CAG46961.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
11,471 Da
NCBI Official Full Name
S100A7
UniProt Protein Name
Protein S100-A7
UniProt Synonym Protein Names
Psoriasin; S100 calcium-binding protein A7
UniProt Synonym Gene Names
UniProt Entry Name
S10A7_HUMAN
UniProt Comments for S100A7
S100A7: is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]
Chromosomal Location of Human Ortholog: 1q21
Cellular Component: focal adhesion; endoplasmic reticulum; cytoplasm; extracellular region; nucleus; cytosol
Molecular Function: RAGE receptor binding; protein binding; zinc ion binding; calcium ion binding
Biological Process: keratinocyte differentiation; sequestering of metal ion; response to reactive oxygen species; epidermis development; innate immune response; response to lipopolysaccharide; angiogenesis; defense response to Gram-negative bacterium
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Products associated with S100A7 elisa kit
Diseases associated with S100A7 elisa kit
Organs/Tissues associated with S100A7 elisa kit
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