AAH09017.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
10,180 Da
NCBI Official Full Name
S100A6 protein
NCBI Official Synonym Full Names
S100 calcium binding protein A6
NCBI Protein Information
protein S100-A6; MLN 4; calcyclin; growth factor-inducible protein 2A9; prolactin receptor-associated protein; S100 calcium-binding protein A6 (calcyclin)
UniProt Protein Name
Protein S100-A6
UniProt Synonym Protein Names
Calcyclin; Growth factor-inducible protein 2A9; MLN 4; Prolactin receptor-associated protein; PRA; S100 calcium-binding protein A6
UniProt Synonym Gene Names
UniProt Entry Name
S10A6_HUMAN
NCBI Summary for S100A6
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]
UniProt Comments for S100A6
S100A6: May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family.
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: ruffle; extrinsic to internal side of plasma membrane; perinuclear region of cytoplasm; cytoplasm; nuclear envelope; cytosol; nucleus
Molecular Function: protein binding; protein homodimerization activity; zinc ion binding; ion transmembrane transporter activity; calcium ion binding; tropomyosin binding; calcium-dependent protein binding
Biological Process: positive regulation of fibroblast proliferation; axonogenesis; signal transduction
Research Articles on S100A6
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Products associated with S100A6 elisa kit
Pathways associated with S100A6 elisa kit
Diseases associated with S100A6 elisa kit
Organs/Tissues associated with S100A6 elisa kit
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