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SEMA4C elisa kit :: Human SEMA4C ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2504258
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Human SEMA4C (Semaphorin 4C) ELISA Kit

 Product Gene Name   

SEMA4C elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    604462
 3D Structure    ModBase 3D Structure for Q9C0C4
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinant Human SEMA4C. No significant cross-reactivity or interference between Human SEMA4C and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SEMA4C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SEMA4C purchase    MBS2504258 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SEMA4C, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing SEMA4C, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2504258 kit is based on SEMA4C antibody-SEMA4C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SEMA4C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SEMA4C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SEMA4C elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human SEMA4C concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to SEMA4C. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for SEMA4C and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain SEMA4C, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of SEMA4C. You can calculate the concentration of SEMA4C in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of SEMA4C elisa kit    SEMA4C elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2504258. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SEMA4C. It may not necessarily be applicable to this product.
 NCBI GI #    157388902
 NCBI GeneID    54910
 NCBI Accession #    NP_060259.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_017789.4 [Other Products]
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 UniProt Primary Accession #    Q9C0C4 [Other Products]
 UniProt Secondary Accession #    Q32MJ3; Q7Z5X0 [Other Products]
 UniProt Related Accession #    Q9C0C4 [Other Products]
 Molecular Weight    92,623 Da
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 NCBI Official Full Name    semaphorin-4C
 NCBI Official Synonym Full Names    sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
 NCBI Official Symbol    SEMA4C [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    semaphorin-4C; M-Sema F
 UniProt Protein Name    Semaphorin-4C
 Protein Family    Semaphorin
 UniProt Gene Name    SEMA4C [Similar Products]
 UniProt Synonym Gene Names    KIAA1739; SEMAI [Similar Products]
 UniProt Entry Name    SEM4C_HUMAN
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 UniProt Comments for SEMA4C    SEMA4C: Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration. Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade. Belongs to the semaphorin family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: extracellular space; postsynaptic membrane; synaptic vesicle membrane; postsynaptic density; integral to membrane; cell junction

Molecular Function: receptor activity

Biological Process: cell migration in hindbrain; muscle cell differentiation; neural tube closure; cerebellum development; positive regulation of stress-activated MAPK cascade
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 Research Articles on SEMA4C    1. Data suggest that Erbin can interact with Sema4C, and co-expression of Erbin blocks the process of Sema4C-induced epithelial-mesenchymal transition.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SEMA4C elisa kitPathways associated with SEMA4C elisa kit
 Reference Product  PubMed Publications
 PLXNB1 elisa kit  >3 publications with SEMA4C and PLXNB1
 GIPC1 elisa kit  >2 publications with SEMA4C and GIPC1
 MERTK elisa kit  >1 publications with SEMA4C and MERTK
 CNGA3 elisa kit  >1 publications with SEMA4C and CNGA3
 PLXNB2 elisa kit  >1 publications with SEMA4C and PLXNB2
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
Diseases associated with SEMA4C elisa kitOrgans/Tissues associated with SEMA4C elisa kit
 Disease Name  Pubmed Publications
 Fibrosis Antibodies  >2 publications with SEMA4C and Fibrosis
 Neural Tube Defects Antibodies  >1 publications with SEMA4C and Neural Tube Defects
 Fatty Liver Antibodies  >1 publications with SEMA4C and Fatty Liver
 Brain Diseases Antibodies  >1 publications with SEMA4C and Brain Diseases
 Kidney Diseases Antibodies  >1 publications with SEMA4C and Kidney Diseases
 Disease Models, Animal Antibodies  >1 publications with SEMA4C and Disease Models, Animal
 Inflammation Antibodies  >1 publications with SEMA4C and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >10 publications with SEMA4C and Nerve
 Brain Antibodies  >7 publications with SEMA4C and Brain
 Kidney Antibodies  >4 publications with SEMA4C and Kidney
 Embryonic Tissue Antibodies  >4 publications with SEMA4C and Embryonic Tissue
 Lung Antibodies  >2 publications with SEMA4C and Lung
 Muscle Antibodies  >2 publications with SEMA4C and Muscle
 Skin Antibodies  >2 publications with SEMA4C and Skin
 Liver Antibodies  >1 publications with SEMA4C and Liver
 Blood Antibodies  >1 publications with SEMA4C and Blood
 Stomach Antibodies  >1 publications with SEMA4C and Stomach
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