NP_055637.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
113,010 Da
NCBI Official Full Name
protein transport protein Sec24D
NCBI Official Synonym Full Names
SEC24 family member D
NCBI Protein Information
protein transport protein Sec24D; SEC24 family, member D; SEC24-related protein D; SEC24 related gene family, member D
UniProt Protein Name
Protein transport protein Sec24D
UniProt Synonym Protein Names
SEC24-related protein D
UniProt Synonym Gene Names
UniProt Entry Name
SC24D_HUMAN
NCBI Summary for SEC24D
The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. This gene product is implicated in the shaping of the vesicle, and also in cargo selection and concentration. [provided by RefSeq, Jul 2008]
UniProt Comments for SEC24D
SEC24D: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with TMED2 and TMED10. Ubiquitously expressed, with higher amounts in placenta, pancreas, heart and liver. Belongs to the SEC23/SEC24 family. SEC24 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 4q26
Cellular Component: Golgi membrane; endoplasmic reticulum membrane; COPII vesicle coat; perinuclear region of cytoplasm; cytosol
Molecular Function: zinc ion binding
Biological Process: COPII coating of Golgi vesicle; intracellular protein transport; antigen processing and presentation of peptide antigen via MHC class I; ER to Golgi vesicle-mediated transport; cellular protein metabolic process; in utero embryonic development; antigen processing and presentation of exogenous peptide antigen via MHC class II; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
Disease: Cole-carpenter Syndrome 2
Research Articles on SEC24D
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Products associated with SEC24D elisa kit
Pathways associated with SEC24D elisa kit
Diseases associated with SEC24D elisa kit
Organs/Tissues associated with SEC24D elisa kit
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