AAA19454.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
87,197 Da
NCBI Official Full Name
Stat1
NCBI Official Synonym Full Names
signal transducer and activator of transcription 1
NCBI Protein Information
signal transducer and activator of transcription 1
UniProt Protein Name
Signal transducer and activator of transcription 1
UniProt Entry Name
STAT1_MOUSE
UniProt Comments for STAT1
STAT1: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of certain receptor tyrosine kinases, GPCRs, and receptors for various interleukins and interferons. Forms homo- or heterodimers that translocate into the nucleus where they regulate transcription. Two alternatively spliced isoforms have been described.
Protein type: Transcription factor; DNA-binding
Cellular Component: nucleoplasm; axon; nuclear chromatin; dendrite; cytoplasm; nucleolus; nucleus
Molecular Function: identical protein binding; protein binding; signal transducer activity; protein homodimerization activity; enzyme binding; DNA binding; protein phosphatase 2A binding; sequence-specific DNA binding; double-stranded DNA binding; tumor necrosis factor receptor binding; transcription factor activity; CCR5 chemokine receptor binding
Biological Process: transcription from RNA polymerase II promoter; response to peptide hormone stimulus; response to cAMP; blood circulation; positive regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; response to lipopolysaccharide; signal transduction; response to exogenous dsRNA; tumor necrosis factor-mediated signaling pathway; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; negative regulation of viral protein levels in host cell; lipopolysaccharide-mediated signaling pathway; response to nutrient; caspase activation; response to drug; transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB cascade; JAK-STAT cascade; negative regulation of angiogenesis; response to bacterium; cellular response to insulin stimulus; response to mechanical stimulus; response to cytokine stimulus; negative regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter
Research Articles on STAT1
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Pathways associated with STAT1 elisa kit
Organs/Tissues associated with STAT1 elisa kit
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