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SGK2 elisa kit :: Human SGK2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2515302
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   


★Popular Item★
 Also Known As   

Human SGK2 (Serum/Glucocorticoid Regulated Kinase 2) ELISA Kit

 Product Gene Name   

SGK2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    607589
 3D Structure    ModBase 3D Structure for Q9HBY8
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinant Human SGK2. No significant cross-reactivity or interference between Human SGK2 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    Min: 0.094ng/mL; Max: 10ng/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SGK2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SGK2 purchase    MBS2515302 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SGK2, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing SGK2, with an estimated sensitivity of Min: 0.094ng/mL; Max: 10ng/mL. The ELISA analytical biochemical technique of the MBS2515302 kit is based on SGK2 antibody-SGK2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SGK2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SGK2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SGK2 elisa kit

   Intended Uses: This ELISA kit applies to the in vitro quantitative determination of Human SGK2 concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to SGK2. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for SGK2 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain SGK2, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of SGK2. You can calculate the concentration of SGK2 in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of SGK2 elisa kit    SGK2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2515302. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SGK2. It may not necessarily be applicable to this product.
 NCBI GI #    312922369
 NCBI GeneID    10110
 NCBI Accession #    NP_001186193.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001199264.1 [Other Products]
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 UniProt Primary Accession #    Q9HBY8 [Other Products]
 UniProt Secondary Accession #    Q52PK5; Q5H8Y6; Q5H8Z1; Q5TZR3; Q9UKG6 [Other Products]
 UniProt Related Accession #    Q9HBY8 [Other Products]
 Molecular Weight    43,977 Da
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 NCBI Official Full Name    serine/threonine-protein kinase Sgk2 isoform alpha
 NCBI Official Synonym Full Names    serum/glucocorticoid regulated kinase 2
 NCBI Official Symbol    SGK2 [Similar Products]
 NCBI Official Synonym Symbols   
H-SGK2; dJ138B7.2
[Similar Products]
 NCBI Protein Information    serine/threonine-protein kinase Sgk2
 UniProt Protein Name    Serine/threonine-protein kinase Sgk2
 UniProt Synonym Protein Names   
Serum/glucocorticoid-regulated kinase 2
 Protein Family    Serine/threonine-protein kinase
 UniProt Gene Name    SGK2 [Similar Products]
 UniProt Entry Name    SGK2_HUMAN
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 NCBI Summary for SGK2    This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
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 UniProt Comments for SGK2    SGK2: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Highly expressed in liver, kidney and pancreas, and at lower levels in brain. Two specific sites, one in the kinase domain (Thr-253) and the other in the C-terminal regulatory region (Ser- 416), need to be phsphorylated for its full activation. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Kinase, protein; Protein kinase, AGC; EC; Protein kinase, Ser/Thr (non-receptor); AGC group; SGK family

Chromosomal Location of Human Ortholog: 20q13.2

Cellular Component: cytosol; nucleus

Molecular Function: protein serine/threonine kinase activity; potassium channel regulator activity; sodium channel regulator activity; ATP binding

Biological Process: positive regulation of transporter activity; regulation of cell growth; response to oxidative stress; protein amino acid phosphorylation; transmembrane transport; regulation of cell proliferation
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 Research Articles on SGK2    1. Activation of hepatocyte pregnane X receptor is mediated through serum- and glucocorticoid-regulated kinase (SGK)2.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SGK2 elisa kitPathways associated with SGK2 elisa kit
 Reference Product  PubMed Publications
 PDPK1 elisa kit  >5 publications with SGK2 and PDPK1
 PI3 elisa kit  >4 publications with SGK2 and PI3
 Products by Pathway  Pathway Diagram
 FoxO Signaling Pathway antibodies  FoxO Signaling Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Stimuli-sensing Channels Pathway antibodies  Stimuli-sensing Channels Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
Diseases associated with SGK2 elisa kitOrgans/Tissues associated with SGK2 elisa kit
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >3 publications with SGK2 and Kidney Diseases
 Hypertension Antibodies  >1 publications with SGK2 and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >13 publications with SGK2 and Kidney
 Blood Antibodies  >8 publications with SGK2 and Blood
 Brain Antibodies  >6 publications with SGK2 and Brain
 Intestine Antibodies  >4 publications with SGK2 and Intestine
 Liver Antibodies  >3 publications with SGK2 and Liver
 Lung Antibodies  >1 publications with SGK2 and Lung
 Muscle Antibodies  >1 publications with SGK2 and Muscle
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