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SLAMF7 elisa kit :: Human Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS453571
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $355 +1 FREE 8GB USB
96-Strip-Wells  /  $480 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,140 +2 FREE 8GB USB
10x96-Strip-Wells  /  $4,155 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7), ELISA Kit

★Popular Item★
 Also Known As   

Human Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) ELISA Kit

 Product Synonym Names    CD319; CRACC; 19A; CS1; CD2-like receptor-activating cytotoxic cells; Membrane protein FOAP-12
 Product Gene Name   

SLAMF7 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    AF291815 mRNA
 3D Structure    ModBase 3D Structure for Q9NQ25
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of SLAMF7. No significant cross-reactivity or interference between SLAMF7 and analogues was observed.
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 Samples    Tissue homogenates, cell lysates and other biological fluids.
 Assay Type    Sandwich
 Detection Range    0.156-10ng/mL
 Sensitivity    0.053ng/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level SLAMF7 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level SLAMF7 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
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 Preparation and Storage    For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SLAMF7 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SLAMF7 purchase    MBS453571 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/mL in biological research samples containing SLAMF7, with an estimated sensitivity of 0.053ng/mL. The ELISA analytical biochemical technique of the MBS453571 kit is based on SLAMF7 antibody-SLAMF7 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLAMF7 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLAMF7. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Tissue homogenates, cell lysates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SLAMF7 elisa kit

   Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of SLAMF7 in human tissue homogenates, cell lysates and other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to SLAMF7. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to SLAMF7. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain SLAMF7, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm +/- 10nm. The concentration of SLAMF7 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of SLAMF7 elisa kit    SLAMF7 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS453571. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SLAMF7. It may not necessarily be applicable to this product.
 NCBI GI #    543583691
 NCBI GeneID    57823
 NCBI Accession #    NP_001269517.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001282588.1 [Other Products]
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 UniProt Primary Accession #    Q9NQ25 [Other Products]
 UniProt Secondary Accession #    Q8N6Y8; Q8ND32; Q9NY08; Q9NY23; A8K3U1; B4DPU4; B4DPY3; B4DWA3 [Other Products]
 UniProt Related Accession #    Q9NQ25 [Other Products]
 Molecular Weight    21,316 Da
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 NCBI Official Full Name    SLAM family member 7 isoform b
 NCBI Official Synonym Full Names    SLAM family member 7
 NCBI Official Symbol    SLAMF7 [Similar Products]
 NCBI Official Synonym Symbols   
19A; CS1; CD319; CRACC
[Similar Products]
 NCBI Protein Information    SLAM family member 7
 UniProt Protein Name    SLAM family member 7
 UniProt Synonym Protein Names   
CD2 subset 1; CD2-like receptor-activating cytotoxic cells; CRACC; Membrane protein FOAP-12; Novel Ly9; Protein 19A; CD_antigen: CD319
 Protein Family    SLAM family
 UniProt Gene Name    SLAMF7 [Similar Products]
 UniProt Synonym Gene Names    CS1; CRACC [Similar Products]
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 UniProt Comments for SLAMF7    Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Isoform 1 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway (PubMed:11698418). Positively regulates NK cell functions by a mechanism dependent on phosphorylated SH2D1B. Downstream signaling implicates PLCG1, PLCG2 and PI3K (PubMed:16339536). In addition to heterotypic NK cells-target cells interactions also homotypic interactions between NK cells may contribute to activation. However, in the absence of SH2D1B, inhibits NK cell function. Acts also inhibitory in T-cells (). May play a role in lymphocyte adhesion (PubMed:11802771). In LPS-activated monocytes negatively regulates production of proinflammatory cytokines (PubMed:23695528).
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 Research Articles on SLAMF7    1. Blimp-1 regulates the transcription of CS1 gene in NK and B cell lines from multiple myeloma and diffuse large B cell lymphoma patients.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SLAMF7 elisa kitPathways associated with SLAMF7 elisa kit
 Reference Product  PubMed Publications
 CD244 elisa kit  >11 publications with SLAMF7 and CD244
 SH2D1A elisa kit  >5 publications with SLAMF7 and SH2D1A
 CD48 elisa kit  >4 publications with SLAMF7 and CD48
 SH2D1B elisa kit  >3 publications with SLAMF7 and SH2D1B
 FCRL1 elisa kit  >2 publications with SLAMF7 and FCRL1
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Diseases associated with SLAMF7 elisa kitOrgans/Tissues associated with SLAMF7 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >30 publications with SLAMF7 and Cardiovascular Diseases
 Disease Models, Animal Antibodies  >4 publications with SLAMF7 and Disease Models, Animal
 Inflammation Antibodies  >4 publications with SLAMF7 and Inflammation
 Necrosis Antibodies  >4 publications with SLAMF7 and Necrosis
 Fibrosis Antibodies  >2 publications with SLAMF7 and Fibrosis
 Hypersensitivity Antibodies  >1 publications with SLAMF7 and Hypersensitivity
 Pneumonia Antibodies  >1 publications with SLAMF7 and Pneumonia
 Lung Diseases Antibodies  >1 publications with SLAMF7 and Lung Diseases
 Kidney Diseases Antibodies  >1 publications with SLAMF7 and Kidney Diseases
 Hyperplasia Antibodies  >1 publications with SLAMF7 and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >49 publications with SLAMF7 and Blood
 Bone Antibodies  >13 publications with SLAMF7 and Bone
 Brain Antibodies  >2 publications with SLAMF7 and Brain
 Muscle Antibodies  >1 publications with SLAMF7 and Muscle
 Skin Antibodies  >1 publications with SLAMF7 and Skin
 Liver Antibodies  >1 publications with SLAMF7 and Liver
 Pancreas Antibodies  >1 publications with SLAMF7 and Pancreas
 Pharynx Antibodies  >1 publications with SLAMF7 and Pharynx
 Kidney Antibodies  >1 publications with SLAMF7 and Kidney
 Intestine Antibodies  >1 publications with SLAMF7 and Intestine
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