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CD80 elisa kit :: Human T-lymphocyte activation antigen CD80 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS760940
Unit / Price
48-Strip-Wells  /  $280 +1 FREE 8GB USB
96-Strip-Wells  /  $375 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,615 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,015 +3 FREE 8GB USB
15x96-Strip-Wells  /  $4,285 +5 FREE 8GB USB
25x96-Strip-Wells  /  $6,715 +8 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

T-lymphocyte activation antigen CD80, ELISA Kit

 Also Known As   

Human T-lymphocyte activation antigen CD80 ELISA Kit

 Product Synonym Names    CD80/B7-1/T-lymphocyte activation antigen CD80
 Product Gene Name   

CD80 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    112203
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 Species Reactivity    Human
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 Samples    Serum, plasma and other biological fluids.
 Assay Type    Sandwich ELISA, Double Antibody
 Detection Range    78-5000pg/ml
 Sensitivity    46.9pg/ml
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 Preparation and Storage    Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CD80 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CD80 purchase    MBS760940 is a ready-to-use microwell, strip plate Sandwich, Double Antibody ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the T-lymphocyte activation antigen CD80, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78-5000pg/ml in biological research samples containing CD80, with an estimated sensitivity of 46.9pg/ml. The ELISA analytical biochemical technique of the MBS760940 kit is based on CD80 antibody-CD80 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CD80 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CD80. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CD80 elisa kit

   Principle of the Assay||This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti-Human CD80 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti-Human CD80 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and wash with wash buffer. HRPStreptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the Human CD80 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of Human CD80 can be calculated.
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 Typical Testing Data of CD80 elisa kit    CD80 elisa kit Typical Testing Data image
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 Typical Standard Curve of CD80 elisa kit    CD80 elisa kit Typical Standard Curve image
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Sample Manual Insert of MBS760940. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CD80. It may not necessarily be applicable to this product.
 NCBI GI #    4885123
 NCBI GeneID    941
 NCBI Accession #    NP_005182.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005191.3 [Other Products]
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 UniProt Secondary Accession #    Q5DTA9; Q5DTB0 [Other Products]
 UniProt Related Accession #    P33681 [Other Products]
 Molecular Weight    18,761 Da
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 NCBI Official Full Name    T-lymphocyte activation antigen CD80
 NCBI Official Synonym Full Names    CD80 molecule
 NCBI Official Symbol    CD80 [Similar Products]
 NCBI Official Synonym Symbols   
B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1
[Similar Products]
 NCBI Protein Information    T-lymphocyte activation antigen CD80
 UniProt Protein Name    T-lymphocyte activation antigen CD80
 UniProt Synonym Protein Names   
Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80
 Protein Family    T-lymphocyte activation antigen
 UniProt Gene Name    CD80 [Similar Products]
 UniProt Synonym Gene Names    CD28LG; CD28LG1; LAB7; B7 [Similar Products]
 UniProt Entry Name    CD80_HUMAN
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 NCBI Summary for CD80    The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
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 UniProt Comments for CD80    CD80: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.

Protein type: Immunoglobulin superfamily; Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q13.3-q21

Cellular Component: cell surface; external side of plasma membrane; integral to membrane; intracellular; plasma membrane

Molecular Function: coreceptor activity; protein binding; viral receptor activity

Biological Process: cell-cell signaling; entry of virus into host cell; epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; innate immune response; nerve growth factor receptor signaling pathway; phosphoinositide-mediated signaling; positive regulation of alpha-beta T cell proliferation; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of interleukin-2 biosynthetic process; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of signal transduction; positive regulation of T-helper 1 cell differentiation; positive regulation of transcription, DNA-dependent; T cell activation; T cell costimulation
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 Research Articles on CD80    1. In the present study, we investigated the prognostic significance of the expression of three genes in the PD-L1 pathway, including PD-L1, B7.1 and PD-1, in three independent bladder cancer datasets in the Gene Expression Omnibus database.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with CD80 elisa kitPathways associated with CD80 elisa kit
 Reference Product  PubMed Publications
 CD86 elisa kit  >4964 publications with CD80 and CD86
 CD40 elisa kit  >2224 publications with CD80 and CD40
 CD28 elisa kit  >1854 publications with CD80 and CD28
 CTLA4 elisa kit  >1058 publications with CD80 and CTLA4
 HLA-A elisa kit  >106 publications with CD80 and HLA-A
 HLA-DRB1 elisa kit  >15 publications with CD80 and HLA-DRB1
 IFNG elisa kit  >7 publications with CD80 and IFNG
 CD8A elisa kit  >4 publications with CD80 and CD8A
 CD247 elisa kit  >1 publications with CD80 and CD247
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Allograft Rejection Pathway antibodies  Allograft Rejection Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 Autoimmune Thyroid Disease Pathway antibodies  Autoimmune Thyroid Disease Pathway Diagram
 CD28 Co-stimulation Pathway antibodies  CD28 Co-stimulation Pathway Diagram
 CD28 Dependent PI3K/Akt Signaling Pathway antibodies  CD28 Dependent PI3K/Akt Signaling Pathway Diagram
 CD28 Dependent Vav1 Pathway antibodies  CD28 Dependent Vav1 Pathway Diagram
 CTLA4 Inhibitory Signaling Pathway antibodies  CTLA4 Inhibitory Signaling Pathway Diagram
Diseases associated with CD80 elisa kitOrgans/Tissues associated with CD80 elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >1163 publications with CD80 and Necrosis
 Inflammation Antibodies  >818 publications with CD80 and Inflammation
 Neoplasms, Experimental Antibodies  >367 publications with CD80 and Neoplasms, Experimental
 Lung Diseases Antibodies  >319 publications with CD80 and Lung Diseases
 Liver Diseases Antibodies  >236 publications with CD80 and Liver Diseases
 Cardiovascular Diseases Antibodies  >187 publications with CD80 and Cardiovascular Diseases
 Kidney Diseases Antibodies  >172 publications with CD80 and Kidney Diseases
 Lung Neoplasms Antibodies  >113 publications with CD80 and Lung Neoplasms
 Liver Neoplasms Antibodies  >110 publications with CD80 and Liver Neoplasms
 Breast Neoplasms Antibodies  >85 publications with CD80 and Breast Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >6155 publications with CD80 and Blood
 Lymph Node Antibodies  >604 publications with CD80 and Lymph Node
 Lung Antibodies  >432 publications with CD80 and Lung
 Thymus Antibodies  >190 publications with CD80 and Thymus
 Tonsil Antibodies  >40 publications with CD80 and Tonsil
 Connective Tissue Antibodies  >36 publications with CD80 and Connective Tissue
 Mammary Gland Antibodies  >4 publications with CD80 and Mammary Gland
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