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TNX elisa kit :: Human Tenascin X ELISA Kit

Scan QR to view Datasheet Catalog #    MBS728659
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells-(Competitive)  /  $455 +1 FREE 8GB USB
48-Strip-Wells-(Sandwich)  /  $455 +1 FREE 8GB USB
96-Strip-Wells-(Competitive)  /  $660 +1 FREE 8GB USB
96-Strip-Wells-(Sandwich)  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells-(Competitive)  /  $2,925 +3 FREE 8GB USB
5x96-Strip-Wells-(Sandwich)  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells-(Competitive)  /  $5,490 +6 FREE 8GB USB
10x96-Strip-Wells-(Sandwich)  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tenascin X (TNX), ELISA Kit

 Also Known As   

Human Tenascin X ELISA Kit

 Product Gene Name   

TNX elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    gene 606408
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 Species Reactivity    Human
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive or Sandwich
 Detection Range    5.0-100ng/mL
 Sensitivity    1.0ng/mL
 Highest Standards    100ng/mL
 Concentration of Standards    Concentration of Standards
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TNX elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TNX purchase    MBS728659 is a ready-to-use microwell, strip plate Competitive or Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tenascin X (TNX) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 5.0-100ng/mL in biological research samples containing TNX, with an estimated sensitivity of 1.0ng/mL. The ELISA analytical biochemical technique of the MBS728659 kit is based on TNX antibody-TNX antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNX antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNX. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for TNX elisa kit    Neurobiology
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 Typical Testing Data/Standard Curve (for reference only) of TNX elisa kit    TNX elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS728659. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TNX. It may not necessarily be applicable to this product.
 NCBI GI #    20665034
 NCBI GeneID    7148
 NCBI Accession #    NP_115859.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_032470.3 [Other Products]
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 UniProt Secondary Accession #    P78530; P78531; Q08424; Q08AM0; Q08AM1; Q59GU7; Q5SQD3; Q5ST74; Q7L8Q4; Q8N4R1; Q9NPK9 [Other Products]
 UniProt Related Accession #    P22105 [Other Products]
 Molecular Weight    458,220 Da
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 NCBI Official Full Name    tenascin-X isoform 2
 NCBI Official Synonym Full Names    tenascin XB
 NCBI Official Symbol    TNXB [Similar Products]
 NCBI Official Synonym Symbols   
XB; TNX; XBS; EDS3; HXBL; TENX; TN-X; VUR8; TNXB1; TNXB2; TNXBS
[Similar Products]
 NCBI Protein Information    tenascin-X; tenascin XB1; tenascin XB2; hexabrachion-like protein; growth-inhibiting protein 45
 UniProt Protein Name    Tenascin-X
 UniProt Synonym Protein Names   
Hexabrachion-like protein
 UniProt Gene Name    TNXB [Similar Products]
 UniProt Synonym Gene Names    HXBL; TNX; TNXB1; TNXB2; XB; TN-X [Similar Products]
 UniProt Entry Name    TENX_HUMAN
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 NCBI Summary for TNX    This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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 UniProt Comments for TNX    TNXB: Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors. Defects in TNXB are the cause of tenascin-X deficiency (TNXD). TNXD leads to an Ehlers-Danlos-like syndrome characterized by hyperextensible skin, hypermobile joints, and tissue fragility. Tenascin-X-deficient patients, however, lack atrophic scars, a major diagnostic criteria for classic Ehlers- Danlos. Delayed wound healing, which is also common in classic EDS, is only present in a subset of patients. Belongs to the tenascin family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide; Extracellular matrix

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: extracellular matrix; proteinaceous extracellular matrix; extracellular space; fibrillar collagen; intracellular

Molecular Function: integrin binding; collagen binding; heparin binding

Biological Process: elastic fiber assembly; cell-cell adhesion; triacylglycerol metabolic process; collagen fibril organization; collagen metabolic process; cell-matrix adhesion; regulation of JNK activity; fibril organization and biogenesis; actin cytoskeleton organization and biogenesis; fatty acid metabolic process; cell adhesion

Disease: Ehlers-danlos-like Syndrome Due To Tenascin-x Deficiency; Vesicoureteral Reflux 8
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 Research Articles on TNX    1. these results suggest that mutations in TNXB can cause hereditary primary vesicoureteral reflux .
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with TNX elisa kitDiseases associated with TNX elisa kit
 Products by Pathway  Pathway Diagram
 ECM Proteoglycans Pathway antibodies  ECM Proteoglycans Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 MicroRNAs In Cancer Pathway antibodies  MicroRNAs In Cancer Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >21 publications with TNX and Congenital Abnormalities
 Gonadal Disorders Antibodies  >12 publications with TNX and Gonadal Disorders
 Carcinoma Antibodies  >4 publications with TNX and Carcinoma
 Abnormalities, Multiple Antibodies  >4 publications with TNX and Abnormalities, Multiple
 Immune System Diseases Antibodies  >4 publications with TNX and Immune System Diseases
 Heart Defects, Congenital Antibodies  >2 publications with TNX and Heart Defects, Congenital
 Cardiovascular Abnormalities Antibodies  >1 publications with TNX and Cardiovascular Abnormalities
 Lung Neoplasms Antibodies  >1 publications with TNX and Lung Neoplasms
 Weight Loss Antibodies  >1 publications with TNX and Weight Loss
 Placenta Diseases Antibodies  >1 publications with TNX and Placenta Diseases
Organs/Tissues associated with TNX elisa kit
 Organ/Tissue Name  Pubmed Publications
 Connective Tissue Antibodies  >10 publications with TNX and Connective Tissue
 Skin Antibodies  >10 publications with TNX and Skin
 Blood Antibodies  >5 publications with TNX and Blood
 Muscle Antibodies  >4 publications with TNX and Muscle
 Kidney Antibodies  >3 publications with TNX and Kidney
 Heart Antibodies  >3 publications with TNX and Heart
 Nerve Antibodies  >2 publications with TNX and Nerve
 Eye Antibodies  >1 publications with TNX and Eye
 Placenta Antibodies  >1 publications with TNX and Placenta
 Lymph Antibodies  >1 publications with TNX and Lymph
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