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APCS elisa kit :: Human Serum amyloid P-component ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2881710
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $325 +1 FREE 8GB USB
96-Strip-Wells  /  $435 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,290 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Serum amyloid P-component (APCS), ELISA Kit

★Popular Item★
 Also Known As   

Human Serum amyloid P-component ELISA Kit

 Product Synonym Names    Serum amyloid P-component; SAP; 9.5S alpha-1-glycoprotein; APCS; PTX2
 Product Gene Name   

APCS elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2881710 Testing Data    Testing Data PDF
 OMIM    104770
 3D Structure    ModBase 3D Structure for P02743
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 Species Reactivity    Human
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 Specificity    Recombinant and natural Human Serum amyloid P-component,SAP
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 Samples    serum, plasma, tissue homogenates?cell culture supernates or other biological fluids
 Detection Range    6.25-400 ng/mL
 Sensitivity    <3 ng/mL
 Intra-assay Precision    Intra-Assay CV: ?4.7%
 Inter-assay Precision    Inter-Assay CV: ?8.6%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of APCS elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for APCS purchase    MBS2881710 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Serum amyloid P-component (APCS) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 6.25-400 ng/mL in biological research samples containing APCS, with an estimated sensitivity of <3 ng/mL. The ELISA analytical biochemical technique of the MBS2881710 kit is based on APCS antibody-APCS antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect APCS antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, APCS. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as serum, plasma, tissue homogenates?cell culture supernates or other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for APCS elisa kit

   Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates?cell culture supernates or other biological fluids.
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 Typical Testing Data/Standard Curve (for reference only) of APCS elisa kit    APCS elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2881710. Click to request current manual
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NCBI/Uniprot data below describe general gene information for APCS. It may not necessarily be applicable to this product.
 NCBI GI #    4502133
 NCBI GeneID    325
 NCBI Accession #    NP_001630.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001639.3 [Other Products]
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 UniProt Primary Accession #    P02743 [Other Products]
 UniProt Related Accession #    P02743 [Other Products]
 Molecular Weight    25,387 Da
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 NCBI Official Full Name    serum amyloid P-component
 NCBI Official Synonym Full Names    amyloid P component, serum
 NCBI Official Symbol    APCS [Similar Products]
 NCBI Official Synonym Symbols   
SAP; PTX2; HEL-S-92n
[Similar Products]
 NCBI Protein Information    serum amyloid P-component
 UniProt Protein Name    Serum amyloid P-component
 UniProt Synonym Protein Names   
9.5S alpha-1-glycoprotein
 Protein Family    Serum amyloid P-component
 UniProt Gene Name    APCS [Similar Products]
 UniProt Synonym Gene Names    PTX2; SAP [Similar Products]
 UniProt Entry Name    SAMP_HUMAN
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 NCBI Summary for APCS    The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]
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 UniProt Comments for APCS    APCS: Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. Belongs to the pentaxin family.

Protein type: Secreted; Chaperone; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 1q21-q23

Cellular Component: extracellular matrix; extracellular region; extracellular space; nucleus

Molecular Function: calcium ion binding; carbohydrate binding; complement component C1q binding; unfolded protein binding; virion binding

Biological Process: acute-phase response; cellular protein metabolic process; chaperone-mediated protein complex assembly; innate immune response; negative regulation of acute inflammatory response; negative regulation of monocyte differentiation; negative regulation of viral reproduction; negative regulation of virion penetration into host cell; protein folding
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 Research Articles on APCS    1. SNPs in APCS were associated with late age at onset in familial amyloid polyneuropathy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with APCS elisa kitPathways associated with APCS elisa kit
 Reference Product  PubMed Publications
 APP elisa kit  >3 publications with APCS and APP
 GSN elisa kit  >2 publications with APCS and GSN
 FCGR2A elisa kit  >2 publications with APCS and FCGR2A
 TTR elisa kit  >2 publications with APCS and TTR
 SAA1 elisa kit  >2 publications with APCS and SAA1
 FGA elisa kit  >1 publications with APCS and FGA
 Products by Pathway  Pathway Diagram
 Amyloid Fiber Formation Pathway antibodies  Amyloid Fiber Formation Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
Diseases associated with APCS elisa kitOrgans/Tissues associated with APCS elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1876 publications with APCS and Cardiovascular Diseases
 Heart Diseases Antibodies  >1832 publications with APCS and Heart Diseases
 Immune System Diseases Antibodies  >1027 publications with APCS and Immune System Diseases
 Inflammation Antibodies  >540 publications with APCS and Inflammation
 Necrosis Antibodies  >284 publications with APCS and Necrosis
 Congenital Abnormalities Antibodies  >187 publications with APCS and Congenital Abnormalities
 Myocardial Infarction Antibodies  >170 publications with APCS and Myocardial Infarction
 Heart Failure Antibodies  >164 publications with APCS and Heart Failure
 Hepatitis Antibodies  >93 publications with APCS and Hepatitis
 Liver Diseases Antibodies  >82 publications with APCS and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >539 publications with APCS and Bone
 Lung Antibodies  >250 publications with APCS and Lung
 Liver Antibodies  >178 publications with APCS and Liver
 Muscle Antibodies  >123 publications with APCS and Muscle
 Pancreas Antibodies  >70 publications with APCS and Pancreas
 Uncharacterized Tissue Antibodies  >2 publications with APCS and Uncharacterized Tissue
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