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SCCA2 elisa kit :: Human SCCA2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2502115
Typical Standard Curve/Testing Data
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SCCA2, ELISA Kit

★Popular Item★
 Also Known As   

Human SCCA2 (Squamous Cell Carcinoma Antigen 2) ELISA Kit

 Product Gene Name   

SCCA2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2502115 COA    COA PDF
 OMIM    600518
 3D Structure    ModBase 3D Structure for P48594
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and some recombinant Human SCCA2. No significant crossreactivity or interference between Human SCCA2 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids
 Assay Type    Quantitative Sandwich
 Detection Range    0.16-10 ng/mL
 Sensitivity    Human SCCA2 is 0.10 ng/mL
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 Preparation and Storage    Store at 4 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SCCA2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SCCA2 purchase    MBS2502115 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SCCA2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.16-10 ng/mL in biological research samples containing SCCA2, with an estimated sensitivity of Human SCCA2 is 0.10 ng/mL. The ELISA analytical biochemical technique of the MBS2502115 kit is based on SCCA2 antibody-SCCA2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SCCA2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SCCA2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for SCCA2 elisa kit

   Intended Uses: This ELISA kit can be applied to the in vitro quantitative determination of Human SCCA2 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been precoated with an antibody specific to Human SCCA2. Standards or samples are added to appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibodies specific for Human SCCA2 and Avidin-Horseradish Peroxidase (HRP) conjugate are added to each micro plate well successively and incubated. After incubation, free components are washed away. Then the Substrate Reagent is added to each well, only those wells that contain Human SCCA2, biotinylated detection antibody and Avidin- HRP conjugate will appear blue in color. The enzyme-substrate reaction will be terminated by adding Stop Solution and appears yellow in color. The optical density (OD) can be measured with spectrophotometry at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human SCCA2. The concentration of Human SCCA2 in samples can be calculated by comparing the OD of the samples with the standard curve.
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 Typical Standard Curve/Testing Data of SCCA2 elisa kit    SCCA2 elisa kit Typical Standard Curve/Testing Data image
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Sample Manual Insert of MBS2502115. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SCCA2. It may not necessarily be applicable to this product.
 NCBI GI #    28076869
 NCBI GeneID    6318
 NCBI Accession #    NP_002965.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002974.3 [Other Products]
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 UniProt Primary Accession #    P48594 [Other Products]
 UniProt Secondary Accession #    A8K847 [Other Products]
 UniProt Related Accession #    P48594 [Other Products]
 Molecular Weight    44,854 Da
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 NCBI Official Full Name    serpin B4 isoform 1
 NCBI Official Synonym Full Names    serpin peptidase inhibitor, clade B (ovalbumin), member 4
 NCBI Official Symbol    SERPINB4 [Similar Products]
 NCBI Official Synonym Symbols   
PI11; SCCA1; SCCA2; LEUPIN; SCCA-2
[Similar Products]
 NCBI Protein Information    serpin B4; SCCA2/SCCA1 fusion protein; peptidase inhibitor 11; protease inhibitor (leucine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 4; squamous cell carcinoma antigen 1; squamous cell carcinoma antigen 2
 UniProt Protein Name    Serpin B4
 UniProt Synonym Protein Names   
Leupin; Peptidase inhibitor 11; PI-11; Squamous cell carcinoma antigen 2; SCCA-2
 UniProt Gene Name    SERPINB4 [Similar Products]
 UniProt Synonym Gene Names    PI11; SCCA2; PI-11; SCCA-2 [Similar Products]
 UniProt Entry Name    SPB4_HUMAN
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 UniProt Comments for SCCA2    SERPINB4: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily.

Protein type: Inhibitor

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: extracellular space; cytoplasm; intracellular

Molecular Function: serine-type endopeptidase inhibitor activity; enzyme binding; protease binding

Biological Process: regulation of proteolysis; negative regulation of peptidase activity; protection from natural killer cell mediated cytotoxicity
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 Research Articles on SCCA2    1. we identified four proteins with different expression in paclitaxel resistant cells, i.e., serpin B3, serpin B4, heat shock protein 27 (all three upregulated) and cytokeratin 18 (downregulated).
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SCCA2 elisa kitPathways associated with SCCA2 elisa kit
 Reference Product  PubMed Publications
 SERPINB3 elisa kit  >12 publications with SCCA2 and SERPINB3
 CMA1 elisa kit  >1 publications with SCCA2 and CMA1
 CTSS elisa kit  >1 publications with SCCA2 and CTSS
 CTSG elisa kit  >1 publications with SCCA2 and CTSG
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
Diseases associated with SCCA2 elisa kitOrgans/Tissues associated with SCCA2 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >9 publications with SCCA2 and Carcinoma
 Carcinoma, Squamous Cell Antibodies  >8 publications with SCCA2 and Carcinoma, Squamous Cell
 Inflammation Antibodies  >3 publications with SCCA2 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >2 publications with SCCA2 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >1 publications with SCCA2 and Liver Diseases
 Adenocarcinoma Antibodies  >1 publications with SCCA2 and Adenocarcinoma
 Skin Neoplasms Antibodies  >1 publications with SCCA2 and Skin Neoplasms
 Liver Cirrhosis Antibodies  >1 publications with SCCA2 and Liver Cirrhosis
 Urinary Bladder Diseases Antibodies  >1 publications with SCCA2 and Urinary Bladder Diseases
 Liver Neoplasms Antibodies  >1 publications with SCCA2 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >6 publications with SCCA2 and Skin
 Larynx Antibodies  >1 publications with SCCA2 and Larynx
 Mouth Antibodies  >1 publications with SCCA2 and Mouth
 Lung Antibodies  >1 publications with SCCA2 and Lung
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