NP_001120689.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
52,493 Da
NCBI Official Full Name
mothers against decapentaplegic homolog 9 isoform a
NCBI Official Synonym Full Names
SMAD family member 9
NCBI Official Synonym Symbols
PPH2; MADH6; MADH9; SMAD8; SMAD8A; SMAD8B [Similar Products]
NCBI Protein Information
mothers against decapentaplegic homolog 9; MAD homolog 9; SMAD, mothers against DPP homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9
UniProt Protein Name
Mothers against decapentaplegic homolog 9
UniProt Synonym Protein Names
Madh6; SMAD family member 9; SMAD 9; Smad9
UniProt Synonym Gene Names
MADH6; MADH9; MAD homolog 9; Mothers against DPP homolog 9; SMAD 9; Smad9 [Similar Products]
UniProt Entry Name
SMAD9_HUMAN
NCBI Summary for SMAD9
The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
UniProt Comments for SMAD9
Smad8: transcription factor phosphorylated and activated by bone morphogenetic protein receptor kinases. Phosphorylated Smads dimerize with collaborating Smad4 and are translocated into the nucleus, where they regulate transcription of target genes. Participates in a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation and apoptosis. Two alternatively spliced products have been described.
Protein type: DNA-binding; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 13q12-q14
Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; intracellular; nucleus; cytosol
Molecular Function: protein binding; DNA binding; metal ion binding; transcription factor activity; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
Biological Process: BMP signaling pathway; Mullerian duct regression; transcription, DNA-dependent; ureteric bud development; transforming growth factor beta receptor signaling pathway; positive regulation of transcription, DNA-dependent; cartilage development; midbrain development; response to hypoxia; positive regulation of cell differentiation; protein amino acid phosphorylation; hindbrain development
Disease: Pulmonary Hypertension, Primary, 2
Research Articles on SMAD9
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Products associated with SMAD9 elisa kit
Pathways associated with SMAD9 elisa kit
Diseases associated with SMAD9 elisa kit
Organs/Tissues associated with SMAD9 elisa kit
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