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RRAGA elisa kit :: Human Ras-related GTP binding A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9334409 RRAGA elisa kit
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Ras-related GTP binding A (RRAGA), ELISA Kit

 Also Known As   

Human Ras-related GTP-binding protein A, RRAGA ELISA Kit

 Product Synonym Names    Human Ras-related GTP-binding protein A (RRAGA) ELISA kit; FIP-1; FIP1; RAGA; Ras-related GTP-binding protein; adenovirus E3-14.7K interacting protein 1; Ras-related GTP binding A
 Product Gene Name   

RRAGA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    612194
 3D Structure    ModBase 3D Structure for Q7L523
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 Species Reactivity    Human
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RRAGA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RRAGA purchase    MBS9334409 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Ras-related GTP binding A (RRAGA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RRAGA. The ELISA analytical biochemical technique of the MBS9334409 kit is based on RRAGA antibody-RRAGA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RRAGA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RRAGA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RRAGA. It may not necessarily be applicable to this product.
 NCBI GI #    5729999
 NCBI GeneID    10670
 NCBI Accession #    NP_006561.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006570.4 [Other Products]
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 UniProt Primary Accession #    Q7L523 [Other Products]
 UniProt Secondary Accession #    O00290; Q15347; B2R7L1 [Other Products]
 UniProt Related Accession #    Q7L523 [Other Products]
 Molecular Weight    36,566 Da
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 NCBI Official Full Name    ras-related GTP-binding protein A
 NCBI Official Synonym Full Names    Ras-related GTP binding A
 NCBI Official Symbol    RRAGA [Similar Products]
 NCBI Official Synonym Symbols   
FIP1; RAGA; FIP-1
[Similar Products]
 NCBI Protein Information    ras-related GTP-binding protein A; rag A; adenovirus E3-14.7K interacting protein 1; adenovirus E3 14.7 kDa-interacting protein 1
 UniProt Protein Name    Ras-related GTP-binding protein A
 UniProt Synonym Protein Names   
Adenovirus E3 14.7 kDa-interacting protein 1; FIP-1
 UniProt Gene Name    RRAGA [Similar Products]
 UniProt Synonym Gene Names    Rag A; RagA [Similar Products]
 UniProt Entry Name    RRAGA_HUMAN
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 UniProt Comments for RRAGA    RRAGA: Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity. Required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF- alpha signaling pathway leading to induction of cell death. May alternatively act as a cellular target for adenovirus E3-14.7K, an inhibitor of TNF-alpha functions, thereby affecting cell death. Can occur as a homodimer, or form a heterodimer with RRAGC or RRAGD in a sequence-independent manner. Binds GTP. The GTP-bound form of RRAGA interacts with NOL8. Interacts with adenovirus E3 14.7 kDa protein. Ubiquitously expressed with highest levels of expression in skeletal muscle, heart, and brain. Belongs to the GTR/RAG GTP-binding protein family.

Protein type: G protein regulator, misc.

Chromosomal Location of Human Ortholog: 9p22.1

Cellular Component: Golgi apparatus; intracellular membrane-bound organelle; lysosomal membrane; lysosome; cytoplasm; nucleus

Molecular Function: GTPase activity; protein binding; GDP binding; protein homodimerization activity; GTP binding; protein heterodimerization activity; phosphoprotein binding

Biological Process: cell death; apoptosis; metabolic process; virus-host interaction; regulation of autophagy; positive regulation of cytolysis; cellular response to starvation; positive regulation of TOR signaling pathway
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with RRAGA elisa kitPathways associated with RRAGA elisa kit
 Reference Product  PubMed Publications
 RRAGC elisa kit  >4 publications with RRAGA and RRAGC
 RRAGD elisa kit  >3 publications with RRAGA and RRAGD
 RHEB elisa kit  >2 publications with RRAGA and RHEB
 MTOR elisa kit  >1 publications with RRAGA and MTOR
 NIP7 elisa kit  >1 publications with RRAGA and NIP7
 NOL8 elisa kit  >1 publications with RRAGA and NOL8
 Products by Pathway  Pathway Diagram
 TOR Signaling Pathway antibodies  TOR Signaling Pathway Diagram
 MTOR Signaling Pathway antibodies  MTOR Signaling Pathway Diagram
 MTOR Signaling Pathway antibodies  MTOR Signaling Pathway Diagram
Diseases associated with RRAGA elisa kitOrgans/Tissues associated with RRAGA elisa kit
 Disease Name  Pubmed Publications
 Hematologic Diseases Antibodies  >1 publications with RRAGA and Hematologic Diseases
 Neoplasms Antibodies  >1 publications with RRAGA and Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Adrenal Gland Antibodies  >1 publications with RRAGA and Adrenal Gland
 Thymus Antibodies  >1 publications with RRAGA and Thymus
 Kidney Antibodies  >1 publications with RRAGA and Kidney
 Brain Antibodies  >1 publications with RRAGA and Brain
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