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SMOC2 elisa kit :: Human SPARC related modular calcium binding 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS928218
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

SPARC related modular calcium binding 2 (SMOC2), ELISA Kit

 Also Known As   

Human SPARC-related modular calcium-binding protein 2, SMOC2 ELISA Kit

 Product Synonym Names    Human SPARC-related modular calcium-binding protein 2 (SMOC2) ELISA kit; RP11-270C4__A.1; MST117; MSTP117; MSTP140; SMAP2; bA270C4A.1; bA37D8.1; dJ421D16.1; secreted modular calcium-binding protein 2; smooth muscle associated protein 2; thyroglobulin type-1 repeat containi; SPARC related modular calcium binding 2
 Product Gene Name   

SMOC2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 MBS928218 Testing Data    Testing Data PDF
 OMIM    607223
 3D Structure    ModBase 3D Structure for Q9H3U7
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human SMOC2. No significant cross-reactivity or interference between human SMOC2 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell culture superantes.
 Assay Type    Sandwich
 Detection Range    0.156 ng/ml -10 ng/ml.
 Sensitivity    0.039 ng /ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of SMOC2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SMOC2 purchase    MBS928218 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SPARC related modular calcium binding 2 (SMOC2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml -10 ng/ml in biological research samples containing SMOC2, with an estimated sensitivity of 0.039 ng /ml. The ELISA analytical biochemical technique of the MBS928218 kit is based on SMOC2 antibody-SMOC2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SMOC2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SMOC2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell culture superantes. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for SMOC2 elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for SMOC2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any SMOC2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SMOC2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SMOC2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of SMOC2 elisa kit    SMOC2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS928218
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NCBI/Uniprot data below describe general gene information for SMOC2. It may not necessarily be applicable to this product.
 NCBI GI #    262050673
 NCBI GeneID    64094
 NCBI Accession #    NP_001159884.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001166412.1 [Other Products]
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 UniProt Primary Accession #    Q9H3U7 [Other Products]
 UniProt Secondary Accession #    Q4G169; Q5TAT7; Q5TAT8; Q86VV9; Q96SF3; Q9H1L3; Q9H1L4; Q9H3U0; Q9H4F7; Q9HCV2; B3KPS7 [Other Products]
 UniProt Related Accession #    Q9H3U7 [Other Products]
 Molecular Weight    49,674 Da
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 NCBI Official Full Name    SPARC-related modular calcium-binding protein 2 isoform 2
 NCBI Official Synonym Full Names    SPARC related modular calcium binding 2
 NCBI Official Symbol    SMOC2 [Similar Products]
 NCBI Official Synonym Symbols   
DTDP1; SMAP2; MST117; MSTP117; MSTP140; bA37D8.1; bA270C4A.1; dJ421D16.1
[Similar Products]
 NCBI Protein Information    SPARC-related modular calcium-binding protein 2; SMAP-2; SMOC-2; smooth muscle associated protein 2; smooth muscle-associated protein 2; secreted modular calcium-binding protein 2; thyroglobulin type-1 repeat containing protein
 UniProt Protein Name    SPARC-related modular calcium-binding protein 2
 UniProt Synonym Protein Names   
Secreted modular calcium-binding protein 2; SMOC-2; Smooth muscle-associated protein 2; SMAP-2
 Protein Family    SPARC-related modular calcium-binding protein
 UniProt Gene Name    SMOC2 [Similar Products]
 UniProt Synonym Gene Names    SMAP2; MSTP117; SMOC-2; SMAP-2 [Similar Products]
 UniProt Entry Name    SMOC2_HUMAN
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 NCBI Summary for SMOC2    This gene encodes a member of the SPARC family (secreted protein acidic and rich in cysteine/osteonectin/BM-40), which are highly expressed during embryogenesis and wound healing. The gene product is a matricellular protein which promotes matrix assembly and can stimulate endothelial cell proliferation and migration, as well as angiogenic activity. Associated with pulmonary function, this secretory gene product contains a Kazal domain, two thymoglobulin type-1 domains, and two EF-hand calcium-binding domains. The encoded protein may serve as a target for controlling angiogenesis in tumor growth and myocardial ischemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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 UniProt Comments for SMOC2    SMOC2: Promotes matrix assembly and cell adhesiveness. Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. Defects in SMOC2 are the cause of dentin dysplasia typ1 (DTDP1). A dental defect in which both primary and secondary dentitions are affected. The clinical crowns of both permanent and deciduous teeth are of normal shape, form and color in most cases, although they may be slightly opalescent and blue or brown. Teeth may be very mobile and exfoliate spontaneously because of inadequate root formation. On radiographs, the roots are short and may be more pointed than normal. Pulp chambers are usually absent except for a chevron-shaped remnant in the crown. Root canals are usually absent. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding; Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: basement membrane

Molecular Function: heparin binding; calcium ion binding

Biological Process: extracellular matrix organization and biogenesis; signal transduction

Disease: Dentin Dysplasia, Type I
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 Research Articles on SMOC2    1. SMOC2 SNP may play a role in autoimmune thyroid disease susceptibility as a dominant polymorphism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with SMOC2 elisa kitOrgans/Tissues associated with SMOC2 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with SMOC2 and Neoplasms
 Carcinoma Antibodies  >1 publications with SMOC2 and Carcinoma
 Congenital Abnormalities Antibodies  >1 publications with SMOC2 and Congenital Abnormalities
 Arthritis, Rheumatoid Antibodies  >1 publications with SMOC2 and Arthritis, Rheumatoid
 Lung Neoplasms Antibodies  >1 publications with SMOC2 and Lung Neoplasms
 Inflammation Antibodies  >1 publications with SMOC2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >2 publications with SMOC2 and Bone
 Ovary Antibodies  >1 publications with SMOC2 and Ovary
 Kidney Antibodies  >1 publications with SMOC2 and Kidney
 Lung Antibodies  >1 publications with SMOC2 and Lung
 Mammary Gland Antibodies  >1 publications with SMOC2 and Mammary Gland
 Heart Antibodies  >1 publications with SMOC2 and Heart
 Connective Tissue Antibodies  >1 publications with SMOC2 and Connective Tissue
 Eye Antibodies  >1 publications with SMOC2 and Eye
 Testis Antibodies  >1 publications with SMOC2 and Testis
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