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SIGLEC7 elisa kit :: Human Sialic acid-binding Ig-like lectin 7 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2888006
 Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $420 +1 FREE 8GB USB
96-Strip-Wells  /  $560 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,445 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,520 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sialic acid-binding Ig-like lectin 7 (SIGLEC7), ELISA Kit

★Popular Item★
 Also Known As   

Human Sialic acid-binding Ig-like lectin 7 ELISA Kit

 Product Synonym Names    Sialic acid-binding Ig-like lectin 7; Siglec-7; Adhesion inhibitory receptor molecule 1; AIRM-1; CDw328; D-siglec; QA79 membrane protein; p75; SIGLEC7; AIRM1; CD328
 Product Gene Name   

SIGLEC7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS2888006 Testing Data    Testing Data PDF
 OMIM    604410
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 Species Reactivity    Human
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 Specificity    Recombinant and natural Human Sialic acid-binding Ig-like lectin 7,Siglec-7
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 Detection Range    0.156-10 ng/mL
 Intra-assay Precision    Intra-Assay CV: <=6.2%
 Inter-assay Precision    Inter-Assay CV: <=9.4%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SIGLEC7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SIGLEC7 purchase    MBS2888006 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sialic acid-binding Ig-like lectin 7 (SIGLEC7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10 ng/mL in biological research samples containing SIGLEC7. The ELISA analytical biochemical technique of the MBS2888006 kit is based on SIGLEC7 antibody-SIGLEC7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SIGLEC7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SIGLEC7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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  Typical Testing Data/Standard Curve (for reference only) of SIGLEC7 elisa kit    SIGLEC7 elisa kit  Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS2888006. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SIGLEC7. It may not necessarily be applicable to this product.
 NCBI GI #    7657570
 NCBI GeneID    27036
 NCBI Accession #    NP_055200.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_014385.3 [Other Products]
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 UniProt Secondary Accession #    Q9NZQ1; Q9UJ86; Q9UJ87; Q9Y502 [Other Products]
 UniProt Related Accession #    Q9Y286 [Other Products]
 Molecular Weight    16,740 Da
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 NCBI Official Full Name    sialic acid-binding Ig-like lectin 7 isoform 1
 NCBI Official Synonym Full Names    sialic acid binding Ig like lectin 7
 NCBI Official Symbol    SIGLEC7 [Similar Products]
 NCBI Official Synonym Symbols   
p75; QA79; AIRM1; CD328; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1
[Similar Products]
 NCBI Protein Information    sialic acid-binding Ig-like lectin 7
 UniProt Protein Name    Sialic acid-binding Ig-like lectin 7
 UniProt Synonym Protein Names   
Adhesion inhibitory receptor molecule 1; AIRM-1; CDw328; D-siglec; QA79 membrane protein; p75; CD_antigen: CD328
 Protein Family    Sialic acid-binding Ig-like lectin
 UniProt Gene Name    SIGLEC7 [Similar Products]
 UniProt Synonym Gene Names    AIRM1; Siglec-7; AIRM-1 [Similar Products]
 UniProt Entry Name    SIGL7_HUMAN
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 UniProt Comments for SIGLEC7    SIGLEC7: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro). Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: receptor activity

Biological Process: regulation of immune response
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 Research Articles on SIGLEC7    1. Siglec-7 plays a significant role in inhibiting IgE-mediated mast cell activation, but only moderately affects IgE-mediated activation in primary human basophils.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with SIGLEC7 elisa kitDiseases associated with SIGLEC7 elisa kit
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >6 publications with SIGLEC7 and Immune System Diseases
 Inflammation Antibodies  >4 publications with SIGLEC7 and Inflammation
 Kidney Diseases Antibodies  >4 publications with SIGLEC7 and Kidney Diseases
 Necrosis Antibodies  >2 publications with SIGLEC7 and Necrosis
 Colorectal Neoplasms Antibodies  >2 publications with SIGLEC7 and Colorectal Neoplasms
 Lung Neoplasms Antibodies  >2 publications with SIGLEC7 and Lung Neoplasms
 Nervous System Diseases Antibodies  >2 publications with SIGLEC7 and Nervous System Diseases
 Peripheral Nervous System Diseases Antibodies  >1 publications with SIGLEC7 and Peripheral Nervous System Diseases
 Cell Transformation, Neoplastic Antibodies  >1 publications with SIGLEC7 and Cell Transformation, Neoplastic
Organs/Tissues associated with SIGLEC7 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >32 publications with SIGLEC7 and Blood
 Liver Antibodies  >2 publications with SIGLEC7 and Liver
 Spleen Antibodies  >2 publications with SIGLEC7 and Spleen
 Eye Antibodies  >1 publications with SIGLEC7 and Eye
 Adrenal Gland Antibodies  >1 publications with SIGLEC7 and Adrenal Gland
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