NP_001298089.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,935 Da
NCBI Official Full Name
thy-1 membrane glycoprotein preproprotein
NCBI Official Synonym Full Names
Thy-1 cell surface antigen
NCBI Official Synonym Symbols
NCBI Protein Information
thy-1 membrane glycoprotein
UniProt Protein Name
Thy-1 membrane glycoprotein
UniProt Synonym Protein Names
CDw90; Thy-1 antigen; CD_antigen: CD90
UniProt Entry Name
THY1_HUMAN
NCBI Summary for THY1
This gene encodes a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. The encoded protein is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. The encoded protein is widely used as a marker for hematopoietic stem cells. This gene may function as a tumor suppressor in nasopharyngeal carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
UniProt Comments for THY1
THY1: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Protein type: Motility/polarity/chemotaxis; Cell adhesion; Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 11q23.3
Cellular Component: anchored to external side of plasma membrane; apical plasma membrane; cytosol; dendrite; endoplasmic reticulum; external side of plasma membrane; focal adhesion; growth cone; integral to plasma membrane; lipid raft; myelin sheath; plasma membrane
Molecular Function: GTPase activator activity; integrin binding; protein binding; protein kinase binding
Biological Process: angiogenesis; cell-cell adhesion; cytoskeleton organization and biogenesis; focal adhesion formation; negative regulation of axonogenesis; negative regulation of cell migration; negative regulation of protein kinase activity; negative regulation of T cell receptor signaling pathway; positive regulation of GTPase activity; positive regulation of release of sequestered calcium ion into cytosol; positive regulation of T cell activation; protein amino acid autophosphorylation; retinal cone cell development; T cell receptor signaling pathway
Research Articles on THY1
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Products associated with THY1 elisa kit
Pathways associated with THY1 elisa kit
Diseases associated with THY1 elisa kit
Organs/Tissues associated with THY1 elisa kit
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