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SERPINB3 elisa kit :: Human Serpin B3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2883420
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $380 +1 FREE 8GB USB
96-Strip-Wells  /  $500 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,840 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serpin B3 (SERPINB3), ELISA Kit

★Popular Item★
 Also Known As   

Human Serpin B3 ELISA Kit

 Product Synonym Names    Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; SERPINB3; SCCA; SCCA1
 Product Gene Name   

SERPINB3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2883420 Testing Data    Testing Data PDF
 OMIM    600517
 3D Structure    ModBase 3D Structure for P29508
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 Species Reactivity    Human
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 Specificity    Recombinant and natural Human Serpin B3
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 Assay Type    Sandwich
 Detection Range    78-5000 pg/mL
 Sensitivity    32pg/mL
 Intra-Assay CV    <=5.1%
 Inter-Assay CV    <=9.8%
 Recovery    107%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SERPINB3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SERPINB3 purchase    MBS2883420 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Serpin B3 (SERPINB3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78-5000 pg/mL in biological research samples containing SERPINB3, with an estimated sensitivity of 32pg/mL. The ELISA analytical biochemical technique of the MBS2883420 kit is based on SERPINB3 antibody-SERPINB3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SERPINB3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SERPINB3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SERPINB3 elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of SERPINB3 elisa kit    SERPINB3 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2883420. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SERPINB3. It may not necessarily be applicable to this product.
 NCBI GI #    5902072
 NCBI GeneID    6317
 NCBI Accession #    NP_008850.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006919.2 [Other Products]
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 UniProt Primary Accession #    P29508 [Other Products]
 UniProt Secondary Accession #    Q53H28; Q53YB5; Q86VF3; Q86W04; Q8IWL4; Q8IXI3; Q96J21; Q9BYF8; A6NDM2; B2RBT5; B3W5Y6 [Other Products]
 UniProt Related Accession #    P29508 [Other Products]
 Molecular Weight    38,550 Da
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 NCBI Official Full Name    serpin B3
 NCBI Official Synonym Full Names    serpin peptidase inhibitor, clade B (ovalbumin), member 3
 NCBI Official Symbol    SERPINB3 [Similar Products]
 NCBI Official Synonym Symbols   
SCC; T4-A; SCCA1; SCCA-1; HsT1196; SCCA-PD
[Similar Products]
 NCBI Protein Information    serpin B3
 UniProt Protein Name    Serpin B3
 UniProt Synonym Protein Names   
Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1
 Protein Family    Serpin
 UniProt Gene Name    SERPINB3 [Similar Products]
 UniProt Synonym Gene Names    SCCA; SCCA1; SCCA-1 [Similar Products]
 UniProt Entry Name    SPB3_HUMAN
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 UniProt Comments for SERPINB3    SERPINB3: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 18q21.3

Cellular Component: cytoplasm; cytoplasmic vesicle; extracellular space; nucleus; vesicle

Molecular Function: cysteine protease inhibitor activity; protease binding; serine-type endopeptidase inhibitor activity; viral receptor activity

Biological Process: entry of virus into host cell; negative regulation of catalytic activity; negative regulation of JNK activity; negative regulation of peptidase activity; negative regulation of proteolysis; positive regulation of cell migration; positive regulation of cell proliferation
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 Research Articles on SERPINB3    1. The diagnostic performance of SCCA-IgM immune complexes for hepatocellular carcinoma was found to be frequently superior to that of alpha-fetoprotein. (Review)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SERPINB3 elisa kitPathways associated with SERPINB3 elisa kit
 Reference Product  PubMed Publications
 CTSS elisa kit  >1 publications with SERPINB3 and CTSS
 CTSG elisa kit  >1 publications with SERPINB3 and CTSG
 MAPK8 elisa kit  >1 publications with SERPINB3 and MAPK8
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
Diseases associated with SERPINB3 elisa kitOrgans/Tissues associated with SERPINB3 elisa kit
 Disease Name  Pubmed Publications
 Carcinoma, Squamous Cell Antibodies  >36 publications with SERPINB3 and Carcinoma, Squamous Cell
 Liver Diseases Antibodies  >15 publications with SERPINB3 and Liver Diseases
 Inflammation Antibodies  >12 publications with SERPINB3 and Inflammation
 Neoplasms, Experimental Antibodies  >3 publications with SERPINB3 and Neoplasms, Experimental
 Mouth Neoplasms Antibodies  >3 publications with SERPINB3 and Mouth Neoplasms
 Hyperplasia Antibodies  >2 publications with SERPINB3 and Hyperplasia
 Cell Transformation, Neoplastic Antibodies  >2 publications with SERPINB3 and Cell Transformation, Neoplastic
 Ovarian Diseases Antibodies  >2 publications with SERPINB3 and Ovarian Diseases
 Lung Neoplasms Antibodies  >2 publications with SERPINB3 and Lung Neoplasms
 Fibrosis Antibodies  >2 publications with SERPINB3 and Fibrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >15 publications with SERPINB3 and Blood
 Mouth Antibodies  >3 publications with SERPINB3 and Mouth
 Lung Antibodies  >3 publications with SERPINB3 and Lung
 Cervix Antibodies  >2 publications with SERPINB3 and Cervix
 Brain Antibodies  >1 publications with SERPINB3 and Brain
 Larynx Antibodies  >1 publications with SERPINB3 and Larynx
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