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TLN1 elisa kit :: Human Talin-1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS763026
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $300 +1 FREE 8GB USB
96-Strip-Wells  /  $415 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,825 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,425 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Talin-1 (TLN1), ELISA Kit

★Popular Item★
 Also Known As   

Human Talin-1 ELISA Kit

 Product Synonym Names    TLN1 (Talin-1)/KIAA1027/ILWEQ/KIAA1027/talin 1/talin-1/TLN
 Product Gene Name   

TLN1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS763026 COA    COA PDF
 OMIM    186745
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 Species Reactivity    Human
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 Specificity    This assay has high sensitivity and excellent specificity for detection of TLN1. No significant cross-reactivity or interference between TLN1 and analogues was observed.
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 Samples    Serum, plasma and other biological fluids.
 Assay Type    Sandwich ELISA, Double Antibody
 Detection Range    0.156-10ng/ml
 Sensitivity    0.094ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level TLN1 were tested 20 times on one plate, respectively. Intra-Assay: CV<8%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level TLN1 were tested on 3 different plates, 8 replicates in each plate. CV (%) = SD/meanX100. Inter-Assay: CV<10%
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 Preparation and Storage    Store at 4 degree C if kit is to be used within 1 week. Stable for 6 months (if micro ELISA Plate, Lyophilized Standard and Concentrated Biotinylated Detection Protein stored at-20 degree C. Other components at 2-8 degree C). Stable for 12 months (if the entire kit is stored at-20 degree C).
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TLN1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TLN1 purchase    MBS763026 is a ready-to-use microwell, strip plate Sandwich, Double Antibody ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Talin-1 (TLN1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10ng/ml in biological research samples containing TLN1, with an estimated sensitivity of 0.094ng/ml. The ELISA analytical biochemical technique of the MBS763026 kit is based on TLN1 antibody-TLN1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TLN1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TLN1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for TLN1 elisa kit

   Principle of the Assay: This kit was based on sandwich enzyme-linked immune-sorbent assay technology. Anti- TLN1 antibody was pre-coated onto 96-well plates. And the biotin conjugated anti- TLN1 antibody was used as detection antibodies. The standards, test samples and biotin conjugated detection antibody were added to the wells subsequently, and wash with wash buffer. HRP-Streptavidin was added and unbound conjugates were washed away with wash buffer. TMB substrates were used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the TLN1 amount of sample captured in plate. Read the O.D. absorbance at 450nm in a microplate reader, and then the concentration of TLN1 can be calculated.
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 Typical Testing Data/Standard Curve (for reference only) of TLN1 elisa kit    TLN1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS763026. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TLN1. It may not necessarily be applicable to this product.
 NCBI GI #    223029410
 NCBI GeneID    7094
 NCBI Accession #    NP_006280.3 [Other Products]
 NCBI GenBank Nucleotide #    NM_006289.3 [Other Products]
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 UniProt Secondary Accession #    Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; A6NMY0 [Other Products]
 UniProt Related Accession #    Q9Y490 [Other Products]
 Molecular Weight    269,767 Da
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 NCBI Official Full Name    talin-1
 NCBI Official Synonym Full Names    talin 1
 NCBI Official Symbol    TLN1 [Similar Products]
 NCBI Official Synonym Symbols   
TLN; ILWEQ
[Similar Products]
 NCBI Protein Information    talin-1
 UniProt Protein Name    Talin-1
 Protein Family    Talin
 UniProt Gene Name    TLN1 [Similar Products]
 UniProt Synonym Gene Names    KIAA1027; TLN [Similar Products]
 UniProt Entry Name    TLN1_HUMAN
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 NCBI Summary for TLN1    This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
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 UniProt Comments for TLN1    Talin-1: a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 9p13

Cellular Component: cell surface; cytoplasm; cytosol; extracellular region; focal adhesion; intercellular junction; microtubule organizing center; plasma membrane; ruffle

Molecular Function: actin filament binding; integrin binding; LIM domain binding; protein binding; structural constituent of cytoskeleton; vinculin binding

Biological Process: axon guidance; blood coagulation; cell motility; cell-substrate junction assembly; cellular protein metabolic process; cortical actin cytoskeleton organization and biogenesis; cytoskeletal anchoring; intercellular junction assembly; muscle contraction; platelet activation; platelet degranulation; unfolded protein response; viral reproduction
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 Research Articles on TLN1    1. Our data demonstrate that high expression of Talin-1 is associated with significantly poorer OS and poorer DMFS in NPC and depletion of Talin-1 expression inhibited NPC cell migration and invasion. Talin-1 may serve as novel prognostic biomarker in NPC.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TLN1 elisa kitPathways associated with TLN1 elisa kit
 Reference Product  PubMed Publications
 PTK2 elisa kit  >3 publications with TLN1 and PTK2
 ITGB1 elisa kit  >3 publications with TLN1 and ITGB1
 CAPN2 elisa kit  >2 publications with TLN1 and CAPN2
 VCL elisa kit  >1 publications with TLN1 and VCL
 ITGB3 elisa kit  >1 publications with TLN1 and ITGB3
 Products by Pathway  Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Downstream Signal Transduction Pathway antibodies  Downstream Signal Transduction Pathway Diagram
 Downstream Signaling Of Activated FGFR1 Pathway antibodies  Downstream Signaling Of Activated FGFR1 Pathway Diagram
 Downstream Signaling Of Activated FGFR2 Pathway antibodies  Downstream Signaling Of Activated FGFR2 Pathway Diagram
 Downstream Signaling Of Activated FGFR3 Pathway antibodies  Downstream Signaling Of Activated FGFR3 Pathway Diagram
Diseases associated with TLN1 elisa kitOrgans/Tissues associated with TLN1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasm Invasiveness Antibodies  >6 publications with TLN1 and Neoplasm Invasiveness
 Cardiovascular Diseases Antibodies  >5 publications with TLN1 and Cardiovascular Diseases
 Liver Diseases Antibodies  >4 publications with TLN1 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >4 publications with TLN1 and Carcinoma, Hepatocellular
 Breast Neoplasms Antibodies  >4 publications with TLN1 and Breast Neoplasms
 Genital Diseases, Male Antibodies  >3 publications with TLN1 and Genital Diseases, Male
 Cell Transformation, Neoplastic Antibodies  >3 publications with TLN1 and Cell Transformation, Neoplastic
 Death Antibodies  >3 publications with TLN1 and Death
 Nervous System Diseases Antibodies  >2 publications with TLN1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >2 publications with TLN1 and Disease Models, Animal
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with TLN1 and Blood
 Bone Antibodies  >6 publications with TLN1 and Bone
 Vascular Antibodies  >5 publications with TLN1 and Vascular
 Liver Antibodies  >4 publications with TLN1 and Liver
 Brain Antibodies  >4 publications with TLN1 and Brain
 Prostate Antibodies  >4 publications with TLN1 and Prostate
 Lymph Antibodies  >3 publications with TLN1 and Lymph
 Lymph Node Antibodies  >3 publications with TLN1 and Lymph Node
 Heart Antibodies  >3 publications with TLN1 and Heart
 Muscle Antibodies  >3 publications with TLN1 and Muscle
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