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SLC elisa kit :: Human SLC ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2501747
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SLC, ELISA Kit

★Popular Item★
 Also Known As   

Human SLC (Secondary Lymphoid Tissue Chemokine) ELISA Kit

 Product Gene Name   

SLC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    602737
 3D Structure    ModBase 3D Structure for O00585
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Human SLC. No significant cross-reactivity or interference between Human SLC and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Human SLC and all the analogues, therefore, cross reaction may still exist.
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 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    78.125-5000pg/mL
 Sensitivity    Min: 46.875pg/mL; Max: 5000pg/mL
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 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SLC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLC purchase    MBS2501747 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SLC, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78.125-5000pg/mL in biological research samples containing SLC, with an estimated sensitivity of Min: 46.875pg/mL; Max: 5000pg/mL. The ELISA analytical biochemical technique of the MBS2501747 kit is based on SLC antibody-SLC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SLC elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of SLC in human serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human SLC. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Human SLC and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human SLC, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Human SLC. You can calculate the concentration of Human SLC in the samples by comparing the OD of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of SLC elisa kit    SLC elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2501747. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SLC. It may not necessarily be applicable to this product.
 NCBI GI #    4128129
 NCBI GeneID    6366
 NCBI Accession #    CAA06653.1 [Other Products]
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 UniProt Primary Accession #    O00585 [Other Products]
 UniProt Related Accession #    O00585 [Other Products]
 Molecular Weight    14,646 Da
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 NCBI Official Full Name    secondary lymphoid tissue chemokine
 NCBI Official Synonym Full Names    chemokine (C-C motif) ligand 21
 NCBI Official Symbol    CCL21 [Similar Products]
 NCBI Official Synonym Symbols   
ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21
[Similar Products]
 NCBI Protein Information    C-C motif chemokine 21; Efficient Chemoattractant for Lymphocytes; beta chemokine exodus-2; secondary lymphoid tissue chemokine; small inducible cytokine subfamily A (Cys-Cys), member 21
 UniProt Protein Name    C-C motif chemokine 21
 UniProt Synonym Protein Names   
6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21
 Protein Family    SLC2A4 regulator
 UniProt Gene Name    CCL21 [Similar Products]
 UniProt Synonym Gene Names    SCYA21; SLC [Similar Products]
 UniProt Entry Name    CCL21_HUMAN
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 NCBI Summary for SLC    This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
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 UniProt Comments for SLC    CCL21: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted; Chemokine

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine receptor binding; chemokine activity; CCR7 chemokine receptor binding

Biological Process: positive regulation of filopodium formation; positive regulation of I-kappaB kinase/NF-kappaB cascade; formation of immunological synapse; positive regulation of chemotaxis; positive regulation of dendritic cell antigen processing and presentation; cell maturation; positive regulation of cell adhesion mediated by integrin; positive regulation of JNK cascade; positive regulation of phosphoinositide 3-kinase activity; positive regulation of receptor-mediated endocytosis; G-protein coupled receptor protein signaling pathway; positive regulation of protein kinase B signaling cascade; positive regulation of pseudopodium formation; cell-cell signaling; positive regulation of actin filament polymerization; release of sequestered calcium ion into cytosol; positive regulation of protein kinase activity; T cell costimulation; ruffle organization and biogenesis; dendritic cell chemotaxis; establishment of T cell polarity; immune response; positive regulation of cell-matrix adhesion; inflammatory response
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 Research Articles on SLC    1. CCL21 was shown to be involved in the induction of ulcerative colitis. Suppression of CCL21 expression decreased damage induced from ulcerative colitis, indicating that CCL21 targeted therapy might be an effective treatment for this disease
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SLC elisa kitPathways associated with SLC elisa kit
 Reference Product  PubMed Publications
 CCR7 elisa kit  >473 publications with SLC and CCR7
 CXCL13 elisa kit  >122 publications with SLC and CXCL13
 CXCL10 elisa kit  >61 publications with SLC and CXCL10
 CCR6 elisa kit  >41 publications with SLC and CCR6
 CXCL9 elisa kit  >36 publications with SLC and CXCL9
 CXCR5 elisa kit  >28 publications with SLC and CXCR5
 CCR5 elisa kit  >26 publications with SLC and CCR5
 CXCL11 elisa kit  >15 publications with SLC and CXCL11
 CCL27 elisa kit  >14 publications with SLC and CCL27
 CCR1 elisa kit  >9 publications with SLC and CCR1
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
Diseases associated with SLC elisa kitOrgans/Tissues associated with SLC elisa kit
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >193 publications with SLC and Inflammation
 Autoimmune Diseases Antibodies  >94 publications with SLC and Autoimmune Diseases
 Disease Models, Animal Antibodies  >92 publications with SLC and Disease Models, Animal
 Necrosis Antibodies  >81 publications with SLC and Necrosis
 Nervous System Diseases Antibodies  >53 publications with SLC and Nervous System Diseases
 Arthritis, Rheumatoid Antibodies  >52 publications with SLC and Arthritis, Rheumatoid
 Lung Diseases Antibodies  >50 publications with SLC and Lung Diseases
 Vascular Diseases Antibodies  >47 publications with SLC and Vascular Diseases
 Cardiovascular Diseases Antibodies  >34 publications with SLC and Cardiovascular Diseases
 Intestinal Diseases Antibodies  >31 publications with SLC and Intestinal Diseases
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >389 publications with SLC and Lymph Node
 Vascular Antibodies  >143 publications with SLC and Vascular
 Spleen Antibodies  >101 publications with SLC and Spleen
 Lung Antibodies  >85 publications with SLC and Lung
 Liver Antibodies  >49 publications with SLC and Liver
 Embryonic Tissue Antibodies  >31 publications with SLC and Embryonic Tissue
 Kidney Antibodies  >27 publications with SLC and Kidney
 Muscle Antibodies  >22 publications with SLC and Muscle
 Pancreas Antibodies  >22 publications with SLC and Pancreas
 Intestine Antibodies  >21 publications with SLC and Intestine
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