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TIMP4 elisa kit :: Human TIMP metallopeptidase inhibitor 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703579 (SPECIAL PROMOTION: 20% OFF web price for 1x96-Strip-Wells Kit only.
Discount will be applied after order has been placed)
TIMP4 elisa kit
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,105 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,975 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TIMP metallopeptidase inhibitor 4 (TIMP4), ELISA Kit

 Also Known As   

Human tissue inhibitors of metalloproteinase 4, TIMP-4 ELISA Kit

 Product Synonym Names    Human tissue inhibitors of metalloproteinase 4; TIMP-4 ELISA Kit; tissue inhibitor of metalloproteinase 4; Human tissue inhibitors of metalloproteinase 4; TIMP-4
 Product Gene Name   

TIMP4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    601915
 3D Structure    ModBase 3D Structure for Q99727
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of human TIMP-4. No significant cross-reactivity or interference between human TIMP-4 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, human milk.
 Assay Type    Sandwich
 Detection Range    0.313 ng/ml -20 ng/ml.
 Sensitivity    0.005 ng/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of TIMP4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TIMP4 purchase    MBS703579 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the TIMP metallopeptidase inhibitor 4 (TIMP4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.313 ng/ml -20 ng/ml in biological research samples containing TIMP4, with an estimated sensitivity of 0.005 ng/ml. The ELISA analytical biochemical technique of the MBS703579 kit is based on TIMP4 antibody-TIMP4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TIMP4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TIMP4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, human milk. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for TIMP4 elisa kit

   Principle of the Assay||This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TIMP-4 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TIMP-4 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TIMP-4 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TIMP-4 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS703579
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NCBI/Uniprot data below describe general gene information for TIMP4. It may not necessarily be applicable to this product.
 NCBI GI #    4507515
 NCBI GeneID    7079
 NCBI Accession #    NP_003247.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003256.3 [Other Products]
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 UniProt Primary Accession #    Q99727 [Other Products]
 UniProt Secondary Accession #    B2R7K6 [Other Products]
 UniProt Related Accession #    Q99727 [Other Products]
 Molecular Weight    25,503 Da
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 NCBI Official Full Name    metalloproteinase inhibitor 4
 NCBI Official Synonym Full Names    TIMP metallopeptidase inhibitor 4
 NCBI Official Symbol    TIMP4 [Similar Products]
 NCBI Protein Information    metalloproteinase inhibitor 4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4
 UniProt Protein Name    Metalloproteinase inhibitor 4
 UniProt Synonym Protein Names   
Tissue inhibitor of metalloproteinases 4; TIMP-4
 Protein Family    Metalloproteinase inhibitor
 UniProt Gene Name    TIMP4 [Similar Products]
 UniProt Synonym Gene Names    TIMP-4 [Similar Products]
 UniProt Entry Name    TIMP4_HUMAN
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 NCBI Summary for TIMP4    This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TIMP4    Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7 and MMP-9.
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 Research Articles on TIMP4    1. Selective myocardial targeting for TIMP-4 induction through either a viral or transgenic approach favorably altered the course of adverse left ventricular remodeling post-myocardial infarction.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TIMP4 elisa kitPathways associated with TIMP4 elisa kit
 Reference Product  PubMed Publications
 MMP2 elisa kit  >21 publications with TIMP4 and MMP2
 MMP9 elisa kit  >18 publications with TIMP4 and MMP9
 MMP13 elisa kit  >11 publications with TIMP4 and MMP13
 MMP3 elisa kit  >10 publications with TIMP4 and MMP3
 MMP14 elisa kit  >6 publications with TIMP4 and MMP14
 MMP7 elisa kit  >5 publications with TIMP4 and MMP7
 MMP26 elisa kit  >1 publications with TIMP4 and MMP26
 Products by Pathway  Pathway Diagram
 Matrix Metalloproteinases Pathway antibodies  Matrix Metalloproteinases Pathway Diagram
Diseases associated with TIMP4 elisa kitOrgans/Tissues associated with TIMP4 elisa kit
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >19 publications with TIMP4 and Cardiovascular Diseases
 Inflammation Antibodies  >9 publications with TIMP4 and Inflammation
 Nervous System Diseases Antibodies  >7 publications with TIMP4 and Nervous System Diseases
 Disease Models, Animal Antibodies  >6 publications with TIMP4 and Disease Models, Animal
 Myocardial Infarction Antibodies  >6 publications with TIMP4 and Myocardial Infarction
 Necrosis Antibodies  >6 publications with TIMP4 and Necrosis
 Hypertrophy Antibodies  >5 publications with TIMP4 and Hypertrophy
 Immune System Diseases Antibodies  >4 publications with TIMP4 and Immune System Diseases
 Atherosclerosis Antibodies  >4 publications with TIMP4 and Atherosclerosis
 Lung Neoplasms Antibodies  >3 publications with TIMP4 and Lung Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >13 publications with TIMP4 and Bone
 Connective Tissue Antibodies  >4 publications with TIMP4 and Connective Tissue
 Heart Antibodies  >3 publications with TIMP4 and Heart
 Muscle Antibodies  >3 publications with TIMP4 and Muscle
 Brain Antibodies  >3 publications with TIMP4 and Brain
 Vascular Antibodies  >2 publications with TIMP4 and Vascular
 Embryonic Tissue Antibodies  >2 publications with TIMP4 and Embryonic Tissue
 Ear Antibodies  >1 publications with TIMP4 and Ear
 Kidney Antibodies  >1 publications with TIMP4 and Kidney
 Umbilical Cord Antibodies  >1 publications with TIMP4 and Umbilical Cord
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