Neoplasms
 Cardiovascular Diseases Antibodies  >1 publications with RASGRF2 and Cardiovascular Diseases
 Necrosis Antibodies  >1 publications with RASGRF2 and Necrosis
Organs/Tissues associated with RASGRF2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with RASGRF2 and Brain
 Lung Antibodies  >2 publications with RASGRF2 and Lung
 Embryonic Tissue Antibodies  >1 publications with RASGRF2 and Embryonic Tissue
 Muscle Antibodies  >1 publications with RASGRF2 and Muscle
 Prostate Antibodies  >1 publications with RASGRF2 and Prostate
 Spleen Antibodies  >1 publications with RASGRF2 and Spleen
 Kidney Antibodies  >1 publications with RASGRF2 and Kidney
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