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TAF1C elisa kit :: Human TATA box binding protein (TBP) -associated factor, RNA polymerase I, C, 110kDa ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9338241 TAF1C elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TATA box binding protein (TBP) -associated factor, RNA polymerase I, C, 110kDa (TAF1C), ELISA Kit

★Popular Item★
 Also Known As   

Human TATA box-binding protein-associated factor RNA polymerase I subunit C, TAF1C ELISA Kit

 Product Synonym Names    Human TATA box-binding protein-associated factor RNA polymerase I subunit C (TAF1C) ELISA kit; MGC:39976; SL1; TAFI110; TAFI95; SL1; 110kD subunit; TBP-associated factor 1C; transcription factor SL1; TATA box binding protein (TBP) -associated factor; RNA polymerase I; C; 110kDa
 Product Gene Name   

TAF1C elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    604905
 3D Structure    ModBase 3D Structure for Q15572
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 Species Reactivity    Human
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TAF1C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TAF1C purchase    MBS9338241 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the TATA box binding protein (TBP) -associated factor, RNA polymerase I, C, 110kDa (TAF1C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing TAF1C, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9338241 kit is based on TAF1C antibody-TAF1C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TAF1C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TAF1C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for TAF1C elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TAF1C (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9338241. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TAF1C. It may not necessarily be applicable to this product.
 NCBI GI #    341926281
 NCBI GeneID    9013
 NCBI Accession #    NP_001230085.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001243156.1 [Other Products]
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 UniProt Primary Accession #    Q15572 [Other Products]
 UniProt Secondary Accession #    Q59F67; Q8N6V3; B7Z5K5; B7Z5S4; B7Z908; B7Z9L7 [Other Products]
 UniProt Related Accession #    Q15572 [Other Products]
 Molecular Weight    95,213 Da
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 NCBI Official Full Name    TATA box-binding protein-associated factor RNA polymerase I subunit C isoform 3
 NCBI Official Synonym Full Names    TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
 NCBI Official Symbol    TAF1C [Similar Products]
 NCBI Official Synonym Symbols   
SL1; TAFI95; TAFI110; MGC:39976
[Similar Products]
 NCBI Protein Information    TATA box-binding protein-associated factor RNA polymerase I subunit C; SL1, 110kD subunit; TBP-associated factor 1C; transcription factor SL1; TATA box-binding protein-associated factor 1C; transcription initiation factor SL1/TIF-IB subunit C; RNA polymerase I-specific TBP-associated factor 110 kDa; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD
 UniProt Protein Name    TATA box-binding protein-associated factor RNA polymerase I subunit C
 UniProt Synonym Protein Names   
RNA polymerase I-specific TBP-associated factor 110 kDa; TAFI110; TATA box-binding protein-associated factor 1C; TBP-associated factor 1C; Transcription initiation factor SL1/TIF-IB subunit C
 Protein Family    TATA box-binding protein-associated factor
 UniProt Gene Name    TAF1C [Similar Products]
 UniProt Synonym Gene Names    TAFI110; TBP-associated factor 1C [Similar Products]
 UniProt Entry Name    TAF1C_HUMAN
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 NCBI Summary for TAF1C    Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2011]
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 UniProt Comments for TAF1C    TAF1C: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: nucleoplasm

Molecular Function: protein binding; DNA binding

Biological Process: transcription from RNA polymerase II promoter; chromatin silencing at rDNA; negative regulation of gene expression, epigenetic; RNA elongation from RNA polymerase I promoter; transcription from RNA polymerase I promoter; gene expression; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; regulation of gene expression, epigenetic
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 Research Articles on TAF1C    1. Observational study of gene-disease association. (HuGE Navigator)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TAF1C elisa kitPathways associated with TAF1C elisa kit
 Reference Product  PubMed Publications
 TBP elisa kit  >9 publications with TAF1C and TBP
 TAF1B elisa kit  >5 publications with TAF1C and TAF1B
 TAF1A elisa kit  >5 publications with TAF1C and TAF1A
 MYC elisa kit  >1 publications with TAF1C and MYC
 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Polymerase I Chain Elongation Pathway antibodies  RNA Polymerase I Chain Elongation Pathway Diagram
 RNA Polymerase I Promoter Clearance Pathway antibodies  RNA Polymerase I Promoter Clearance Pathway Diagram
 RNA Polymerase I Promoter Escape Pathway antibodies  RNA Polymerase I Promoter Escape Pathway Diagram
 RNA Polymerase I Transcription Pathway antibodies  RNA Polymerase I Transcription Pathway Diagram
 RNA Polymerase I Transcription Initiation Pathway antibodies  RNA Polymerase I Transcription Initiation Pathway Diagram
 RNA Polymerase I Transcription Termination Pathway antibodies  RNA Polymerase I Transcription Termination Pathway Diagram
 RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway antibodies  RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway Diagram
Diseases associated with TAF1C elisa kitOrgans/Tissues associated with TAF1C elisa kit
 Disease Name  Pubmed Publications
 Mental Disorders Diagnosed in Childhood Antibodies  >1 publications with TAF1C and Mental Disorders Diagnosed in Childhood
 Neoplasms Antibodies  >1 publications with TAF1C and Neoplasms
 Cell Transformation, Neoplastic Antibodies  >1 publications with TAF1C and Cell Transformation, Neoplastic
 Autistic Disorder Antibodies  >1 publications with TAF1C and Autistic Disorder
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with TAF1C and Blood
 Thyroid Antibodies  >1 publications with TAF1C and Thyroid
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