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THBS1 elisa kit :: Human Thrombospondin-1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9502080
Testing Data
Unit / Price
96-Strip-Wells  /  $440 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Thrombospondin-1 (THBS1), ELISA Kit

★Popular Item★
 Also Known As   

Thrombospondin-1 (Human) OmniKine ELISA Kit

 Product Synonym Names    TSP; TSP1
 Product Gene Name   

THBS1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    X04665 mRNA
 3D Structure    ModBase 3D Structure for P07996
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 Species Reactivity    Human
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 Specificity    The OmniKine Human Thrombospondin-1 ELISA is capable of recognizing both recombinant and naturally produced Human Thrombospondin-1 proteins. The antigens listed below were tested at 1000 ng/ml and did not exhibit significant cross reactivity or interference.
Human: CD36, Latent TGF-beta1, Thrombospondin-2, Thrombospondin-4
 Form/Format    12 x 8-Well Microstrips
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 Samples    Plasma, serum, lysate
 Assay Type    Sandwich ELISA
 Detection Range    1563-100000 pg/ml
 Sensitivity    1563-100000 pg/ml
 Detection Method    Colorimetric 450 nm
 Subtype    None
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 Preparation and Storage    Store at 4 degree C for 6 months.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of THBS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for THBS1 purchase    MBS9502080 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Thrombospondin-1 (THBS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1563-100000 pg/ml in biological research samples containing THBS1, with an estimated sensitivity of 1563-100000 pg/ml. The ELISA analytical biochemical technique of the MBS9502080 kit is based on THBS1 antibody-THBS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect THBS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, THBS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Plasma, serum, lysate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Testing Data of THBS1 elisa kit    The OmniKine Human Thrombospondin-1 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Thrombospondin-1 proteins within the range of 1563-100000 pg/ml.
THBS1 elisa kit Testing Data image
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Sample Manual Insert of MBS9502080. Click to request current manual
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NCBI/Uniprot data below describe general gene information for THBS1. It may not necessarily be applicable to this product.
 NCBI GI #    40317626
 NCBI GeneID    7057
 NCBI Accession #    NP_003237.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_003246.3 [Other Products]
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 UniProt Primary Accession #    P07996 [Other Products]
 UniProt Secondary Accession #    Q15667; Q59E99; A8K6H4; B4E3J7; B9EGH6 [Other Products]
 UniProt Related Accession #    P07996 [Other Products]
 Molecular Weight    120,148 Da
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 NCBI Official Full Name    thrombospondin-1
 NCBI Official Synonym Full Names    thrombospondin 1
 NCBI Official Symbol    THBS1 [Similar Products]
 NCBI Official Synonym Symbols   
TSP; THBS; TSP1; TSP-1; THBS-1
[Similar Products]
 NCBI Protein Information    thrombospondin-1
 UniProt Protein Name    Thrombospondin-1
 Protein Family    Thrombospondin
 UniProt Gene Name    THBS1 [Similar Products]
 UniProt Synonym Gene Names    TSP; TSP1 [Similar Products]
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 NCBI Summary for THBS1    The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. [provided by RefSeq, Jul 2008]
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 UniProt Comments for THBS1    THBS1: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Binds heparin. May play a role in dentinogenesis and/or maintenance of dentin and dental pulp. Ligand for CD36 mediating antiangiogenic properties. Belongs to the thrombospondin family.

Protein type: Inhibitor; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; external side of plasma membrane; extracellular matrix; extracellular region; extracellular space; fibrinogen complex; sarcoplasmic reticulum; secretory granule

Molecular Function: calcium ion binding; fibroblast growth factor binding; fibronectin binding; heparin binding; identical protein binding; integrin binding; laminin binding; low-density lipoprotein particle binding; phosphatidylserine binding; protein binding; proteoglycan binding; transforming growth factor beta binding

Biological Process: activation of MAPK activity; behavioral response to pain; cell adhesion; cell cycle arrest; cell migration; chronic inflammatory response; engulfment of apoptotic cell; extracellular matrix organization; immune response; inflammatory response; negative regulation of angiogenesis; negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; negative regulation of apoptosis; negative regulation of blood vessel endothelial cell migration; negative regulation of cell-matrix adhesion; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; negative regulation of dendritic cell antigen processing and presentation; negative regulation of endothelial cell proliferation; negative regulation of fibrinolysis; negative regulation of fibroblast growth factor receptor signaling pathway; negative regulation of focal adhesion assembly; negative regulation of interleukin-12 production; peptide cross-linking; platelet degranulation; positive regulation of angiogenesis; positive regulation of blood coagulation; positive regulation of blood vessel endothelial cell migration; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of chemotaxis; positive regulation of macrophage activation; positive regulation of phosphorylation; positive regulation of protein kinase B signaling; positive regulation of smooth muscle cell proliferation; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of transforming growth factor beta1 production; positive regulation of translation; positive regulation of tumor necrosis factor biosynthetic process; regulation of cGMP metabolic process; regulation of megakaryocyte differentiation; response to calcium ion; response to drug; response to glucose stimulus; response to hypoxia; response to magnesium ion; response to mechanical stimulus; response to progesterone; response to testosterone stimulus; response to unfolded protein; sprouting angiogenesis
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 Research Articles on THBS1    1. These findings shed light on the mechanisms leading to beta-cell failure during metabolic stress and point to THBS1 as an interesting therapeutic target to prevent oxidative stress in type 2 diabetes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with THBS1 elisa kit
 Products by Pathway  Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 ECM-receptor Interaction Pathway antibodies  ECM-receptor Interaction Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Inflammatory Response Pathway antibodies  Inflammatory Response Pathway Diagram
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