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SGPP1 elisa kit :: Human SGPP1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2515773
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SGPP1, ELISA Kit

★Popular Item★
 Also Known As   

Human SGPP1 (Sphingosine-1-Phosphate Phosphatase 1) ELISA Kit

 Product Gene Name   

SGPP1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    612826
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 Species Reactivity    Human
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 Specificity    This kit recognizes natural and recombinantHumanSGPP1. No significant cross-reactivity or interference between HumanSGPP1 and analogues was observed.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    62.5-4000pg/mL
 Sensitivity    Min: 37.5pg/mL; Max: 4000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SGPP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SGPP1 purchase    MBS2515773 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SGPP1, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5-4000pg/mL in biological research samples containing SGPP1, with an estimated sensitivity of Min: 37.5pg/mL; Max: 4000pg/mL. The ELISA analytical biochemical technique of the MBS2515773 kit is based on SGPP1 antibody-SGPP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SGPP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SGPP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SGPP1 elisa kit

   Intended Uses: This ELISA kit applies to the invitro quantitative determination of HumanSGPP1concentrations in serum, plasma and other biological fluids.

Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to SGPP1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for SGPP1and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain SGPP1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of SGPP1.You can calculate the concentration of SGPP1in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of SGPP1 elisa kit    SGPP1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2515773. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SGPP1. It may not necessarily be applicable to this product.
 NCBI GI #    13540569
 NCBI GeneID    81537
 NCBI Accession #    NP_110418.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030791.2 [Other Products]
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 UniProt Secondary Accession #    Q9H189; B2RAH0 [Other Products]
 UniProt Related Accession #    Q9BX95 [Other Products]
 Molecular Weight    49,108 Da
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 NCBI Official Full Name    sphingosine-1-phosphate phosphatase 1
 NCBI Official Synonym Full Names    sphingosine-1-phosphate phosphatase 1
 NCBI Official Symbol    SGPP1 [Similar Products]
 NCBI Official Synonym Symbols   
SPPase1
[Similar Products]
 NCBI Protein Information    sphingosine-1-phosphate phosphatase 1; hSPP1; hSPPase1; sphingosine-1-phosphatase 1; spp1
 UniProt Protein Name    Sphingosine-1-phosphate phosphatase 1
 UniProt Synonym Protein Names   
Sphingosine-1-phosphatase 1
 Protein Family    Sphingosine-1-phosphate phosphatase
 UniProt Gene Name    SGPP1 [Similar Products]
 UniProt Synonym Gene Names    SPPase1; Spp1; hSPP1; hSPPase1 [Similar Products]
 UniProt Entry Name    SGPP1_HUMAN
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 NCBI Summary for SGPP1    Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009]
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 UniProt Comments for SGPP1    SGPP1: Has enzymatic activity against both sphingosine 1- phosphate (S1P) and dihydro-S1P. Regulates intracellular and extracellular S1P levels. Belongs to the type 2 lipid phosphate phosphatase family.

Protein type: Mitochondrial; Apoptosis; Motility/polarity/chemotaxis; Lipid Metabolism - sphingolipid; Endoplasmic reticulum; Membrane protein, integral; Phosphatase (non-protein); Membrane protein, multi-pass; Cytoskeletal; EC 3.1.3.-

Chromosomal Location of Human Ortholog: 14q23.2

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: sphingosine-1-phosphate phosphatase activity

Biological Process: sphinganine-1-phosphate metabolic process; sphingolipid metabolic process; sphingolipid biosynthetic process; dephosphorylation; sphingosine metabolic process
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 Research Articles on SGPP1    1. The sphingolipid phosphatase SGPP1, an antagonist of sphingosine-1-phosphate signaling, is a target of miR-95 that promotes radiation resistance.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SGPP1 elisa kitPathways associated with SGPP1 elisa kit
 Reference Product  PubMed Publications
 SPHK1 elisa kit  >6 publications with SGPP1 and SPHK1
 SGPL1 elisa kit  >3 publications with SGPP1 and SGPL1
 SPHK2 elisa kit  >3 publications with SGPP1 and SPHK2
 UGCG elisa kit  >1 publications with SGPP1 and UGCG
 ASAH1 elisa kit  >1 publications with SGPP1 and ASAH1
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Sphingolipid De Novo Biosynthesis Pathway antibodies  Sphingolipid De Novo Biosynthesis Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingolipid Metabolism Pathway antibodies  Sphingolipid Metabolism Pathway Diagram
 Sphingosine 1-phosphate (S1P) Pathway antibodies  Sphingosine 1-phosphate (S1P) Pathway Diagram
 Sphingosine And Sphingosine-1-phosphate Metabolism Pathway antibodies  Sphingosine And Sphingosine-1-phosphate Metabolism Pathway Diagram
Diseases associated with SGPP1 elisa kitOrgans/Tissues associated with SGPP1 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >3 publications with SGPP1 and Necrosis
 Cardiovascular Diseases Antibodies  >2 publications with SGPP1 and Cardiovascular Diseases
 Diabetes Mellitus, Type 2 Antibodies  >2 publications with SGPP1 and Diabetes Mellitus, Type 2
 Adenocarcinoma Antibodies  >1 publications with SGPP1 and Adenocarcinoma
 Breast Neoplasms Antibodies  >1 publications with SGPP1 and Breast Neoplasms
 Pancreatic Neoplasms Antibodies  >1 publications with SGPP1 and Pancreatic Neoplasms
 Abnormalities, Multiple Antibodies  >1 publications with SGPP1 and Abnormalities, Multiple
 Anemia Antibodies  >1 publications with SGPP1 and Anemia
 Fibrosis Antibodies  >1 publications with SGPP1 and Fibrosis
 Disease Models, Animal Antibodies  >1 publications with SGPP1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with SGPP1 and Blood
 Vascular Antibodies  >3 publications with SGPP1 and Vascular
 Placenta Antibodies  >3 publications with SGPP1 and Placenta
 Kidney Antibodies  >2 publications with SGPP1 and Kidney
 Liver Antibodies  >2 publications with SGPP1 and Liver
 Skin Antibodies  >1 publications with SGPP1 and Skin
 Prostate Antibodies  >1 publications with SGPP1 and Prostate
 Pancreas Antibodies  >1 publications with SGPP1 and Pancreas
 Bone Marrow Antibodies  >1 publications with SGPP1 and Bone Marrow
 Muscle Antibodies  >1 publications with SGPP1 and Muscle
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